Browsing Science (Faculty of) by Title
Now showing items 1534-1553 of 3018
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Investigations into food web structure in the Beaufort Sea
(University of Waterloo, 2017-12-18)The effects of climate change on marine ecosystems are most pronounced in the Arctic, where ice free summers have been predicted to occur by mid-century. Climate-related changes to sea ice phenology, oceanographic habitat ... -
Investigations into Intracellular Thiols of Biological Importance
(University of Waterloo, 2007-02-01)The presence of thiols in living systems is critical for the maintenance of cellular redox homeostasis, the maintenance of protein thiol-disulfide ratios and the protection of cells from reactive oxygen species. In addition ... -
Investigations into Streptomyces azureus Thiostrepton-resistance rRNA Methyltransferase and its Cognate Antibiotic
(University of Waterloo, 2008-12-16)Thiostrepton (TS: TS; C72H85N19O18S5) is a thiazoline antibiotic that is effective against Gram-positive bacteria and the malarial parasite, Plasmodium falciparum. Tight binding of TS to the bacterial L11-23S ribosomal RNA ... -
Investigations into the toxicity and toxicokinetics of individual and binary mixtures of CCME petroleum hydrocarbon distillates in soil
(University of Waterloo, 2012-05-18)The Canada-wide Standards for Petroleum Hydrocarbons (PHC CWS) in soils are remedial standards based on four petroleum distillates (Fraction 1 [F1; ECN C6-C10], Fraction 2 [F2; ECN >C10-C16], Fraction 3 [F3; ECN >C16-C34], ... -
Investigations of Bacterial Methionine Aminopeptidase
(University of Waterloo, 2009-10-05)The pathway representing methionine integration and excision is an increasingly important target in drug design. Methionine aminopeptidase (MetAP), a metalloprotease responsible for cleaving the N-terminal methionine from ... -
Investigations of InAsP/InP Semiconductor Devices for Quantum Communication Technologies
(University of Waterloo, 2015-01-19)This thesis presents a set of magnetotransport experiments which explore the advantages of InAsP/InP quantum well material and quantum dot structures for spin/photon devices, with a view towards quantum communication. The ... -
Investigations of Magnetic Model Systems Using Coupled Cluster Based Approaches
(University of Waterloo, 2017-08-23)Over the past decades, the quantum mechanical description of magnetic phenomena has been well developed. However, the first principle calculations of the physical properties of magnetic systems is still a challenge. One ... -
Investigations of the Natural Product Antibiotic Thiostrepton from Streptomyces azureus and Associated Mechanisms of Resistance
(University of Waterloo, 2013-03-11)The persistence and propagation of bacterial antibiotic resistance presents significant challenges to the treatment of drug resistant bacteria with current antimicrobial chemotherapies, while a dearth in replacements for ... -
Investigations on the action mode of Bacillus thuringiensis Cyt2Aa1 toxin
(University of Waterloo, 2015-08-11)B. thuringiensis is a Gram-positive bacterium that, while quite otherwise closely related to the soil saprophyte Bacillus cereus, is unique in producing a large variety of membrane-damaging, insecticidal protein toxins. ... -
Investigations on the Oligomerization of Pyolysin, a Cholesterol-Dependent Cytolysin
(University of Waterloo, 2011-01-25)The bacterial toxin pyolysin (PLO) is a member of the family of Cholesterol-Dependent Cytolysins, which form large, oligomeric pores in cholesterol-containing membranes. The general CDC structure has an elongated shape and ... -
Investigations on the Reptilian Spectacle
(University of Waterloo, 2012-12-12)The eyes of snakes and most geckos, as well as a number of other disparate squamate taxa, are shielded beneath a layer of transparent integument referred to as the “reptilian spectacle.” Derived from the embryonic fusion ... -
Iron isotope fractionation in sediments of an oligotrophic freshwater lake
(University of Waterloo, 2015-10-06)In situ iron (Fe) isotope compositions of pore water and solid-bound Fe phases were measured in sediments of an oligotrophic, sulfate-poor freshwater lake (Lake Tantaré, Québec, Canada). Previous work has shown that ... -
Iron Isotope Fractionations Reveal a Finite Bioavailable Fe Pool for Structural Fe(III) Reduction in Nontronite
(American Chemical Society, 2017-08-16)We report on stable Fe isotope fractionation during microbial and chemical reduction of structural Fe(III) in nontronite NAu-1. Fe-56/Fe-54 fractionation factors between aqueous Fe(II) and structural Fe(III) ranged from ... -
Iron oxide nanozyme catalyzed synthesis of fluorescent polydopamine for light-up Zn2+ detection
(Royal Society of Chemistry, 2016-07-29)Fluorescent polydopamine (FPD) is an interesting material with excellent biocompatibility. However, its preparation is currently a lengthy and potentially dangerous process. We herein employ magnetic iron oxide (Fe3O4) ... -
Is blur sensitivity altered in children with progressive myopia?
(Elsevier, 2019-01)School aged children with progressive myopia show large accommodative lags to blur only cue which is suggestive of a large depth of focus (DOF). While DOF measures are lacking in this age group, their blur detection and ... -
Island biogeography theory and the urban landscape: stopover site selection by the silver-haired bat (Lasionycteris noctivagans)
(Canadian Science Publishing, 2022-04)Many migratory bats require forested sites for roosting and foraging along their migration path, but increased urbanization and intensive agricultural practices may reduce the availability of stopover sites. Urban forests ... -
Isolation and characterization of bacterial phosphorous metabolism genes from complex microbial communities
(University of Waterloo, 2009-10-05)Phosphorous (P) is an essential nutrient, playing a central role in the life of a bacterial cell. It is involved in cellular metabolic pathways, cell signaling and is a component of many of the cell’s macromolecules. Since ... -
Isolation and Characterization of Host Mutations that Suppress the Bacteriophage Lambda (λ) Rex Phenotype
(University of Waterloo, 2015-09-01)The Bacteriophage lambda (λ) T4rII exclusion (Rex) phenotype is defined as the inability of T4rII mutant bacteriophage to form plaques on a lawn of E. coli lysogenized by bacteriophage λ. More than six decades have passed ... -
Isotope hydrology and paleohydrology of the Slave River Delta, NWT
(University of Waterloo, 2010-08-30)Water isotope tracers and multi-proxy paleolimnological approaches are used to characterize the present and past hydrology of the Slave River Delta (SRD), NWT. This research addresses crucial gaps in knowledge about the ... -
Isotope-Inferred Water Balance of Slave River Delta Lakes, NWT, Canada.
(University of Waterloo, 2007-09-27)The use of the stable isotopes, 18O and 2H, has proven to be a valuable tool in determining the importance of various hydrological controls on the modern water balances of Slave River Delta lakes, NWT, Canada. Samples ...