Browsing Science (Faculty of) by Title
Now showing items 1897-1916 of 2849
-
Pain Management within the Long-term Care Setting: An Inquiry into Staff-perceived Contemporary Pain Management Practices
(University of Waterloo, 2014-05-06)Background: Chronic pain is a frequent and undertreated ailment within the long-term care community (Herman et al, 2009). The likelihood of experiencing pain increases with age and failure to treat this condition may ... -
Paleo-Ice Sheet and Deglacial History of the Southwestern Great Slave Lake Area
(University of Waterloo, 2022-01-28)The western Laurentide Ice Sheet (LIS) is known to have experienced complex ice-flow shifts during the last glaciation due to ice divide migration and increasing topographic influence during deglaciation. Several glacial ... -
Paleoglaciological dynamics in northern Manitoba and the subglacial bed mosaic
(University of Waterloo, 2013-06-24)During the last glacial maximum (LGM), some 20 ka ago, northern Manitoba was situated beneath 3 to 4.5 km of ice, on the outer fringe of a major ice spreading center of the Laurentide Ice Sheet. The region has also been ... -
Paleohydrology of the Wabasca River and relations with past flood regimes at the downstream Peace-Athabasca Delta
(University of Waterloo, 2022-08-22)The Peace-Athabasca Delta (PAD; northern Alberta) is internationally recognized for its ecological, historical, and cultural significance, yet controversy persists over the roles of hydroelectric regulation of Peace River ... -
Paleolimnological evidence of the effects of recent cultural eutrophication and climatic variability during the last 300 years in Lake Malawi, East Africa
(University of Waterloo, 2005)Lake Malawi is the second largest lake in Africa, supporting diverse populations of endemic cichlids and supplying essential water resources to Malawi, Mozambique and Tanzania. However, population growth, rapid deforestation ... -
Paleozoic evolution of western Marie Byrd Land, Antarctica
(Geological Society of America, 2015-09-01)We report geochemical data from (meta-) sedimentary and igneous rocks that crop out in the Ford Ranges of western Marie Byrd Land and discuss the evolution and reworking of the crust in this region during Paleozoic subduction ... -
Paleozoic transpressional tectonics in the Beishan orogenic collage, Northwest China: Evolution of the Hongliuhe suture zone
(University of Waterloo, 2016-01-21)The Beishan orogenic collage is a southern, central subset of the Central Asian Orogenic Belt, in Northwest China. It is an accretionary orogen that was active during the early Paleozoic, transitioning to convergent ... -
Paradigm Shift: Does River Metabolism Mask the Isotopic Signal of Nitrate Sources?
(University of Waterloo, 2017-05-19)Nitrate (NO₃⁻) is the most ubiquitous contaminant in surface and groundwaters in Canada. Synthetic fertilizer application and manure production in intensive agricultural areas contribute large quantities of NO₃⁻ to the ... -
Parallel Polyadenine Duplex Formation at Low pH Facilitates DNA Conjugation onto Gold Nanoparticles
(American Chemical Society, 2016-11-15)DNA-functionalized gold nanoparticles (AuNPs) have been extensively used in sensing, drug delivery, and materials science. A key step is to attach DNA to AuNPs, forming a stable and functional conjugate. Although the ... -
Parallel Polyadenine Duplex Formation at Low pH Facilitates DNA Conjugation onto Gold Nanoparticles
(University of Waterloo, 2017-04-20)DNA-functionalized gold nanoparticles (AuNPs) have been extensively used in sensing, drug delivery, and materials science. A key step is to attach DNA onto AuNPs forming a stable and functional conjugate. While the traditional ... -
A parallelized molecular collision cross section package with optimized accuracy and efficiency
(Royal Society of Chemistry, 2019)Ion mobility-based separation prior to mass spectrometry has become an invaluable tool in the structural elucidation of gas-phase ions and in the characterization of complex mixtures. Application of ion mobility to structural ... -
Parallelizing quantum circuit synthesis
(University of Waterloo, 2015-04-24)We present an algorithmic framework for parallel quantum circuit synthesis using meet-in-the-middle synthesis techniques. We also present two implementations thereof, using both threaded and hybrid parallelization ... -
Parameterization of In Silico Oral Disposition Models: Focus on Pediatrics
(University of Waterloo, 2017-03-16)Owing to their biologically relevant design, physiologically-based pharmacokinetic (PBPK) models require quantitative knowledge of organism anatomy and physiology to facilitate appropriate parameterization. Within such ... -
Part 1: Towards the Synthesis of Pyrene Zigzag Cyclacenes, Part 2: New Methods for the Synthesis of Conjugated Polymers
(University of Waterloo, 2021-09-30)Part 1: Carbon nanotubes (CNTs) are allotropes of carbon that have emerged as candidates for implementation in electronic devices ranging from transistors to solar cells. Unfortunately, the behavior of CNTs is highly ... -
Partial oligomerization of pyolysin induced by a disulfide-tethered mutant
(NRC Research Press, 2012-12)The bacterial toxin pyolysin (PLO) belongs to the family of cholesterol-dependent cytolysins (CDCs), which form large, ring-shaped oligomeric pores in cholesterol-containing membranes. Monomeric CDC molecules have a structure ... -
Particle Distributions in a Block Copolymer Nanocomposite
(American Chemical Society, 2008)Self-consistent-field theory is used to predict the center-of-mass distribution of spherical nanoparticles embedded in the lamellar phase of a diblock copolymer melt. The calculation is performed in the dilute limit, where ... -
Parts-per-Million of Polyethylene Glycol as a Non-Interfering Blocking Agent for Homogeneous Biosensor Development
(American Chemical Society, 2013-11-05)Many homogeneous assays are complicated by the adsorption of probe molecules by the surface of reaction vessels, which are often made of polypropylene or polystyrene-based plastics. To solve this problem, many protein and ... -
Passive In Situ Treatment of Acidic and Neutral Mine Drainage: Field and Laboratory Investigations
(University of Waterloo, 2009-12-16)Water quality degradation is the foremost environmental issue faced by the mining industry. Negative impacts on water quality are commonly associated with unmitigated drainage emanating from sulfide-bearing mine waste ... -
Path Integral Approaches and Graphics Processing Unit Tools for Quantum Molecular Dynamics Simulations
(University of Waterloo, 2012-08-21)This thesis details both the technical and theoretical aspects of performing path integrals through classical Molecular Dynamics (MD) simulations. In particular, Graphics Processing Unit (GPU) computing is used to augment ... -
Path integral ground state approaches for the study of weakly bound clusters and confined molecules
(University of Waterloo, 2018-09-21)This thesis presents the study of weakly bound clusters in the ground state (or the zero-temperature limit) using path integral molecular dynamics. Specifically, we look individually at the quantum properties of small ...