Browsing Science (Faculty of) by Title
Now showing items 525-544 of 2850
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Daptomycin forms cation- and size-selective pores in model membranes
(Elsevier, 2014-10)Daptomycin is a lipopeptide antibiotic that is used clinically to treat severe infections caused by Gram-positive bacteria. Its bactericidal action involves the calcium-dependent binding to membranes containing ... -
Daptomycin: Mechanism of Action and Bacterial Resistance
(University of Waterloo, 2015-02-25)Daptomycin is an important lipopeptide antibiotic used for treating severe infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus ... -
Daptomycin: studies on its action mode and on bacterial resistance with model membranes
(University of Waterloo, 2016-05-16)Bacterial resistance to antibiotics is one of the most serious problems facing medicine today. Recently, reports have appeared describing bacteria that are resistant to daptomycin (dap), an important antibiotic used against ... -
Dark Matter and Neutrinos in the Foggy Universe
(University of Waterloo, 2019-01-07)Dark matter is predicted to be the main contribution to the matter content in the universe, in addition to ordinary baryonic matter such as protons and neutrons. However, we are limited in our knowledge of the nature of ... -
Data Analysis Protocol for the Development and Evaluation of Population Pharmacokinetic Models for Incorporation Into the Web-Accessible Population Pharmacokinetic Service - Hemophilia (WAPPS-Hemo)
(JMIR Publications, 2016-12-07)Background: Hemophilia is an inherited bleeding disorder caused by a deficiency in a specific clotting factor. This results in spontaneous bleeding episodes and eventual arthropathy. The mainstay of hemophilia treatment ... -
A Data Mining Approach for Detecting Evolutionary Divergence in Transcriptomic Data
(University of Waterloo, 2019-11-19)It has become common to produce genome sequences for organisms of scientific or popular interest. Although these genome projects provide insight into the gene and protein complements of a species including their evolutionary ... -
Data on removal kinetics of pharmaceutical compounds, artificial sweeteners, and perfluoroalkyl substances from water using a passive treatment system containing zero-valent iron and biochar
(Elsevier, 2019-12)The data presented in this paper relate to the research paper “Removal of pharmaceutical compounds, artificial sweeteners, and perfluoroalkyl substances from water using a passive treatment system containing zero-valent ... -
The data processing pipeline for the Herschel1 - HIFI instrument
(Elsevier, 2019-04)The HIFI data processing pipeline was developed to systematically process diagnostic, calibration and astronomical observations taken with the HIFI science instrument as part of the Herschel mission. The HIFI pipeline ... -
Data-driven and Hamiltonian-driven Quantum Simulations with Generative Models
(University of Waterloo, 2022-01-12)In the era of noisy intermediate-scale quantum devices (NISQ), a paradigm shift is occurring in the numerical physics community to transition towards developing algorithms that facilitate experimental realizations of quantum ... -
Deciphering the Indoleacetic Acid Biosynthesis Pathways in the Rhizobacterium Pseudomonas sp. UW4
(University of Waterloo, 2017-09-25)Healthy plants host, within and on the surfaces of their tissues, diverse endophytic and epiphytic bacteria. Often, this interaction is mutualistic, leading to adaptive benefits for both partners. We refer to these ... -
Deciphering the Toxicity Effects of 5′-Methylthioadenosine Accumulation in Arabidopsis thaliana
(University of Waterloo, 2021-09-29)Metabolic constraints imposed by extreme environmental fluctuations are an inescapable reality for sessile organisms such as plants. To survive, they finely tune their metabolic activity to adapt their growth to the ... -
Decoherence by a non-Markovian and non-Gaussian Environment
(University of Waterloo, 2013-01-25)This thesis studies a spin-star model and an open spin-star model. The spin-star model is exactly solvable, and the approximation methods can be applied and compared with the exact solution. As this model is shown to be ... -
Decoupling of a neutron interferometer from temperature gradients
(AIP Publishing, 2016-12-16)Neutron interferometry enables precision measurements that are typically operated within elaborate, multi-layered facilities which provide substantial shielding from environmental noise. These facilities are necessary to ... -
Decoy-State Quantum Key Distribution with Arbitrary Phase Mixtures and Phase Correlations
(University of Waterloo, 2022-01-26)We formulate a general method to find bounds on the statistics of states passing through an unknown channel from the statistics of another set of states. We pay special attention to the application of this method to ... -
Deep Generative Modeling Based Retinal Image Analysis
(University of Waterloo, 2020-06-16)In the recent past, deep learning algorithms have been widely used in retinal image analysis (fundus and OCT) to perform tasks like segmentation and classification. But to build robust and highly efficient deep learning ... -
Defect-Rich Size-Selected Nanoclusters and Nanocrystalline Films of Titanium (IV) Oxide and Tantalum (IV) Oxide for Efficient Photocatalyst and Electroforming-Free Memristor Applications
(University of Waterloo, 2016-05-16)Transition metal oxides, TiO2 and Ta2O5, are two of the most extensively studied wide bandgap semiconductor materials (with high work functions). Due to their suitable band edge positions for hydrogen evolution and exceptional ... -
Defect-rich Titanium (IV) Oxide and Zirconium (IV) Oxide Nanostructures for Ultra-efficient Photocatalyst and High-Tc Dilute Ferromagnetic Semiconductor Applications
(University of Waterloo, 2016-05-16)In transparent conductive oxide nanostructures, oxygen vacancy defects (neutral, singly charged, and doubly charged defects) are found to be one of the most important and prevalent defects due to the enhancement of light ... -
Defects and Boundaries in Quantum Field Theories
(University of Waterloo, 2021-07-29)We discuss some aspects of defects and boundaries in quantum field theories (QFTs) and their applications in revealing non-perturbative aspects of QFTs in combination with other techniques, including integrability. ... -
Deformation History of the Black Bay Fault, Northwest Territories, Canada
(University of Waterloo, 2018-09-10)The Black Bay Fault is a major Paleoproterozoic, NE-SW-trending, crustal-scale feature that separates different tectonometamorphic domains of the southern Rae craton in the Canadian Shield. This structure extends from the ... -
Degradable starch nanoparticle assisted ethanol precipitation of DNA
(Elsevier, 2014-04-18)Precipitation of DNA from a large volume of aqueous solution is an important step in many molecular biology and analytical chemistry experiments. Currently, this is mainly achieved by ethanol precipitation, where a long-term ...