Science (Faculty of)
Welcome to the Faculty of Science community.
This community and its collections are organized using the University of Waterloo's Faculties and Academics structure. In this structure:
- Communities are Faculties or Affiliated Institutions
- Collections are Departments or Research Centres
Research outputs are organized by type (eg. Master Thesis, Article, Conference Paper).
New collections following this structure will be created UPON REQUEST .
Collections in this community
Recent deposits
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Exploring the Structures and Properties of Cationic Aromatic Clusters
(University of Waterloo, 2020-12-02)In this thesis, the structures and properties of protonated aromatic clusters have been investigated. The aromaticity of the phenyl ring can be influenced by the substituents. Electron withdrawing groups (EWGs) can reduce ... -
Growth of rainbow darter (Etheostoma caeruleum) in the Grand River watershed
(University of Waterloo, 2020-11-27)Assessment of growth is an important tool in fisheries assessment and management and provides valuable insight into biological responses to stressors in biomonitoring programs. A small-bodied fish species, rainbow darter ... -
Arborescent Core–Shell–Corona Copolymers by Self-Assembly as Templates for the Preparation of Metallic Nanoparticles
(University of Waterloo, 2020-11-19)The preparation of metallic nanoparticles has been a rapidly growing field of research in recent years, because of the unique physical properties and applications of these materials. The development of applications for ... -
Investigating the structures and properties of DMS-selected amino acid ions
(University of Waterloo, 2020-11-06)This thesis outlines gas-phase studies of ionized amino acids in which their structures and interactions within ion cluster complexes are probed using mass spectrometry, differential ion mobility, and laser spectroscopy. ... -
Risk associated with H2S evolution in sour aquifers during CO2 injection
(Elsevier, 2011)Many aquifers suitable for CO2 sequestration contain measurable concentration of dissolved non-hydrocarbon species. In this paper, the compositional modelling of the CO2 injection into aquifers that contain dissolved ... -
Feasibility of Injecting Large Volumes of CO2 into Aquifers
(Elsevier, 2009-02)Although it is recognized that deep aquifers offer a very large potential storage capacity for CO2 sequestration it is not clear how to fill the storage with a large volume of CO2 in a relatively short period of time. The ... -
Analytical Approach for Modeling of Multi Well CO2 Injection
(Elsevier, 2016-11-14)Disposal of carbon dioxide (CO2) into underground geological formations is considered a viable strategy for the mitigation of global warming. It aims to reduce greenhouse gases emitted from point sources such as power ... -
Unravelling the factors that drive separation in differential mobility spectrometry: A case study of regioisomeric phosphatidylcholine adducts
(Elsevier, 2019-10)Differential mobility spectrometry (DMS) has shown promise as an analytical tool in the field of lipidomics. However, the underlying mechanism that drives DMS-based lipid separations is still somewhat unclear. Here, we ... -
Early-Stage Incorporation Strategy for Regioselective Labeling of Peptides using the 2-Cyanobenzothiazole/1,2-Aminothiol Bioorthogonal Click Reaction
(Wiley, 2018-03)Herein, we describe a synthetic strategy for the regioselective labeling of peptides by using a bioorthogonal click reaction between 2‐cyanobenzothiazole (CBT) and a 1,2‐aminothiol moiety. This methodology allows for the ... -
A Flexible Synthesis of 68Ga-Labeled Carbonic Anhydrase IX (CAIX)-Targeted Molecules via CBT/1,2-Aminothiol Click Reaction
(MDPI, 2018-12-21)We herein describe a flexible synthesis of a small library of 68Ga-labeled CAIX-targeted molecules via an orthogonal 2-cyanobenzothiazole (CBT)/1,2-aminothiol click reaction. Three novel CBT-functionalized chelators (1–3) ... -
The structures and properties of anionic tryptophan complexes
(Royal Society of Chemistry, 2018)The physicochemical properties of [Trpn–H]− and [Trpn⋯Cl]− (n = 1, 2) have been investigated in a combined computational and experimental infrared multiple dissociation (IRMPD) study. IRMPD spectra within the 850–1900 cm−1 ... -
A parallelized molecular collision cross section package with optimized accuracy and efficiency
(Royal Society of Chemistry, 2019)Ion mobility-based separation prior to mass spectrometry has become an invaluable tool in the structural elucidation of gas-phase ions and in the characterization of complex mixtures. Application of ion mobility to structural ... -
Determination of the relationship between vancomycin trough concentrations and the AUC/MIC Dosing
(University of Waterloo, 2020-07-15)Rationale: The recently revised guidelines for the therapeutic monitoring of vancomycin recommend targeting an AUC/MIC of 400-600 for serious methicillin-resistant Staphylococcus aureus (MRSA) infections. The feasibility ... -
Risk and Benefit of Warfarin for Primary Prevention in Atrial Fibrillation Patients on Hemodialysis: A Retrospective Pilot Study
(University of Waterloo, 2020-07-17)Background Despite increased awareness and advocacy regarding the opioid epidemic, data from Health Quality Ontario (HQO) shows steady prescribing of opioids with concerning trends toward prescribing more potent opioids. ... -
The influences of spatially variable rainfall and localized infiltration on groundwater recharge in a water management context
(University of Waterloo, 2020-10-27)Water management involves monitoring, predicting, and stewarding the quality and quantity of groundwater recharge at the watershed scale. Recharge sustains baseflow to streams and replenishes water extracted by pumping at ... -
How Hot Are Your Ions in Differential Mobility Spectrometry?
(American Chemical Society, 2020-01)Ions can experience significant field-induced heating in a differential mobility cell. To investigate this phenomenon, the fragmentation of several para-substituted benzylpyridinium “thermometer” ions (R = OMe, Me, F, Cl, ... -
Augmenting Basin-Hopping With Techniques From Unsupervised Machine Learning: Applications in Spectroscopy and Ion Mobility
(Frontiers, 2019-08-07)Evolutionary algorithms such as the basin-hopping (BH) algorithm have proven to be useful for difficult non-linear optimization problems with multiple modalities and variables. Applications of these algorithms range from ... -
The structures and properties of proton- and alkali-bound cysteine dimers
(Royal Society of Chemistry, 2016)The proton-, lithium-, and sodium-bound cysteine dimers have been investigated in a joint computational and experimental infrared multiple photon dissociation (IRMPD) study. IRMPD spectra in the 1000–2000 cm−1 region show ... -
Using differential mobility spectrometry to measure ion solvation: An examination of the roles of solvents and ionic structures in separating quinoline-based drugs
(Royal Society of Chemistry, 2015)Understanding the mechanisms and energetics of ion solvation is critical in many scientific areas. Here, we present a methodlogy for studying ion solvation using differential mobility spectrometry (DMS) coupled to mass ... -
Synthesis and Reactivity of Aryl(trifluoromethyl)diazomethane Compounds
(University of Waterloo, 2020-10-26)Fluorine has a prominent role in organic chemistry and the pharmaceutical industry due to the unique properties it imparts. Naturally, trifluoromethyl groups (CF3) share similar qualities and many methods have been developed ...
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