Browsing Chemistry by Title
Now showing items 192-211 of 842
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Development and biomedical applications of solid phase micro-extraction (bio-SPME) chemical biopsy devices
(University of Waterloo, 2024-02-22)Micro-sampling is a vital component in modern diagnostics and personalized medicine. In vivo SPME is a novel branch of biomedical applications of SPME (Bio-SPME) that offers unique advantages complementary to existing ... -
Development and characterization of a laminar aerosol flow tube
(AIP, 2006-03)We have developed a new laminar aerosol flow tube (AFT) to study transformations such as ice nucleation, deliquescence, and efflorescence in model atmospheric aerosols. The apparatus consists of four sections which can be ... -
Development and optimization of coated blade spray - mass spectrometry for bioanalytical and clinical applications
(University of Waterloo, 2018-08-23)Bioanalysis is a sub-discipline of analytical chemistry that focuses on the identification and quantification of small and large molecules (e.g. metabolites and proteins) present in biological sample matrices (e.g. blood, ... -
Development and Study of the Microfluidic Open Interface Coupled with Solid-phase Microextraction for Rapid Analysis
(University of Waterloo, 2022-09-28)Analytical chemistry mainly aims to identify and quantify analytes in matrices of interest. Analytical chemistry is an indispensable part of chemistry (and other scientific fields) because identification and quantification ... -
Development and validation of a fully automated solid phase microextraction high throughput method for quantitative analysis of multiresidue veterinary drugs in chicken tissue
(Elsevier, 2019-05-16)This paper presents the development and validation of a fully automated, high-throughput multiclass, multiresidue method for quantitative analysis of 77 veterinary drugs in chicken muscle via direct immersion solid phase ... -
Development and validation of eco-friendly strategies based on thin film microextraction for water analysis
(Elsevier, 2018-12-07)The aim of the current study is the establishment of Green Analytical Chemistry strategies for water analysis by elimination/reduction of hazardous chemicals, energy consumption, and waste generation throughout the entire ... -
Development of 3D Printable, Hydrophilic, and Rapidly Curing Silicone-based Ink Formulations for Various Biomedical Applications
(University of Waterloo, 2023-01-18)3D printing is the use of additive manufacturing techniques to deposit materials layer-by-layer. Compared to alternative tissue fabrication methods such as casting, 3D printing is unique, because it uses CT and MRI scans ... -
Development of a Carbon Mesh Supported Thin Film Microextraction Membrane As a Means to Lower the Detection Limits of Benchtop and Portable GC/MS Instrumentation
(American Chemical Society, 2015-12-18)In this work, a durable and easy to handle thin film microextraction (TFME) device is reported. The membrane is comprised of poly(divinylbenzene) (DVB) resin particles suspended in a high-density polydimethylsiloxane (PDMS) ... -
Development of a Cost-Effective and Consumable-Free Interface for Comprehensive Two-Dimensional Gas Chromatography (GC×GC)
(University of Waterloo, 2007-05-23)The biggest limitation to conventional gas chromatography (GC) is limited peak capacity, making the analysis of complex mixtures a difficult or even impossible task. Comprehensive two-dimensional gas chromatography (GC×GC) ... -
Development of a Hybrid Hydrogel Bio-ink for 3D Printing of Biomimetic Tissue Constructs
(University of Waterloo, 2019-05-24)Colorectal cancer is the 2nd most common form of cancer in Canada. Most colorectal cancer deaths are caused by complications that stem from the metastasis of colorectal cancer to other organs such as the liver. During ... -
Development of a Microfluidic Hemodialysis Device Equipped with an Antifouling Nanoporous Dialysis Membrane
(University of Waterloo, 2021-06-08)This thesis presents a microfluidic hemodialyzer and an experimental platform and demonstrates that the performance of a polycarbonate membrane used in a continuous setting that can be comparable to commercial hollow-fibre ... -
Development of a multichannel microfluidic system with Schlieren imaging microscopy for online chip-based moving boundary electrophoresis
(Elsevier, 2017-02-10)The concentration gradient detection method based on the Schlieren optics employed for electrophoresis analyses by extending the technology to a multi-channel system using a prototyped microfluidic chip (thinXXS Micro-technology, ... -
Development of a Single-Stage Modulator for Comprehensive Two-Dimensional Gas Chromatography (GC × GC)
(University of Waterloo, 2011-02-22)The ability to effectively analyze particulate matter (PM2.5) in air is becoming increasingly pertinent. Allen Goldstein of the University of California in Berkeley is studying the semi-volatile fraction of organic compounds ... -
Development of Advanced Polymer-Soil Composites as High-Performance Construction Materials
(University of Waterloo, 2023-01-23)Construction using earth materials is an old building practice that can be traced back to approximately 10,000 BC. Costs for this type of construction are low because local materials are utilized, and structures are built ... -
Development of an Automatic Code Generator and Implementation of Multireference Equation of Motion Coupled-Cluster Theory in the ORCA Program Package
(University of Waterloo, 2015-10-01)Over the past 50 years, single-reference coupled-cluster theory has emerged as a cornerstone of quantum chemistry. While it is an accurate methodology for the calculation of the properties of the electronic states of many ... -
Development of Cobalt-Doped Nickel Hydroxide Sol-Gel Catalysts for Enhanced Electro-Oxidation of Urea
(University of Waterloo, 2021-05-14)Electrochemical oxidation of urea provides an approach to prevent excess urea emissions into the environment while generating value by capturing chemical energy from waste. Unfortunately, the source of high catalytic ... -
Development of Expression Systems for Various Forms of Human Nitric Oxide Synthase Isozymes
(University of Waterloo, 2015-01-23)Nitric oxide (NO) is one of the important biological molecules which has functions in neurotransmission, vasodilation, and immune responses. However, excess levels of NO have been associated with neurodegenerative and ... -
Development of Field Portable Solid Phase Microextraction Samplers for Performing On-site Environmental Analysis
(University of Waterloo, 2018-04-30)Since being introduced in 1989 solid phase microextraction (SPME) techniques have continually evolved from within the analytical chemistry community due in large part to their clean, portable and easy to handle design. It ... -
Development of HPLC-FID Coupling Using Water as the Eluent
(University of Waterloo, 2011-01-24)The characterization of all components of pharmaceutical preparations, especially in the analysis of impurities present at levels higher than 0.05% of the main component, is a challenge in the pharmaceutical industry because ... -
Development of Hydroarylation and Dehydration Methods for Conjugated Polymers
(University of Waterloo, 2017-09-28)Conjugated polymers represent an important next step for solar cell, field effect transistor, and light emitting diode technologies. However, there are several drawbacks to the current syntheses of this class of polymer ...