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Wastewater to clinical case (WC) ratio of COVID-19 identifies insufficient clinical testing, onset of new variants of concern and population immunity in urban communities

D'Aoust, Patrick M.; Tian, Xin; Towhid, Syeda Tasneem; Xiao, Amy; Mercier, Elisabeth; Hegazy, Nada; Jia, Jian-Jun; Wan, Shen; Kabir, Md Pervez; Fang, Wanting; Fuzzen, Meghan; Hasing, Maria; Yang, Minqing Ivy; Sun, Jianxian; Plaza-Diaz, Julio; Zhang, Zhihao; Cowan, Aaron; Eid, Walaa; Stephenson, Sean; Servos, Mark. R.; Wade, Matthew J.; MacKenzie, Alex E.; Peng, Hui; Edwards, Elizabeth A.; Alm, Eric J.; Graber, Tyson E.; Delatolla, Robert (medRxiv, 2022-04-20)

Clinical testing has been the cornerstone of public health monitoring and infection control efforts in communities throughout the COVID-19 pandemic. With the extant and anticipated reduction of clinical testing as the ...