Browsing Chemistry by Title
Now showing items 297-316 of 826
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Fabrication of 3D Hybrid Architectures Composed of sp2-Carbon and Inorganic Materials
(University of Waterloo, 2013-10-15)Three dimensional (3D) hybrid architectures are new types of materials that have a number of technological applications. However, the synthesis of such materials has been problematic to date. The objective of this study ... -
A facile and fully automated on-fiber derivatization protocol for direct analysis of short-chain aliphatic amines using a matrix compatible solid-phase microextraction coating
(Elsevier, 2017-07-29)Solid-phase microextraction (SPME) analysis of short-chain aliphatic amines (C-3-C-6) in aqueous solutions was investigated using pentafluorobenzaldehyde (PFBAY) as on-fiber derivatization reagent. A standard gas generating ... -
Fast assembly of non-thiolated DNA on gold surface at lower pH
(Elsevier, 2013-12-01)In a typical protocol for attaching DNA to a gold electrode, thiolated DNA is incubated with the electrode at neutral pH overnight. Here we report fast adsorption of non-thiolated DNA oligomers on gold electrodes at acidic ... -
Fast Molecular Beacon Hybridization in Organic Solvents with Improved Target Specificity
(American Chemical Society, 2010-12-02)DNA hybridization is of tremendous importance in biology, bionanotechnology, and biophysics. Molecular beacons are engineered DNA hairpins with a fluorophore and a quencher labeled on each of the two ends. A target DNA can ... -
Fast pH-assisted functionalization of silver nanoparticles with monothiolated DNA
(Royal Society of Chemistry, 2012-10-18)Attaching monothiolated DNA to silver nanoparticles has been achieved at pH 3.0 in 30 minutes and difficulties associated with DNA attachment to AgNPs at neutral pH have been revealed by studying DNA adsorption kinetics. -
Fast quantitation of opioid isomers in human plasma by differential mobility spectrometry/mass spectrometry via SPME/open-port probe sampling interface
(Elsevier, 2017-10-23)Mass spectrometry (MS) based quantitative approaches typically require a thorough sample clean-up and a decent chromatographic step in order to achieve needed figures of merit. However, in most cases, such processes are ... -
Fast Quantitation of Target Analytes in Small Volumes of Complex Samples by Matrix-Compatible Solid-Phase Microextraction Devices
(Wiley, 2017-06-20)Herein we report the development of solid-phase microextraction (SPME) devices designed to perform fast extraction/enrichment of target analytes present in small volumes of complex matrices (i.e. V <= 10 mu L). Micro-sampling ... -
A Feynman Path Centroid Effective Potential Approach for the Study of Low Temperature Parahydrogen Clusters and Droplets
(University of Waterloo, 2012-08-20)The quantum simulation of large molecular systems is a formidable task. We explore the use of effective potentials based on the Feynman path centroid variable in order to simulate large quantum clusters at a reduced ... -
Field Analysis of Total PCBs in Soils by Thermal Desorption/GC and Determination of the Individual PCB Congeners by GC X GC - TOF-MS
(University of Waterloo, 2009-01-19)Environmental field analysis provides advantages that allow real-time decisions, interactive sampling and cost effective solutions to the problems faced at the time of investigation. Gas chromatography (GC), a widespread ... -
First Principles Simulations of Vibrationally Resolved Photodetachment Spectra of Select Biradicals
(University of Waterloo, 2012-09-10)Nonadiabatic dynamical processes are ubiquitous in chemistry and biology. Such events are directly connected to the treatment of energetically close lying states which gives rise to strong vibronic interactions in which ... -
A Flexible Synthesis of 68Ga-Labeled Carbonic Anhydrase IX (CAIX)-Targeted Molecules via CBT/1,2-Aminothiol Click Reaction
(MDPI, 2018-12-21)We herein describe a flexible synthesis of a small library of 68Ga-labeled CAIX-targeted molecules via an orthogonal 2-cyanobenzothiazole (CBT)/1,2-aminothiol click reaction. Three novel CBT-functionalized chelators (1–3) ... -
Flow Cytometry-Assisted Detection of Adenosine in Serum with an Immobilized Aptamer Sensor
(American Chemical Society, 2010-05-15)Aptamers are single-stranded nucleic acids that can selectively bind to essentially any molecule of choice. Because of their high stability, low cost, ease of modification, and availability through selection, aptamers hold ... -
Fluorescent sensors using DNA-functionalized graphene oxide
(Springer, 2014-07-02)In the past few years, graphene oxide (GO) has emerged as a unique platform for developing DNA-based biosensors, given the DNA adsorption and fluorescence-quenching properties of GO. Adsorbed DNA probes can be desorbed ... -
Fluorescently Labeled Latex Particles to Monitor Film Formation
(University of Waterloo, 2017-10-25)The influence of the length of an oligo(ethylene glycol) spacer (EGn, where n is the number of ethylene glycol units) in a 1-pyrenemethoxy-EGn methacrylate (PyEG-MA) monomer on the incorporation of the monomer into a ... -
Folding and Stability Studies on Amyotrophic Lateral Sclerosis-Associated apo Cu, Zn Superoxide dismutases
(University of Waterloo, 2009-10-05)Amyotrophic lateral sclerosis (ALS) is a debilitating, incurable, neurodegenerative disease characterized by degradation of motor neurons leading to paralysis and ultimately death in ~3-5 years. Approximately 10% of ALS ... -
Fourier Transform Spectroscopy of Selected Transient Species
(University of Waterloo, 2003)The procedures and results of experimental and/or theoretical studies of four transient molecules, GeO, WO, BeH, and MgH are reported in the thesis. Two of them, GeO and WO, are diatomic molecules composed of relatively ... -
Förster Resonance Energy Transfer Mediated White-Light-Emitting Rhodamine Fluorophore Derivatives-Gamma Phase Gallium Oxide Nanostructures
(University of Waterloo, 2012-09-26)The global lighting source energy consumption accounts for about 22% of the total electricity generated. New high-efficiency solid-state light sources are needed to reduce the ever increasing demand for energy. Single-phased ... -
Freezing and Optical Properties of Model Atmospheric Aerosols
(University of Waterloo, 2007-11-20)The freezing of model atmospheric aerosols – specifically, model cirrus cloud particles – was investigated through laboratory studies of supercooled water aerosols. Water droplets with radii of 1 – 2.7 µm were exposed to ... -
From Peptides to Proteins: Exploring Modular Evolution Through the Beta-Trefoil Fold
(University of Waterloo, 2010-01-25)Understanding the origin of protein folds, and the mechanism by which evolution has generated them, is a critically important step on a path towards rational protein design. Modifying existing proteins and designing our ... -
Functional Characterization of Arcanobacterium pyogenes Pyolysin in an Oligomeric Form, and the Binding of CAMP Factor to IgG.
(University of Waterloo, 2007-12-04)The work described in this thesis deals with two pore forming toxins, namely Arcanobacterium pyogenes pyolysin and Streptococcus agalactiae CAMP factor. Pyolysin (PLO) belongs to the homologous group of cholesterol-dependent ...