Browsing Chemistry by Title
Now showing items 767-786 of 826
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Tandem DNAzymes for mRNA cleavage: choice of enzyme, metal ions and the antisense effect
(Elsevier, 2015-04-01)The concept of DNAzyme-based gene silencing via mRNA cleavage was proposed over twenty years ago. A number of studies regarding intracellular gene silencing have been reported as well. However, questions have been raised ... -
Tandem Phosphorothioate Modifications for DNA Adsorption Strength and Polarity Control on Gold Nanoparticles
(American Chemical Society, 2014-09-10)Unmodified DNA was recently used to functionalize gold nanoparticles via DNA base adsorption. Compared to thiolated DNA, however, the application of unmodified DNA is limited by the lack of sequence generality, adsorption ... -
Temperature Programming of the Second Dimension in Comprehensive Two-Dimensional Gas Chromatography (GC×GC)
(University of Waterloo, 2023-04-10)Comprehensive two-dimensional gas chromatography (GC×GC) is a mature separation technique that is now over three decades old. It separates all sample components using two GC columns with different selectivities, connected ... -
Temperature Response of Aqueous Solutions of Pyrene End-Labeled Poly(N-isopropyl acrylamide)s Probed by Steady-State and Time-Resolved Fluorescence
(Wiley, 2018-02-15)Aqueous solutions of a series of monodisperse poly(N‐isopropylacrylamide)s end‐labeled with n‐butyl‐1‐pyrene at one or both chain ends (Pyn‐PNIPAMs with n = 1 or 2) were studied by turbidimetry, light scattering, and ... -
Temperature-Controlled Interactions Between Poly(N-isopropylacrylamide) Mesoglobules Probed by Fluorescence
(American Chemical Society, 2018-02-23)Temperature-Controlled Interactions Between Poly(N-isopropylacrylamide) Mesoglobules Probed by Fluorescence Michael Andrew Fowlera, Jean Duhamel*a a Institute for Polymer Research, Waterloo Institute for Nanotechnology, ... -
Templated Synthesis of Magnetic Nanoparticles through the Self-Assembly of Polymers and Surfactants
(Multidisciplinary Digital Publishing Institute, 2014-08-04)The synthesis of superparamagnetic nanoparticles (NPs) for various technological applications continues to be an interesting research topic. The successful application of superparamagnetic NPs to each specific area typically ... -
The tertiary amide and carbamoyloxy groups in aromatic directed metalation synthesis of polysubstituted benzene and pyridine derivatives
(University of Waterloo, 2014-06-04)Includes bibliographical references. -
Thallium Tellurides as Thermoelectrics
(University of Waterloo, 2015-12-11)Noting the steadily worsening problem of depleted fossil fuel sources, alternate energy sources become increasingly important, such as thermoelectrics that may use waste heat to generate electricity. To be economically ... -
Therapeutic drug monitoring, clinical metabolomics and pharmacometabolomics via solid phase microextraction (SPME): The first step towards an alternative rapid diagnostic tool
(University of Waterloo, 2020-05-20)Personalized medicine is a branch of medicine that focuses on how a prescribed therapeutic treatment affects a specific individual as opposed to its general effects for the broader population. The goal of personalized ... -
Thermal cis-to-trans isomerization mechanism of N-(phenylazo)-substituted nitrogen heterocycles
(University of Waterloo, 2008-12-10)Triazenes, compounds containing a diazoamino moiety (–N(1)=N(2)–N(3)<), are known for their reversible cis-trans isomerization character and hence, have the potential to be used in photoswitchable devices and photostorage ... -
Thermal evolution of simple amino acids (glycine and alanine) on non-crystalline and polycrystalline ice studied by Reflection-Absorption Infrared Spectroscopy
(University of Waterloo, 2009-05-21)The behaviour of glycine and alanine, deposited under ultrahigh vacuum conditions onto non-crystalline ice (NCI) and polycrystalline ice (PCI) has been studied using Reflection-Absorption Infrared Spectroscopy (RAIRS). The ... -
Thermal Interface Materials (TIM) for Applications in Microelectronics
(University of Waterloo, 2012-08-31)A major challenge in the formulation of thermal interface materials (TIM), used in the microelectronics industry to facilitate heat transfer from an electronic package to a heat sink, is to ensure that the material is ... -
A Thermochemical Investigation of Gas Phase Anionic Nucleobase Complexes by Infrared Multiple Photon Dissociation Spectroscopy and Electronic Structure Calculations
(University of Waterloo, 2021-05-21)In this thesis, a computational and experimental investigation of gas phase cation-molecule complexes has been undertaken to analyse the gas phase clustering behaviour of biologically relevant cyclic anionic species. ... -
The Thermochemistry of Protonated and Sodiated Clusters Investigated via High-Pressure Mass Spectrometry
(University of Waterloo, 2007-09-27)High-pressure mass spectrometry has been employed to investigate hydrogen and sodium bound ion-molecule complexes in the gas phase. Insight into the structure and reactivity of ion-molecule complexes has been gained by ... -
Thermodynamic Investigation of Human Nitric Oxide Synthase: Enzyme-Inhibitor Interactions
(University of Waterloo, 2012-01-20)Nitric oxide (NO) is produced in different mammalian tissues by nitric oxide synthase (NOS), which has three isoforms: neuronal NOS (nNOS), endothelial NOS (eNOS), and inducible NOS (iNOS). All NOS isoforms contain two ... -
Thermodynamics and Kinetics of Adaptive Binding in the Malachite Green RNA Aptamer
(American Chemical Society, 2013-09-24)Adaptive binding, the ability of molecules to fold themselves around the structure of a ligand and thereby incorporating it into their three-dimensional fold, is a key feature of most RNA aptamers. The malachite green ... -
Thermodynamics, kinetics and inclusion body formation of a de novo designed protein Threefoil
(University of Waterloo, 2014-01-28)Threefoil is a small engineered protein of 141 amino acids which is a member of the beta-trefoil superfamily, with three-fold symmetry and high thermal and kinetic stability. Its primary sequence was designed based on a ... -
Thermoelectric Materials: Ternary and Higher Oxides and Tellurides
(University of Waterloo, 2010-01-05)Thermoelectric power generators can convert a temperature gradient into electrical energy, serving as a new energy resource by utilizing solar energy or by utilizing more waste heat. Thermoelectric coolers have the advantage ... -
Thermoelectric Properties and Stability of Barium Copper Chalcogenides
(University of Waterloo, 2019-09-25)The objective of this thesis was to study the thermoelectric properties of copper chalcogenide-based materials with mixed chalcogen atom sites. Herein, the effect of different concentrations of chalcogen atoms on the ... -
Thermoelectric Properties of Ti₀.₅Zr₀.₂₅Hf₀.₂₅CoₓNi₁₋ₓSn, Ti₀.₅Zr₀.₂₅Hf₀.₂₅NiSn₁₋ₓSbₓ Half-Heusler Alloys
(University of Waterloo, 2016-06-17)Energy is essential in today’s world as it is used in society on a day to day basis for a variety of applications. However, more than half of the energy produced in the world today is wasted as heat. Due to the climate ...