Browsing Chemistry by Title
Now showing items 157-176 of 826
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Daptomycin forms cation- and size-selective pores in model membranes
(Elsevier, 2014-10)Daptomycin is a lipopeptide antibiotic that is used clinically to treat severe infections caused by Gram-positive bacteria. Its bactericidal action involves the calcium-dependent binding to membranes containing ... -
Daptomycin: Mechanism of Action and Bacterial Resistance
(University of Waterloo, 2015-02-25)Daptomycin is an important lipopeptide antibiotic used for treating severe infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus ... -
Daptomycin: studies on its action mode and on bacterial resistance with model membranes
(University of Waterloo, 2016-05-16)Bacterial resistance to antibiotics is one of the most serious problems facing medicine today. Recently, reports have appeared describing bacteria that are resistant to daptomycin (dap), an important antibiotic used against ... -
Defect Investigation on Hematite Photoanodes
(University of Waterloo, 2023-05-17)Efforts to improve the efficiency of photoelectrocatalytic reactions on hematite photoanodes routinely focus on the analysis of photophysics, or on the fabrication of complex material architectures. The discontinuity of ... -
Defect-Rich Size-Selected Nanoclusters and Nanocrystalline Films of Titanium (IV) Oxide and Tantalum (IV) Oxide for Efficient Photocatalyst and Electroforming-Free Memristor Applications
(University of Waterloo, 2016-05-16)Transition metal oxides, TiO2 and Ta2O5, are two of the most extensively studied wide bandgap semiconductor materials (with high work functions). Due to their suitable band edge positions for hydrogen evolution and exceptional ... -
Defect-rich Titanium (IV) Oxide and Zirconium (IV) Oxide Nanostructures for Ultra-efficient Photocatalyst and High-Tc Dilute Ferromagnetic Semiconductor Applications
(University of Waterloo, 2016-05-16)In transparent conductive oxide nanostructures, oxygen vacancy defects (neutral, singly charged, and doubly charged defects) are found to be one of the most important and prevalent defects due to the enhancement of light ... -
Degradable starch nanoparticle assisted ethanol precipitation of DNA
(Elsevier, 2014-04-18)Precipitation of DNA from a large volume of aqueous solution is an important step in many molecular biology and analytical chemistry experiments. Currently, this is mainly achieved by ethanol precipitation, where a long-term ... -
Demonstration and Validation of the Use of Passive Samplers for Monitoring Soil Vapor Intrusion to Indoor Air
(University of Waterloo, 2014-08-18)This thesis documents a demonstration/validation of passive diffusive samplers for assessing soil vapor, indoor air and outdoor air concentrations of volatile organic compounds (VOCs) at sites with potential human health ... -
Density Functional Theory Calculations on the Sorption of Organoarsenicals onto Hydrated Iron (III) Oxyhydroxide Clusters
(University of Waterloo, 2017-01-23)Organic forms of arsenic are introduced into the environment by natural and anthropogenic processes and they pose a threat to human health. The fate of these pollutants depends on their interactions with reactive soils ... -
Depletion gels from dense soft colloids: Rheology and thermoreversible melting
(American Institute of Physics, 2014-08-01)Upon addition of small nonadsorbing linear polymers, colloidal glasses composed of large hard spheres melt and eventually revitrify into the so-called attractive glass regime. We show that, when replacing the hard spheres ... -
Design and Fabrication of a Nanofluidic Cell System for High-Resolution Electron Microscopy of in-Liquid Samples.
(University of Waterloo, 2017-08-15)The transmission electron microscope (TEM) has been an important characterization tool since its invention in 1932.[1] The ability to achieve atomic resolution imaging and collect real-time movies, combined with the ... -
Design of efficient block-sparse data structures and associated tensor multiplications for applications in Cluster in Molecule electronic structure calculations
(University of Waterloo, 2022-08-18)The Cluster-in-molecule approach (CiM) is one of the most popular methods in electronic structure calculations for medium to large molecules and systems. The Nooijen group is currently developing a new CiM approach using ... -
Design, characterization, optical and photophysical properties of novel thiophene monomers and polymers containing pyrene moieties linked via rigid and flexible spacers
(Elsevier, 2019-02-01)Herein, we report the synthesis of three novel thiophene monomers connected to pyrene moieties via a flexible oligo(ethylene glycol) (OEG) spacer with an oxygen -to-pyrene (T1), a flexible OEG spacer with an oxygen ... -
Design, Synthesis and Characterization of a Series of Self-assembling Polypeptides
(University of Waterloo, 2007-05-24)A series of polypeptides with well-defined sequences, (Asp3Phe1)n, (Asp2Phe1)n, (Asp1Phe1)n, (Asp1Phe2)n, and (Asp1Phe3)n, containing the hydrophilic amino acid, aspartic acid (Asp) and the hydrophobic amino acid, phenylalanine ... -
Design, synthesis, and evaluation of inhibitors of steroid sulfatase
(University of Waterloo, 2014-04-22)Steroid sulfatase (STS) catalyzes the desulfation of biologically inactive sulfated steroids to yield biologically active desulfated steroids and is currently being examined as a target for therapeutic intervention for the ... -
Desulfurization Activated Phosphorothioate DNAzyme for the Detection of Thallium
(American Chemical Society, 2015-10-20)Thallium (Tl) is a highly toxic heavy metal situated between mercury and lead in the periodic table. While its neighbors have been thoroughly studied for DNA-based sensing, little is known about thallium detection. In this ... -
Detection of Nitroaromatic Compounds through Fluorescence Quenching of Pyrene Labeled Starch Nanoparticles
(University of Waterloo, 2018-12-10)The aim of this research was to demonstrate the potential application of starch nanoparticles (SNPs) labeled with 1-pyrenebutyric acid (PBA) as the active component in optical sensors used for the detection of minute ... -
Detection of Nitroaromatics Using the Excimer Fluorescence of Pyrene-Labeled Starch Nanoparticles
(American Chemical Society, 2019-09-09)Starch nanoparticles (SNPs) were hydrophobically modified using 1-pyrenebutyric acid (PyBA) with degrees of substitution (DS) between 0.0006 and 0.11. Fluorescence quenching studies were conducted on the pyrene-labeled ... -
Determination of Geosmin and 2-Methylisoborneol in Fish using In-vivo Solid Phase Microextraction
(University of Waterloo, 2012-08-31)The presence of off-flavor compounds in fish represents one of the significant economic problems encountered in aquaculture. These off-flavor compounds are due to the absorption of substances produced by microorganisms. ... -
Determination of Polycyclic Aromatic Hydrocarbons in Sediment by Pressure-Balanced Cold Fiber Solid Phase Microextraction
(American Chemical Society, 2017-09-20)An improved performance of the cold fiber solid phase micro extraction (CF-SPME) technique was accomplished with the use of the pressure balanced procedure. In order to obtain a pressure-balanced state during extraction ...