Chemistry
This is the collection for the University of Waterloo's Department of Chemistry .
Research outputs are organized by type (eg. Master Thesis, Article, Conference Paper).
Waterloo faculty, students, and staff can contact us or visit the UWSpace guide to learn more about depositing their research.
Recent deposits
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Controlled nanometer liquid layer thicknesses for the study of nanomaterials and biospecimens in liquid-cell transmission electron microscopy
(University of Waterloo, 2023-09-22)Liquid-cell transmission electron microscopy (LC-TEM) is an in-situ microscopy technique which aims to image nanomaterials and biospecimens in their native liquid phase environment. To accomplish this task, miniature vessels ... -
Investigation of the Electronic Structure and Magnetic Properties of CeO2-X
(University of Waterloo, 2023-09-19)In literature, it has been reported that undoped CeO2 exhibits a room-temperature ferromagnetic-like ordering that does not follow Curie-type behaviour, typically found in magnetic materials. However, none of the proposed ... -
Towards Understanding Differential Ion Mobility and its Applications for Analytical and Medicinal Chemistry
(University of Waterloo, 2023-08-30)This PhD thesis, titled “Towards Understanding Differential Ion Mobility Spectrometry and its Applications in Analytical and Medicinal Chemistry,” encompasses a broad effort to understand the principles that underpin ... -
Improving Biospecimen Imaging in Liquid Phase Electron Microscopy
(University of Waterloo, 2023-08-24)This thesis highlights the progress made in LPEM and the study of biosamples. The introduction provides a comprehensive overview of the challenges encountered in investigating molecular processes and traces the historical ... -
Selection and characterization of an aptamer to a thiazole orange derivative for use in a fluorescence-based biosensor
(University of Waterloo, 2023-08-18)Aptamers are short single-stranded DNA or RNA sequences that have been selected in vitro to have a high binding affinity to a specific target molecule. One class of aptamers can bind to small non-fluorescent molecules to ... -
Electroorganic CO₂ Fixation Via Paired Electrolysis and Nanoscale Electrocatalysis
(University of Waterloo, 2023-08-17)Sustainable energy driven electroorganic synthesis provides a green and inexpensive alternative to traditional synthetic approaches. For instance, the electroreduction of many classes of organic molecules enables the ... -
Biochemical Characterization and Optimization of RNA Aptamers Bound to Hoechst Dye Derivatives
(University of Waterloo, 2023-08-09)Ribonucleic acid (RNA) aptamers are single-stranded nucleic acids that are typically selected through a process known as Systematic Evolution of Ligands by EXponential Enrichment (SELEX). These oligonucleotides can bind ... -
Solid Solution Tetrelides and Pnictides for Thermoelectric Applications
(University of Waterloo, 2023-07-17)Recent major advancements in thermoelectric material performance center around the development and understanding of band structure engineering techniques and phonon scattering mechanisms. Solid solution materials have the ... -
Defect Investigation on Hematite Photoanodes
(University of Waterloo, 2023-05-17)Efforts to improve the efficiency of photoelectrocatalytic reactions on hematite photoanodes routinely focus on the analysis of photophysics, or on the fabrication of complex material architectures. The discontinuity of ... -
Solid phase microextraction: a versatile technique for lipid analysis
(University of Waterloo, 2023-04-26)Extensive multidisciplinary research and improvements to instrumentation and workflows are continuously enabling new insights into the role of lipids in health and disease. As with other metabolites, the accurate analysis ... -
Aptamer-Based Detection of Caffeine and Theophylline Through Utilization of Gold Nanoparticles and Graphene Oxide
(University of Waterloo, 2023-04-26)The caffeine and theophylline aptamers were used in tandem with gold nanoparticles and graphene oxide to study potential methods for small molecule detection. The AuNP approach is a label-free approach, and the graphene ... -
Temperature Programming of the Second Dimension in Comprehensive Two-Dimensional Gas Chromatography (GC×GC)
(University of Waterloo, 2023-04-10)Comprehensive two-dimensional gas chromatography (GC×GC) is a mature separation technique that is now over three decades old. It separates all sample components using two GC columns with different selectivities, connected ... -
Development of the Synthesis of Thiophene and Thiazole Based Conjugated Polymers Through Direct Arylation and The Separation of Carbon Nanotubes Using Degradable Conjugated Polymers
(University of Waterloo, 2023-01-30)Conjugated polymers are an ever-growing field due to their ability to be used for a variety of purposes such as photovoltaics, field-effect transistors, light emitting diodes, and organic sensors. To further this field, ... -
Optimization of Tin Selenide Thermoelectric Properties
(University of Waterloo, 2023-01-27)The high performance thermoelectric material tin selenide is of notable interest to the field of thermoelectric materials; since breaking the record for being the most efficient thermoelectric material due to the ultralow ... -
Exploration of reconstructed PET hydrolase ancestors by biophysical and computational methods
(University of Waterloo, 2023-01-26)Ancestral sequence reconstruction (ASR), originally developed for the study of molecular evolution, has gained attention as a promising method for protein engineering in the recent decade. The ancestors revived by this ... -
Machine Learning Model for Repurposing Drugs to Target Viral Diseases
(University of Waterloo, 2023-01-26)With recent events, such as the Covid-19 pandemic, it is increasingly important to develop strategies to combat viral diseases. Due to technological advancements, computer-aided drug design and machine learning (ML)-based ... -
Immature SOD1: protein folding, misfolding and aggregation
(University of Waterloo, 2023-01-25)Protein misfolding and aggregation are hallmarks of many diseases, including amyotrophic lateral sclerosis (ALS). In familial ALS, aberrant self-association of mutant Cu,Zn-superoxide dismutase (SOD1) is implicated as a ... -
Development of Advanced Polymer-Soil Composites as High-Performance Construction Materials
(University of Waterloo, 2023-01-23)Construction using earth materials is an old building practice that can be traced back to approximately 10,000 BC. Costs for this type of construction are low because local materials are utilized, and structures are built ... -
Development of 3D Printable, Hydrophilic, and Rapidly Curing Silicone-based Ink Formulations for Various Biomedical Applications
(University of Waterloo, 2023-01-18)3D printing is the use of additive manufacturing techniques to deposit materials layer-by-layer. Compared to alternative tissue fabrication methods such as casting, 3D printing is unique, because it uses CT and MRI scans ... -
Equilibrium and dynamical computation schemes for vibronic models of nonadiabatic systems
(University of Waterloo, 2023-01-06)Two computational schemes were investigated for studying vibronic models of nonadiabatic systems: Path Integral Monte Carlo (PIMC) and vibrational electronic coupled cluster (VECC). A PIMC method was used to investigate ...
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