• Adnectin Solubility and Dynamics 

  Trainor, Kyle (University of Waterloo, 2019-10-28)

  Rapid growth of the global market for monoclonal antibodies (mAbs) has generated considerable interest in the development of alternative molecules that facilitate rapid discovery and manufacturing, while replicating the ...

• In Search of an Ideal Modulator for Comprehensive Two-Dimensional Gas Chromatography 

  Boswell, Haleigh (University of Waterloo, 2019-10-24)

  Gas chromatography has been a prevailing technique to separate different mixtures of volatile and semi-volatile compounds in order to qualitatively and quantitatively identify each individual component. With more complex ...

• Plasmonic and Magneto-Optical Properties of Nonstoichiometric Indium Nitride Nanostructures 

  Chen, Shuoyuan (University of Waterloo, 2019-10-23)

  Localized surface plasmon resonance (LSPR) in semiconductor nanostructures have attracted intense attention recently for its broad application in bio-imaging, chemical sensing, photocatalysis, and photovoltaics. Compared ...

• Crystal Structures and Optical Properties of Group 14 Chalcogenides 

  Menezes, Luke (University of Waterloo, 2019-09-26)

  The crystal structures and physical properties of several new tetrel and chalcogenide compounds have been investigated in this thesis. The crystal structures, syntheses, and electronic structures of the three centrosymmetric ...

• Determining Molecular Physicochemical Properties Using Differential Mobility Spectrometry 

  Bowman, Zachary (University of Waterloo, 2019-09-26)

  This thesis aims to explore the usage of differential mobility spectrometry (DMS) and quantum chemical calculations to separate and identify drug compounds, as well as the use of machine learning (ML) to predict physicochemical ...

• Bacteriophage M13 as a Template for Multi-Enzyme Assembly 

  Urquhart, Taylor (University of Waterloo, 2019-09-25)

  An important aspect of bionanotechnology is the utilization of biomolecules to prepare controlled and defined arrangements of multiple components with nanoscale order. Bacteriophage M13 is a filamentous phage composed of ...

• Thermoelectric Properties and Stability of Barium Copper Chalcogenides 

  Jafarzadeh, Parisa (University of Waterloo, 2019-09-25)

  The objective of this thesis was to study the thermoelectric properties of copper chalcogenide-based materials with mixed chalcogen atom sites. Herein, the effect of different concentrations of chalcogen atoms on the ...

• Characterization of Self-Assembling Quinoline- Based Foldamers by Fluorescence Anisotropy 

  Wang, Jingqi (University of Waterloo, 2019-09-24)

  Foldamers represent a family of synthetic macromolecules which, like their biological counterparts, are able to adopt a well-defined conformation in solution. Oligoquinoline-carboxamides (Qn) are a group of foldamers that ...

• Site-specific Chemistry of Sulfur-containing Amino Acids on Si(111)-√3×√3-Ag: Bioorganic Nanostructured Film Growth and Adsorbate-induced Metal Cluster Formation Governed by Surface Defects 

  Farkhondeh Borazjani, Hanieh (University of Waterloo, 2019-09-24)

  The interfacial interactions and film growth mechanisms of sulfur-containing amino acids on Si(111)-√3×√3-Ag are investigated by using x-ray photoelectron spectroscopy (XPS) and scanning tunneling microscopy (STM) at room ...

• Enhanced Diffusion in Latex Films Induced by Oligomers and Characterized by Pyrene Excimer Fluorescence 

  You, Zehou (University of Waterloo, 2019-09-24)

  Pyrene excimer fluorescence (PEF) was used to investigate the effects that the presence of low molecular weight oligo(n-butyl methacrylate) (OBMA) have on the diffusion of high molecular weight poly(n-butyl methacrylate) ...

• Investigating the Physicochemical Properties of B12X122− (X = H, F, Cl, Br, I) 

  Lim, Su Ji (University of Waterloo, 2019-09-24)

  This thesis focuses on B12X122– (X = H, F, Cl, Br, I) experimentally and computationally to understand the fundamental behaviour of this multiply charged anion (MCA) in the gas and solution phases. The thesis explores three ...

• Effective Synthesis of Iron-Carbonyl Small Rings and Macrocycles via Migratory Insertion Reactions 

  Leung, Aaron (University of Waterloo, 2019-09-23)

  Migratory insertion reactions (MIRs) of PFpR [PFp = (PPh2(CH2)3Cp)Fe(CO)2, R = (CH2)5CH3 or (CH2)4CH=CH2], which involve migratory insertion polymerization (MIP) and intramolecular migratory insertion cyclization (MIC), ...

• Protein Engineering of Microbial Ferritins 

  Gyamfi, Hawa (University of Waterloo, 2019-09-23)

  Nanotechnology has become a field of intense interest due to its applications in medicine, cosmetics, energy, and fabrics. The field has evolved to include nanodimensional self-assembling cage proteins which are multisubunit ...

• Development of Solid Phase Microextraction Methodologies for the Determination of Anthropogenic Contaminants from Fatty Food Matrices 

  Gruszecka, Dominika (University of Waterloo, 2019-09-03)

  Anthropogenic contaminants have been on the rise worldwide due to global industrialization. The world is now faced with the consequences of the pollution caused by the exposure of man-made chemicals in the environment. ...

• Hydrophobic Modification of Starch 

  Amos, Ryan (University of Waterloo, 2019-08-27)

  Starch is a very common polysaccharide with multiple applications in the industry, but the range of physical properties exhibited by that material is relatively limited due to its strongly hydrophilic character. The work ...

• Developments and applications of solid phase microextraction (SPME) coupled to direct analysis in real time (DART) and approaches towards small volume analysis 

  Vasiljevic, Tijana (University of Waterloo, 2019-08-21)

  Solid phase microextraction (SPME) has been rapidly developing since its invention in 1990. Due to a flexible design and the ability to implement various extractive coatings, SPME has found use in numerous applications. ...

• Synthesis of Molecularly Defined Conjugated Oligomers and Polymers through Dehydrative Coupling 

  Abuadas, Sara (University of Waterloo, 2019-08-21)

  The development of scalable methods for the synthesis of conjugated materials remains among the most important aspects for their integration into devices at a commercial level. Drawing inspiration from nature as well as ...

• Molecular Imprinting with Functional DNA and Nanozymes: Affinity Improvement and Selective Catalysis 

  Zhang, Zijie (University of Waterloo, 2019-08-19)

  Molecular imprinting refers to polymerization of functional monomers in the presence of a template molecule. It is a general method to prepare stable and cost-effective artificial ligands as antibody mimics (also known as ...

• Computational and Spectroscopic Investigations of Intermolecular Interactions in Clusters 

  Carr, Patrick (University of Waterloo, 2019-08-15)

  In this thesis, the study of intermolecular interactions within cluster systems is presented. Covalently and non-covalently bound clusters possess oftentimes unique and unexpected properties which can be tuned by adjustment ...

• Action Mechanism and Structural Studies on the Lipopeptide Antibiotic Daptomycin 

  Beriashvili, David (University of Waterloo, 2019-07-02)

  Daptomycin (dap) is calcium-dependent lipopeptide antibiotic that is used clinically to treat systemic infections caused by Gram-positive pathogens. It is thought that dap brings about its antimicrobial effect by binding ...

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