Browsing Chemistry by Title
Now showing items 248-267 of 826
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Early-Stage Incorporation Strategy for Regioselective Labeling of Peptides using the 2-Cyanobenzothiazole/1,2-Aminothiol Bioorthogonal Click Reaction
(Wiley, 2018-03)Herein, we describe a synthetic strategy for the regioselective labeling of peptides by using a bioorthogonal click reaction between 2‐cyanobenzothiazole (CBT) and a 1,2‐aminothiol moiety. This methodology allows for the ... -
Effect of Background Water Matrices on Pharmaceutical and Personal Care Product Removal by UV-LED/TiO2
(Multidisciplinary Digital Publishing Institute, 2021-04-30)In this study, we evaluated the effectiveness of UV-LED-irradiated TiO2 in removing 24 commonly detected PPCPs in two water matrices (municipal wastewater effluent and Suwannee River NOM–synthetic water) and compared their ... -
The effect of hematocrit on solid-phase microextraction
(Elsevier, 2018-02-25)Solid-phase microextraction (SPME) is an approach to sample preparation that has demonstrated its appropriateness for isolating/enriching analytes present in complex biofluids with minimum sample pre-treatment. Several ... -
Effect of N-Oxide Incorporation on Thiazole-Containing Conjugated Polymers
(University of Waterloo, 2018-10-24)The use of conjugated polymers (CPs) in organic electronics has been an area of continued interest over the last several years due to many advantages over their inorganic counterparts. Due to the nature of CPs, devices can ... -
Effect of pendant distribution on the dispersancy of maleated ethylene propylene
(University of Waterloo, 2011-09-30)This study describes how changes made to the modification of a polyolefin affect the solution properties of these modified polyolefins in apolar solvents. The modified polyolefins of interest are maleated ethylene-propylene ... -
Effective Synthesis of Iron-Carbonyl Small Rings and Macrocycles via Migratory Insertion Reactions
(University of Waterloo, 2019-09-23)Migratory insertion reactions (MIRs) of PFpR [PFp = (PPh2(CH2)3Cp)Fe(CO)2, R = (CH2)5CH3 or (CH2)4CH=CH2], which involve migratory insertion polymerization (MIP) and intramolecular migratory insertion cyclization (MIC), ... -
The Effects of Chemical and Physical Pressure on Heavy Atom Radicals
(University of Waterloo, 2013-10-01)Neutral radicals have been pursued as building blocks for conductive and magnetic materials for several decades. Carbon-based materials are typically plagued by dimerization and quenching of spins, but the incorporation ... -
Effects of Metal Cations and Cyclodextrins on 1,3 Diphenyltriazenes Isomerization and Decomposition
(University of Waterloo, 2009-09-18)Triazenes are molecules characterized by having the triazeno group (–N=N–N<). They are known as photoactive molecules due to trans-cis photoinduced isomerization around the N=N bond. Their nucleophilic character makes them ... -
Effects of Myristoylation on the Structure and Stability of Hisactophilin
(University of Waterloo, 2007-01-23)Hisactophilin is a histidine rich, actin binding protein from Dictyostelium discoideum. The structure of Hisactophilin, an all-beta protein, is typical of the beta-trefoil superfamily of proteins. In addition, hisactophilin ... -
Effects of Polyethylene Glycol on DNA Adsorption and Hybridization on Gold Nanoparticles and Graphene Oxide
(American Chemical Society, 2012-10-09)Understanding the interface between DNA and nanomaterials is crucial for rational design and optimization of biosensors and drug delivery systems. For detection and delivery into cells, where high concentrations of cellular ... -
An Efficient Lanthanide-Dependent DNAzyme Cleaving 2 '-5 '-Linked RNA
(Wiley, 2016-05-17)RNA can form two types of linkage. In addition to the predominant 3'-5' linkage, 2'-5'-linked RNA is also important in biology, medicine, and prebiotic studies. Here, in vitro selection was used to isolate a DNAzyme that ... -
Electrochemical Study of DNA Damage and Its Application for the Design of Carbon Nanomaterials based Combination Chemotherapy
(University of Waterloo, 2015-10-05)Cis-diamminedichloroplatinum (II) (cisplatin or CDDP) is the first platinum based chemotherapy drug used for treating various types of cancers. It is discovered that the combination of cisplatin with electron donors can ... -
Electromechanical Coupling of Graphene With Cells
(University of Waterloo, 2011-08-10)Nanomaterials have been studied extensively in the last decade in the context of many applications such as polymer composites, energy harvesting systems, sensors, ‘transparent’-like materials, field-effect transistors (FETs), ... -
The Electronic Structures of Cobalt-containing Diatomic Molecules
(University of Waterloo, 2016-09-28)Theoretical investigations of the electronic structures of several metal-containing diatomic species (i.e., Co2+, Co+•RG (RG=He, Ar, Kr), Au+Ar, and Ag+Ar) have been conducted. In this study, two categories of methods have ... -
Electroorganic CO₂ Fixation Via Paired Electrolysis and Nanoscale Electrocatalysis
(University of Waterloo, 2023-08-17)Sustainable energy driven electroorganic synthesis provides a green and inexpensive alternative to traditional synthetic approaches. For instance, the electroreduction of many classes of organic molecules enables the ... -
Electrophilic ‘Umpolung’ Cyclizations of Alkynes in the Synthesis of Polycyclic Aromatic Hydrocarbons
(University of Waterloo, 2021-05-12)Polycyclic aromatic hydrocarbons (PAHs), such as acenes and phenacenes, are important structural motifs which have found great utility in the future of electronics as organic semi-conducting materials. Reliable methods of ... -
Electrostatically Directed Visual Fluorescence Response of DNA-Functionalized Monolithic Hydrogels for Highly Sensitive Hg2+ Detection
(American Chemical Society, 2011-03-23)Hydrogels are cross-linked hydrophilic polymer networks with low optical background and high loading capacity for immobilization of biomolecules. Importantly, the property of hydrogel can be precisely controlled by changing ... -
Emergence and Spread of the SARS-CoV-2 Omicron Variant in Alberta Communities Revealed by Wastewater Monitoring
(medRxiv, 2022-10-03)Wastewater monitoring of SARS-CoV-2 allows for early detection and monitoring of COVID-19 burden in communities and can track specific variants of concern. Targeted assays enabled relative proportions of SARS-CoV-2 Omicron ... -
Enantioselective Conjugate Additions to Meldrum’s Acid Acceptors for the Synthesis of Quaternary Centres and Studies on Persistent Intramolecular C–H•••X (X = O, S, Br, Cl, and F) Hydrogen Bonds Involving Benzyl Meldrum’s Acids
(University of Waterloo, 2009-08-31)The construction of benzylic quaternary stereocentres via the enantioselective copper-catalyzed 1,4-addition of dialkylzinc reagents to Meldrum’s acid acceptors in the presence of a phosphoramidite ligand is reported. ... -
Enantioselective Rh(I)-Catalyzed Conjugate Alkynylation of 5-Benzylidene Meldrum’s Acid with TMS-acetylene
(University of Waterloo, 2009-08-27)The Rh-catalyzed conjugate addition of TMS-acetylene to alkylidene Meldrum’s acids was developed. Exceptional ee’s and yields were attained using chiral 3,5-Xylyl-BIPHEP ligand. The scope of the reaction was also shown ...