Browsing Chemistry by Title
Now showing items 80-99 of 826
-
Cage-like Proteins as Bioink Components for 3D Bioprinting
(University of Waterloo, 2018-01-24)Hydrogel matrices have been used as structural surrogates in 3D bioprinting as a mechanism to provide the appropriate environment for cell adhesion and proliferation. In this research, the preparation and optimization of ... -
Calibrant Free Sampling and Enrichment with Solid-Phase Microextraction: Computational Simulation and Experimental Verification
(American Chemical Society, 2017-04-05)Despite the benefits of diffusion-based calibrant-free sampling based on solid-phase microextraction (SPME), this quantification approach is often underestimated due to an inadequate understanding of how extraction parameters ... -
Calibrating the Long-Range Backbone Dynamics of Polymers in Solution Using Two Different Models
(University of Waterloo, 2022-09-29)The fluorescence decays of a series of 41 pyrene-labeled poly(oligo(ethylene glycol)methyl ether methacrylate)s (Py-PEGnMA where n = 0, 1, 2, 3, 4, 5, 9, 16, 19) were prepared by free-radical polymerization of 1-pyrenebutyl ... -
Calmodulin as a universal regulator of voltage gated calcium channels
(University of Waterloo, 2014-05-22)Calmodulin (CaM) is a ubiquitous calcium-binding protein responsible for the binding and activation of a vast number of enzymes and signaling pathways. It contains two lobes that bind two calcium ions each, separated by a ... -
Calmodulin Binding and Activation of Mammalian Nitric Oxide Synthases
(University of Waterloo, 2008-05-12)Calmodulin (CaM) is a ubiquitous cytosolic Ca2+-binding protein involved in the binding and regulation of more than three-hundred intracellular target proteins. CaM consists of two globular domains joined by a central ... -
Calmodulin regulates Cav3 T-type channels at their gating brake
(American Society for Biochemistry and Molecular Biology, 2017-12-08)Calcium (Cav1 and Cav2) and sodium channels possess homologous CaM-binding motifs, known as IQ motifs in their C termini, which associate with calmodulin (CaM), a universal calcium sensor. Cav3 T-type channels, which serve ... -
Capturing Plant Metabolome with Direct-Immersion in Vivo Solid Phase Microextraction of Plant Tissues
(American Chemical Society, 2015-12-15)For the first time, an in vivo sampling mode of direct immersion–solid phase microextraction (DI-SPME) was employed to capture the metabolome of living plant specimens, using apple (Malus × domestica Borkh.) as a model ... -
Carbon Nanomaterials for Nanofluidic and Membrane Applications
(University of Waterloo, 2014-12-11)The successful fabrication and characterization of carbon nanomaterials as potential next generation materials for nanofluidic and membrane applications was demonstrated by this work. Ion transport through graphene oxide ... -
Carbon Nanotubes as Versatile Devices for Detoxification and Cellular Entry
(University of Waterloo, 2012-10-30)The ability to bypass most cellular barriers to gain access to intracellular compartments has great potential in cell biology. The possibilities range from efficient delivery of macromolecules such as plasmids to small ... -
Cardiolipin Prevents Membrane Translocation and Permeabilization by Daptomycin
(American Society for Biochemistry and Molecular Biology, 2014-04-25)Daptomycin is an acidic lipopeptide antibiotic that, in the presence of calcium, forms oligomeric pores on membranes containing phosphatidylglycerol. It is clinically used against various Gram-positive bacteria such as ... -
Casting Shadow on the Photocatalytic Activity of Plasmonic Antimony Doped Tin Oxide Nanoparticles in Degrading Rhodamine 590
(University of Waterloo, 2018-06-04)Increasing the feasibility of water purification systems at the manufacturing, technical and material engineering level is an urgent matter that is of global interest. Concerning materials engineering for water purification ... -
The Catalytic Intramolecular Friedel-Crafts Acylation of Meldrum's Acid Derivatives and The Total Synthesis of Taiwaniaquinol B
(University of Waterloo, 2005)The intramolecular Friedel-Crafts acylation of aromatics with Meldrum?s acid derivatives catalyzed by metal trifluoromethanesulfonates and other Lewis acids is reported. Meldrum?s acids are easily prepared, functionalized, ... -
Catalytic Potential and Ligand Binding Properties of the Malachite Green RNA Aptamer
(University of Waterloo, 2008-09-18)The malachite green aptamer was originally engineered for binding specificity to malachite green (MG). The environment inside the aptamer’s electronegative binding pocket was previously harnessed to catalyze an ester ... -
Cation-Size-Dependent DNA Adsorption Kinetics and Packing Density on Gold Nanoparticles: An Opposite Trend
(American Chemical Society, 2014-11-11)The property of DNA is strongly influenced by counterions. Packing a dense layer of DNA onto a gold nanoparticle (AuNP) generates an interesting colloidal system with many novel physical properties such as a sharp melting ... -
Cellular Inclusion Bodies: Structure and Mechanisms
(University of Waterloo, 2022-08-18)Inclusion bodies (IBs) are insoluble aggregate structures that commonly form upon overexpression of proteins in heterologous hosts with relevance to biomedicine and biotechnology. These structures are of broad interest in ... -
Chalcogenides as thermoelectric materials
(Elsevier, 2019-02)Thermoelectric materials can be utilized to generate electricity from a temperature gradient, thereby recycling the nowadays abundant waste heat, as well as for cooling applications by creating a temperature gradient from ... -
Characterization of daptomycin oligomerization with perylene excimer fluorescence: Stoichiometric binding of phosphatidylglycerol triggers oligomer formation
(Elsevier, 2012-03)Daptomycin is a lipopeptide antibiotic that binds to and depolarizes bacterial cell membranes. Its antibacterial activity requires calcium and correlates with the content of phosphatidylglycerol in the target membrane. ... -
Characterization of glucose oxidation by gold nanoparticles using nanoceria
(Elsevier, 2014-04-30)Gold nanoparticles (AuNPs) can oxidize glucose, producing hydrogen peroxide and gluconic acid, which are the same products as those generated by glucose oxidase (GOx). In this regard, AuNPs are a nanozyme. Herein, a new ... -
Characterization of Hydrophobically Modified Starch Nanoparticles by Pyrene Fluorescence
(University of Waterloo, 2017-01-25)Starch nanoparticles (SNPs) were hydrophobically modified with propionic (C3) and hexanoic (C6) anhydride via esterification. Different degrees of substitution (DS) of the hydroxyl groups of the SNPs were achieved by varying ... -
Characterization of Langmuir-Blodgett Films by Electron Spin Resonance Spectroscopy
(University of Waterloo, 2020-01-15)Langmuir-Blodgett (LB) films built up with amphiphilic molecules have well-known optical, electrical and magnetic properties. For most applications, it is fundamentally important to understand the structure of the films. ...