Browsing Chemistry by Title
Now showing items 425-444 of 826
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Kinetics of Deliquescence of Ammonium Sulfate Particles
(University of Waterloo, 2008-05-15)The goal of this project was to study the deliquescence kinetics of aerosol particles of atmospheric significance. In the course of this work a novel experimental method was developed, which utilizes the measurement of the ... -
Label-Free Ag+ Detection by Enhancing DNA Sensitized Tb3+ Luminescence
(Multidisciplinary Digital Publishing Institute, 2016-08-26)In this work, the effect of Ag+ on DNA sensitized Tb3+ luminescence was studied initially using the Ag+-specific RNA-cleaving DNAzyme, Ag10c. While we expected to observe luminescence quenching by Ag+, a significant ... -
Lactate Detection Using Non-Enzymatic Catalytic Materials
(University of Waterloo, 2022-04-29)An Anastomotic leak (AL) can be defined as the leakage of gastrointestinal fluids into the abdominal cavity at the site of an anastomosis. It is a post-operative complication that affects thousands of patients annually ... -
Laser Desorption Solid Phase Microextraction
(University of Waterloo, 2006)The use of laser desorption as a sample introduction method for solid phase microextraction (SPME) has been investigated in this research project. Three different types of analytical instruments, mass spectrometry (MS), ... -
Ligand Specificity and Affinity in the Sulforhodamine B Binding RNA Aptamer
(Elsevier Inc., 2020-07-18)Binding affinity and selectivity are critical properties of aptamers that must be optimized for any application. The sulforhodamine B binding RNA aptamer (SRB‐2) is a somewhat promiscuous aptamer that can bind ligands ... -
LIGAND TRANSFER REACTIONS OF HYPERVALENT IODINE REAGENTS WITH PHOSPHORUS COMPOUNDS
(University of Waterloo, 2018-01-23)Many hypervalent iodine compounds are used as versatile reagents in synthetic organic chemistry. Hypervalent iodine reagents are capable of oxidizing trivalent phosphorus compounds into pentavalent, by transferring their ... -
Light-Activated Metal-Coordinated Supramolecular Complexes with Charge-Directed Self-Assembly
(American Chemical Society, 2013-02-21)Metal-coordinated materials are attractive for many applications including catalysis, sensing, and controlled release. Adenine and its derivatives have been widely used to generate many coordination complexes, polymers, ... -
Lipodepsipeptide Antibiotics: Total Synthesis and Mechanism of Action Studies Using 19F-NMR
(University of Waterloo, 2020-01-24)Daptomycin is a calcium-dependent cyclic lipodepsipeptide that is used clinically in the treatment of infections caused by pathogenic Gram-positive organisms, such as methicillin-resistant Staphylococcus aureus. Another ... -
The Lipopeptide Antibiotic Daptomycin: Its Interaction With Calcium And Membranes And The Effects Of Membrane Lipid Composition On Its Activity
(University of Waterloo, 2018-01-22)Daptomycin (Dap) is a calcium-dependent cyclic lipodepsipeptide antibiotic used clinically to treat infections with pathogenic Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). It targets ... -
Liposome Supported Metal Oxide Nanoparticles: Interaction Mechanism, Light Controlled Content Release and Intracellular Delivery
(Wiley, 2014-05-26)Zwitterionic phosphotydylcholine liposomes stably adsorb a number of metal oxide nanoparticles via its phosphate group. This is different from physisorption and fusion with SiO2. The hybrid materials can be internalized ... -
Liposome/Graphene Oxide Interaction Studied by Isothermal Titration Calorimetry
(American Chemical Society, 2015-03-15)The interaction between graphene oxide (GO) and lipid bilayers is important for fundamental surface science and many applications. In this work, isothermal titration calorimetry (ITC), cryo-TEM, and fluorescence spectroscopy ... -
Lithium ion conducting inorganic solid electrolytes and all solid-state lithium batteries
(University of Waterloo, 2021-11-08)As the world transitions away from fossil energy to green and renewable energy, electrochemical energy storage techniques, especially rechargeable batteries, increasingly become a vital component for this transition. High ... -
Long Range Polymer Chain Dynamics Probed with Pyrene Excimer Fluorescence
(University of Waterloo, 2016-09-27)A series of fluorescently labeled vinyl polymers bearing a C1-C18 side-chain (namely poly(methyl methacrylate), poly(butyl methacrylate), poly(octyl methacrylate), poly(lauryl methacrylate), and poly(stearyl methacrylate) ... -
Long Range Polymer Chain Dynamics Studied by Fluorescence Quenching
(American Chemical Society, 2016-09-13)Over the years, fluorescence quenching experiments have provided a robust analytical means to retrieve information about the internal dynamics of macromolecules in general and the long range polymer chain dynamics (LRPCD) ... -
Long-Range, Polymer Chain Dynamics of a "Stiff" Polymer. Fluorescence from Poly(isobutylene-alt-maleic anhydride) with N-(1-Pyrenylmethyl)succinimide Groups
(American Chemical Society, 2017-04-25)The steady-state fluorescence (SSF) spectra and time resolved fluorescence (TRF) decays of five poly(isobutylene-alt-maleic anhydride) copolymers (PIMA), randomly labeled with N-(1-pyrenyl methyl)succinimide groups (Py-PIMA), ... -
Low Temperature Insights into the Crystal and Magnetic Structure of a Neutral Radical Ferromagnet
(Royal Society of Chemistry, 2021-09-16)The crystal structure of the radical ferromagnet 1a at 2 K reveals a contraction in the unit cell c constant which, at the molecular level, translates into a decrease in slippage of the radical π-stacks and an increase in ... -
Machine Learning Model for Repurposing Drugs to Target Viral Diseases
(University of Waterloo, 2023-01-26)With recent events, such as the Covid-19 pandemic, it is increasingly important to develop strategies to combat viral diseases. Due to technological advancements, computer-aided drug design and machine learning (ML)-based ... -
Magnesium Silicide Based Thermoelectric Nanocomposites
(University of Waterloo, 2016-01-15)The major objective of this thesis was to investigate how far the thermoelectric (TE) properties of magnesium silicide based materials can be enhanced via doping, alloying, and nanostructuring. The investigation of Sb and ... -
Magnetic and Structural Investigation of Manganese Doped SnO_2 and In_2 O_3 Nanocrystals
(University of Waterloo, 2013-09-11)Diluted magnetic semiconductor oxides (DMSOs) have received great attention recently due to their outstanding applications in optoelectronic and spintronic devices. Ever since the initial observation of ferromagnetism at ... -
Magnetic Iron Oxide Nanoparticle Seeded Growth of Nucleotide Coordinated Polymers
(American Chemical Society, 2016-06-22)The introduction of functional molecules to the surface of magnetic iron oxide nanoparticles (NPs) is of critical importance. Most previously reported methods were focused on surface ligand attachment either by physisorption ...