Browsing Science (Faculty of) by Title
Now showing items 2358-2377 of 3018
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Robust thermal control for CMOS-based lab-on-chip systems
(Institute of Physics, 2015-07-01)The need for precise temperature control at small scales has provided a formidable challenge to the lab-on-chip community. It requires, at once, good thermal conductivity for high speed operation, good thermal isolation ... -
Robust Time-Optimal Control for the One-Dimensional Optical Lattice for Quantum Computation
(University of Waterloo, 2011-10-04)Quantum information is a growing field showing exciting possibilities for computational speed-up and communications. For the successful implementation of quantum computers, high-precision control is required to reach ... -
A Rock Borehole Packer System for Identifying Hydraulically Active Fractures Under Natural Gradient Flow
(University of Waterloo, 2008-05-27)To improve capabilities for understanding and predicting contaminant migration in fractured rock there is need for better field methods to identify the fractures that have active groundwater flow. Current methods have ... -
The role of ACC deaminase in plant growth promotion by the endophytic bacterium Burkholderia phytofirmans PsJN
(University of Waterloo, 2008-08-01)The endophytic bacterium Burkholderia phytofirmans PsJN has been previously shown to promote plant growth. This bacterium produces siderophores, indoleacetic acid (IAA) and the enzyme 1-aminocyclopropane-1-carboxylate (ACC) ... -
The Role of Carbonic Anhydrase in Promoting CO2 Capture and Operation of Bicarbonate-Fed Electrolyzers
(University of Waterloo, 2022-08-23)Capturing CO2 through chemical absorption offers a sustainable solution to mitigate rising CO2 emissions which are widely agreed to be the primary contributor to climate change. Among various capture solutions, bicarbonate ... -
The Role of Domain II and Domain IV Extracellular Turrets in Determining Ion Selectivity in the T-type Calcium Channel from Lymnaea stagnalis
(University of Waterloo, 2016-07-20)The T-type calcium channel from the pond snail Lymnaea stagnalis, LCav3, undergoes alternative splicing in exon 12. Exon 12 codes for the L5 structure (S5-P) in Domain II (DII), which is dubbed the "turret". The turret is ... -
The Role of Glucocorticoid Receptor Signaling in Zebrafish Development
(University of Waterloo, 2013-01-28)These studies present a series of novel roles for glucocorticoid signaling in the developing zebrafish embryo. The best-characterized roles of cortisol, the primary circulating corticosteroid in teleost fish, are known to ... -
The role of hindsight in the transient stem cell niche of the Drosophila melanogaster larval midgut
(University of Waterloo, 2018-04-30)The composition of the larval Drosophila midgut includes cells known as adult midgut precursors (AMPs) that represent the founder cells for the adult midgut. During the first and second larval instar stages, AMPs are ... -
The role of hindsight in transcriptional regulation during Drosophila melanogaster development
(University of Waterloo, 2014-09-16)In Drosophila melanogaster, hindsight (hnt) encodes a putative Zinc-finger transcription factor that is expressed in a highly complex pattern during development. Despite an apparent wealth of information regarding the ... -
The Role of Melatonin in Amyloid Interactions with the Model Neuronal Membranes
(University of Waterloo, 2023-11-29)The amyloid cascade hypothesis has long directed research efforts in understanding the pathogenesis of Alzheimer’s disease (AD), ever since it was first proposed through clinical evidence by Hardy and Higgins in 1992. ... -
The Role of MMPs, Smad3 and Heat Shock Proteins in TGF-β-Induced Anterior Subcapsular Cataract Development
(University of Waterloo, 2007-06-18)Transforming growth factor beta (TGF-β) has been implicated in anterior subcapsular cataract (ASC) development. In the first section of this thesis, an in-vitro rat lens model was used to determine the role of matrix ... -
The Role of Nitrate in Controlling Iron Release from Sediment during Anoxia in Dimictic, Fresh Water Lakes
(University of Waterloo, 2018-01-16)Recent research suggests the availability of reduced iron (Fe) is key in allowing cyanobacteria to outcompete eukaryotic phytoplankton. Cyanobacteria have a greater need for Fe than their eukaryotic competition and are ... -
Role of NOS-like proteins found in bacteria
(University of Waterloo, 2007-01-22)Nitric oxide (•NO) is a molecule with diverse biological effects involved in both signaling and defense mechanisms in mammalian systems. The production of •NO is catalyzed from L-Arginine by a family of enzymes known as ... -
Role of PINCH during early Xenopus embryogenesis
(University of Waterloo, 2012-08-31)In the Xenopus embryo, cell rearrangements during early development require the dynamic modulation of adhesion. Cells primarily use the integrin family of transmembrane receptors for attachment to and interpretation of the ... -
Role of Prolyl 4-Hydroxylase in Pancreatic ß-cell Insulin Secretion
(University of Waterloo, 2017-08-30)Type 2 diabetes mellitus (T2D) is characterized by chronic hyperglycemia and peripheral insulin resistance. In response to elevated blood glucose levels, pancreatic β-cells release insulin which occurs in a biphasic ... -
The role of social preferences in the organization of a gregarious mammal colony
(University of Waterloo, 2022-12-02)Social preferences are often demonstrated to exist in “intelligent”, long-lived species, such as cetaceans and primates, where individuals have the opportunity to form relationships with conspecifics through repeated ... -
The role of sodium and calcium permeable T-type channels in generating pacemaking currents in invertebrates
(University of Waterloo, 2016-09-27)T-type calcium channels (Cav3) play a key role in generating rhythmic action potentials in excitable cells such as the heart pacemaker and sleep-wake cycles in the thalamus. T-type channels are low voltage-activated ... -
The role of submersed macrophytes in river eutrophication and biogeochemical nutrient cycling
(University of Waterloo, 2012-09-28)The goal of this work is to contribute to the understanding eutrophication in large rivers with a detailed study of the Grand River, an impacted river in highly agricultural and urbanized Southern Ontario. It focuses on ... -
Role of Symmetry in Hisactophilin Folding
(University of Waterloo, 2009-02-23)Hisactophilin is a histidine-rich actin binding protein from Dictyostelium discoideum; it is a member of the β-trefoil superfamily and exhibits a characteristic tertiary structure with three-fold symmetry. The effect of ... -
The Role of the Group Environment in Galaxy Evolution
(University of Waterloo, 2010-08-11)The majority of typically sized galaxies in the local Universe reside in a common dark matter halo with other similar galaxies known as a galaxy group. However, this was not always the case. Nine billion years ago, when ...