Browsing Science (Faculty of) by Title
Now showing items 2378-2397 of 3025
-
Role of Prolyl 4-Hydroxylase in Pancreatic ß-cell Insulin Secretion
(University of Waterloo, 2017-08-30)Type 2 diabetes mellitus (T2D) is characterized by chronic hyperglycemia and peripheral insulin resistance. In response to elevated blood glucose levels, pancreatic β-cells release insulin which occurs in a biphasic ... -
The role of social preferences in the organization of a gregarious mammal colony
(University of Waterloo, 2022-12-02)Social preferences are often demonstrated to exist in “intelligent”, long-lived species, such as cetaceans and primates, where individuals have the opportunity to form relationships with conspecifics through repeated ... -
The role of sodium and calcium permeable T-type channels in generating pacemaking currents in invertebrates
(University of Waterloo, 2016-09-27)T-type calcium channels (Cav3) play a key role in generating rhythmic action potentials in excitable cells such as the heart pacemaker and sleep-wake cycles in the thalamus. T-type channels are low voltage-activated ... -
The role of submersed macrophytes in river eutrophication and biogeochemical nutrient cycling
(University of Waterloo, 2012-09-28)The goal of this work is to contribute to the understanding eutrophication in large rivers with a detailed study of the Grand River, an impacted river in highly agricultural and urbanized Southern Ontario. It focuses on ... -
Role of Symmetry in Hisactophilin Folding
(University of Waterloo, 2009-02-23)Hisactophilin is a histidine-rich actin binding protein from Dictyostelium discoideum; it is a member of the β-trefoil superfamily and exhibits a characteristic tertiary structure with three-fold symmetry. The effect of ... -
The Role of the Group Environment in Galaxy Evolution
(University of Waterloo, 2010-08-11)The majority of typically sized galaxies in the local Universe reside in a common dark matter halo with other similar galaxies known as a galaxy group. However, this was not always the case. Nine billion years ago, when ... -
The Role of Transverse Faults in Late Gold Mineralization: A Structural Study of the Maskinonge Lake Fault, Michipicoten Greenstone Belt, Ontario
(University of Waterloo, 2023-10-25)The Maskinonge Lake fault is a late NW-striking fault that occurs at a high angle to the structural features of the gold-producing Goudreau Lake Deformation Zone (GLDZ) in the Michipicoten greenstone belt. The fault is ... -
The Role of Wastewater Testing for SARS-CoV-2 Surveillance
(Ontario COVID-19 Science Advisory Table, 2021-08-26)Wastewater testing for SARS-CoV-2 is relatively new; however, it builds on existing public health surveillance infrastructure. There is a limited but growing evidence base for its use, despite notable interpretation ... -
The Role of Wetland Pond Permanence in the Assembly of Biological Communities in the Prairie Potholes of Alberta
(University of Waterloo, 2020-05-06)Wetlands in the Prairie Pothole Region (PPR) support numerous biological communities, and the composition of these communities depends on the length of time ponded water is present (i.e., hydroperiod or permanence class). ... -
The Roles of Causal Propagator in Relativistic Quantum Information
(University of Waterloo, 2023-05-29)This thesis focuses on the roles of causal propagator — the expectation value of the field commutator — in relativistic quantum information. Consider two observers Alice and Bob, each carrying a two-level quantum system ... -
The Roles of Conserved Dbf4 Motifs in DNA Replication and Checkpoint Responses in Saccharomyces cerevisiae
(University of Waterloo, 2010-01-18)The Dbf4 protein is involved in the initiation of DNA replication, in complex with Cdc7 kinase, and also plays a role in the intra-S-phase checkpoint response via an interaction with Rad53 in Saccharomyces cerevisiae. The ... -
Roost Selection and Mass Variation Patterns of Temperate Bats in Eastern Canada
(University of Waterloo, 2021-08-23)Animals are expected to adjust their resource selection and behavioural patterns to improve fitness outcomes, such as fecundity or offspring survival. For long-lived hibernators, decisions made in each annual cycle may ... -
The S-Matrix of Gauge and Gravity Theories and The Two-Black Hole Problem
(University of Waterloo, 2020-10-01)This thesis is devoted to diverse aspects of scattering amplitudes in gauge theory and gravity including interactions with matter particles. In Part I we focus on the applications of massive scattering amplitudes in gravity ... -
The Saliva Exposome for Monitoring of Individuals’ Health Trajectories
(Environmental Health Perspectives - United States Federal Government, 2017-07-20)Background: There is increasing evidence that environmental, rather than genetic, factors are the major causes of most chronic diseases. By measuring entire classes of chemicals in archived biospecimens, exposome-wide ... -
Salt Mass Balance Study and Plant Physiological Responses for an Enhanced Salt Phytoremediation System
(University of Waterloo, 2011-07-11)Salinity is one of the most severe environmental factors that limits global crop yield. Enhanced phytoremediation using plant growth promoting rhizobacteria (PGPR) has proven to be an effective and environmentally responsible ... -
Satellite Dynamics in Dark Matter Halos
(University of Waterloo, 2010-09-01)I have used an analytic model of tidal interactions to predict the evolution of a substructure in a static dark matter halo. Given the initial conditions of the satellite and background halo, the model predicts with high ... -
Scanning Tunneling Microscopy of Electrically Driven Phase Transitions in a Charge Density Wave Material
(University of Waterloo, 2022-03-25)The 1T polytype of the van der Waals material TaS2, has been studied extensively as a strongly correlated system. Exhibiting several different charge density wave (CDW) states, the phase diagram of 1T-TaS2 has been explored ... -
Scattering Equations and S-Matrices
(University of Waterloo, 2015-06-25)We introduce a new formulation for the tree-level S-matrix in theories of massless particles. Sitting at the core of this formulation are the scattering equations, which yield a map from the kinematics of a scattering ... -
A Scoping Review of Frailty and Acute Care in Middle-Aged and Older Individuals with Recommendations for Future Research
(Canadian Geriatrics Society, 2017-03-31)There is general agreement that frailty is a state of heightened vulnerability to stressors arising from impairments in multiple systems leading to declines in homeostatic reserve and resiliency, but unresolved issues ... -
A Search for Nearby Dwarf Galaxies
(University of Waterloo, 2014-09-25)Dwarf galaxies can be used to trace invisible dark matter substructure. Studies of the properties of dwarf galaxy populations are crucial in solving the so-called ``Missing Satellite Problem'', and hold important implications ...