Browsing Chemistry by Title
Now showing items 585-604 of 839
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Polysaccharides for Bitumen Extraction, Environmental Decontamination and Cell Culture
(University of Waterloo, 2022-02-07)Polysaccharides are polymeric carbohydrates with long chains of monosaccharide units linked by glycosidic bonds. Some of the most prevalent polysaccharides in nature include starch and chitin. For the work reported in this ... -
Porous chitosan microspheres as microcarriers for 3D cell culture
(Elsevier, 2018-12-15)Highly porous chitosan microspheres (CSM) were prepared through emulsion-based thermally induced phase separation (TIPS) without using toxic crosslinkers and chemical porogenic agents other than ice. The CSM had an average ... -
Predicting and Measuring Molecular Mechanisms of Protein Aggregation
(University of Waterloo, 2011-08-30)Protein aggregation is a hallmark of a number of neurodegenerative disorders including Alzheimer’s Disease, Huntington’s Disease, and Amyotrophic Lateral Sclerosis. Despite the common occurrence of protein aggregation in ... -
Preparation and Characterization of Temperature-Responsive Polymeric Surfactants
(University of Waterloo, 2014-01-28)Canada has large reserves of heavy oil stored in the form of oil sands in the Athabasca region. This type of heavy oil does not flow at room temperature and its agglomeration with sand complicates its extraction. Consequently, ... -
Preparation of a Multi-Part Varkud Satellite Ribozyme Variant for Kinetics Studies
(University of Waterloo, 2009-09-22)The Varkud Satellite (VS) ribozyme is the largest of the “small” nucleolytic ribozymes and is the only one for which there are no high resolution crystal structures available. The VS ribozyme comprises a catalytic domain ... -
Preparation of Ruthenium and Iridium Pincer-Type Pyridylidenes
(University of Waterloo, 2009-08-31)A new POCOP pincer-type ligand was synthesized and characterized. This new ligand gave rise to the first POCOP pyridylidene pincer-type ruthenium and iridium complexes. Investigations into structural and electronic parameters ... -
Preparing and Tuning the Reactivity of Palladium Carbenes and an Unusual Catalytic Isomerization of Diphenylcyclopropanes
(University of Waterloo, 2007-09-26)The preparation of palladium carbene intermediates from diphenylketene is proposed. Experiments to trap these intermediates with alkenes have been conducted and optimized, with cyclopropanes being prepared in up to 69% ... -
Preparing Nanotubes via Polymerization of Diacetylene Functionality Containing Carbon-based Macrocycles
(University of Waterloo, 2013-09-05)Nanofibers and nanotubes have been extensively studied in materials science due to their extraordinary thermal conductivity, excellent mechanical and electrical properties, and their potential capability for gas storage. ... -
Probing Long-Range Polymer Chain Dynamics of Poly(L-lysine) in Aqueous Solution by Fluorescence
(University of Waterloo, 2011-02-24)Information about long-range polymer chain dynamics (LRPCD) can be obtained by attaching a luminophore and its quencher onto a polymer and monitoring the rate at which the luminophore is quenched. Since a quenching event ... -
Probing Side Chain Dynamics of Branched Macromolecules by Pyrene Excimer Fluorescence
(American Chemical Society, 2016-01-12)Four different pyrene-labeled polymers were prepared by radical copolymerization of n-butyl methacrylate (BMA) and 1-pyrenemethyl methacrylate (PyEG(0)-MA), 1-pyrenemethoxyethyl methacrylate (PyEG(1)-MA), 1-pyrene-methox ... -
Probing the Electronic and Magnetic Properties of Transparent Semiconductor Nanowires using X-ray Absorption Spectroscopic Methods
(University of Waterloo, 2015-12-16)Control of electron spins in individual magnetically doped semiconductor nanostructures has considerable potential for quantum information processing and storage. The manipulations of dilute magnetic interactions have ... -
Probing the Interactions between Mimics of Pour Point Depressants (PPDs) and Viscosity Index Improvers (VIIs) in Engine Oil Using Fluorescently Labeled PPDs
(American Chemical Society, 2019-03-18)The level of interpolymeric interactions experienced by a pyrene-labeled poly(octadecyl methacrylate) labeled with 6.7 mol% of 1-pyrenebutanol (Py(6.7)-PC18MA) was characterized by fluorescence in the presence of an amorphous ... -
Production of a camelid antibody in CHO cells and its potential for the in vitro modification of its N-glycan using N- acetylglucosaminyltransferase III produced in insect cells
(University of Waterloo, 2015-01-07)Monoclonal antibodies have been extensively used for clinical diagnosis over the years. Beyond their ability to bind antigens, their ability to invoke or evade immune responses has also led to their use in therapeutic ... -
Profiling Metal Oxides with Lipids: Magnetic Liposomal Nanoparticles Displaying DNA and Proteins
(Wiley, 2016-09-19)Metal oxides include many important materials with various surface properties. For biomedical and analytical applications, it is desirable to engineer their biocompatible interfaces. Herein, a phosphocholine liposome (DOPC) ... -
Programmable Assembly of DNA-Functionalized Liposomes by DNA
(American Chemical Society, 2011-02-22)Bionanotechnology involves the use of biomolecules to control both the structure and property of nanomaterials. One of the most studied examples is DNA-directed assembly of inorganic nanoparticles such as gold nanoparticles ... -
Properties of Hydrogels Incorporating Graphene Oxide-based Nanoparticles for Tissue Engineering Purposes
(University of Waterloo, 2016-01-21)Tissue engineering involves designing and fabricating scaffolds for tissue regeneration and replacement. Much research has focused on identifying the key factors that affect scaffold performance and the necessary material ... -
Protection and Promotion of UV Radiation-Induced Liposome Leakage via DNA-Directed Assembly with Gold Nanoparticles
(Wiley, 2011-07-26)DNA-functionalized gold nanoparticles and liposomes are assembled by a linker DNA. The gold nanoparticles can either protect the liposome from UV radiation induced leakage or can promote the leakage, depending on the DNA ... -
Protein Engineering of Bacterioferritin: Applications to Bionanotechnology
(University of Waterloo, 2014-09-24)Biological protein assemblies are the products of evolutionary necessity that have arisen to protect the cell, improve reaction rates, and/or compartmentalize biological systems. Belonging to this category of sel-assembling ... -
Protein Engineering of Microbial Ferritins
(University of Waterloo, 2019-09-23)Nanotechnology has become a field of intense interest due to its applications in medicine, cosmetics, energy, and fabrics. The field has evolved to include nanodimensional self-assembling cage proteins which are multisubunit ... -
Pyrene Excimer Fluorescence as a Direct and Easy Experimental Means to Characterize the Length Scale and Dynamics of Polypeptide
(American Chemical Society, 2018-04-26)This report provides evidence that the blobs characterized through the application of the fluorescence blob model (FBM) to the analysis of the fluorescence decays acquired with pyrene-labeled polypeptides are equivalent ...