Browsing Science (Faculty of) by Title
Now showing items 2205-2224 of 3018
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Proteomics Analysis of Protein-Producing Chinese Hamster Ovary Cells during Apoptosis in Prolonged Cultivation
(University of Waterloo, 2010-05-21)Among the factors important for maintaining productivity of recombinant proteins in mammalian cells, culture lifetime, cell density and cell viability are three simple but essential aspects that can greatly influence the ... -
Proterozoic zircon dates from auriferous zones at the Island Gold deposit: implications for late gold remobilization in the Superior Province
(University of Waterloo, 2024-02-13)The Island Gold deposit is a high-grade Archean orogenic gold deposit within the Michipicoten greenstone belt of the Superior Province. Hosted within the ~2750 Ma felsic to intermediate Wawa metavolcanic assemblage, gold ... -
Protocol development for reliable isolation of tear-film neutrophils and in vitro functionality testing
(University of Waterloo, 2019-09-19)During prolonged eye closure, such as during sleep, leukocytes are recruited to the ocular surface, with polymorphonuclear neutrophils (PMNs) representing the largest population. PMNs are essential inflammatory cells ... -
The Proximon: Representation, Evaluation, and Applications of Metagenomic Functional Interactions
(University of Waterloo, 2017-09-19)The effective use of metagenomic functional interactions represents a key prospect for a variety of applications in the field of functional metagenomics. By definition, metagenomic operons represent such interactions but ... -
Psychophysical and Clinical Investigations of Ocular Discomfort
(University of Waterloo, 2012-09-26)Purpose To investigate ocular surface sensations, specifically ocular discomfort using psychophysical and clinical techniques. The measurement of discomfort on the ocular surface has been limited to the use of traditional ... -
Psychophysical Studies Of Motion Perception In Autism Spectrum Disorders
(University of Waterloo, 2019-05-23)Introduction Studies have shown considerable evidence of visual dysfunction in Autism Spectrum Disorders (ASD). Motion perception research in ASD reports a superior performance in processing motion information of fine ... -
Pulse Flow Enhancement in Two-Phase Media
(University of Waterloo, 2001)This laboratory project has been done to evaluate pressure pulsing as an Enhanced Oil Recovery (EOR) technique. To perform the study, a consistent laboratory methodology was developed, including the construction of a ... -
Pulsed Biosparging of the E10 Gasoline Source in the Borden Aquifer
(University of Waterloo, 2008-10-27)Air sparging is a technique used to remediate gasoline contamination. In sparging, air is injected below the target zone and removes contamination via two separate mechanisms; volatilization and biodegradation. In ... -
Purification and Characterization of O2-insensitive Pyruvate Decarboxylase from Sulfolobus species
(University of Waterloo, 2020-06-17)Pyruvate decarboxylase (PDC) is a key enzyme in a two-step pathway for the production of ethanol. It catalyzes the non-oxidative decarboxylation of pyruvate to acetaldehyde in many mesophilic organisms. No conventional PDC ... -
Purification and determination of oxidative modifications of the thermostable alcohol dehydrogenase from Thermococcus guaymasensis
(University of Waterloo, 2019-09-13)Hyperthermophiles are microorganisms that grow optimally at 80°C and above. They have been found to be resilient to extremes of pH, redox potential, pressure and salinity. Moreover, they can utilize a wide range of ... -
A Purity Benchmarking Study of Superconducting Single-qubit Fluctuations
(University of Waterloo, 2023-07-31)Quantum processes are susceptible to errors. Over the years, numerous noise models, such as two-level system noise and flux noise, have been proposed by physicists to describe the mechanisms behind the error sources ... -
Pyrene Excimer Fluorescence as a Direct and Easy Experimental Means to Characterize the Length Scale and Dynamics of Polypeptide
(American Chemical Society, 2018-04-26)This report provides evidence that the blobs characterized through the application of the fluorescence blob model (FBM) to the analysis of the fluorescence decays acquired with pyrene-labeled polypeptides are equivalent ... -
Pyrene Excimer Formation: A Tool to Study Macromolecular Conformations in Solution
(University of Waterloo, 2024-04-26)The current view for fluorescence collisional quenching (FCQ) experiments is that no quantitative information can be retrieved from macromolecules containing more than a single dye-quencher pair attached at two specific ... -
Pyrenyl Derivative with a Four-Atom Linker That Can Probe the Local Polarity of Pyrene-Labeled Macromolecules
(American Chemical Society, 2016-02-04)The fluorescent probe 1-pyrenemethoxyethanol (PyMeEGOH) was designed to replace commercially available 1-pyrenebutanol (PyButOH) as an alternative fluorescent label to probe the internal dynamics and interior polarity of ... -
A Quality Assurance Evaluation of Hydromorphone Adverse Events Post-Implementation of a Safety Initiative
(University of Waterloo, 2019-08)Purpose: Hydromorphone is a potent opioid that may lead to respiratory and central nervous system depression prompting naloxone use. The primary objective of this study was to evaluate whether a safety initiative implemented ... -
Quantification and Profiling of Hepatic Retinoids in Freshwater Fishes by Liquid Chromatography – Tandem Mass Spectrometry
(University of Waterloo, 2018-03-26)Retinoids (vitamin A1) are a class of compounds essential for a number of physiological processes including vision and immune system function. They are stored as biologically inactive retinyl esters which are mobilized ... -
Quantification of MUCIN 1, cell surface associated and MUCIN16, cell surface associated proteins in tears and conjunctival epithelial cells collected from postmenopausal women
(Molecular Vision, 2013-05-04)Purpose: To quantify the expression of mucin 1, cell surface associated (MUC1) and mucin 16, cell surface associated (MUC16) proteins and messenger ribonucleic acid (mRNA) in a cohort of postmenopausal women (PMW), to ... -
Quantification of Oxygen Dynamics in the Grand River Using a Stable Isotope Approach
(University of Waterloo, 2010-04-30)The current study monitored DO, stable isotopes of O2 (δ18O-O2 and δ18O-H2O) along with water quality parameters on both a diel and day-time only basis in the Grand River over several seasons and locations. A dynamic dual ... -
Quantification of the Long-Term Effects from Nutrient Reductions on Groundwater Nitrate Concentrations in an Agricultural Setting
(University of Waterloo, 2008-06-06)The Ontario Nutrient Management Act (2002) recommends agricultural Beneficial Management Practices (BMPs) that involve reductions in nutrient applications of nitrogen (N) to fields to improve underlying groundwater quality, ... -
Quantifying entanglement of rotor chains using basis truncation: Application to dipolar endofullerene peapods
(American Institute of Physics, 2018-02-21)We propose a variational approach for the calculation of the quantum entanglement entropy of assemblies of rotating dipolar molecules. A basis truncation scheme based on the total angular momentum quantum number is proposed. ...