Browsing Science (Faculty of) by Title
Now showing items 2046-2065 of 3022
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Peptide and peptide-carbon nanotube hydrogels as scaffolds for tissue & 3D tumor engineering
(Elsevier, 2018-03-15)The use of hybrid self-assembling peptide (EFK8)-carbon nanotube (SWNT) hydrogels for tissue engineering and in vitro 3D cancer spheroid formation is reported. These hybrid hydrogels are shown to enhance the attachment, ... -
Peptide and peptide-carbon nanotube hydrogels as scaffolds for tissue & 3D tumor engineering
(Elsevier, 2018-03-15)The use of hybrid self-assembling peptide (EFK8)-carbon nanotube (SWNT) hydrogels for tissue engineering and in vitro 3D cancer spheroid formation is reported. These hybrid hydrogels are shown to enhance the attachment, ... -
Peptide-Driven Tri-Modal Gene Delivery Systems (PDTMG): Novel Versatile Peptide-Based Lipopolyplexes Incorporating Peptide-Functionalized Gemini Surfactants for Targeted Gene Therapy- Implementation of RGD Motifs as a Means for Endosomal Escape
(University of Waterloo, 2018-09-04)The development of non-viral gene delivery vectors is highly challenging and aims to provide a safe while cost-effective manufacturing alternative to viral vectors. Eleven novel gemini surfactants (G4-G14) were designed ... -
Perceptions of Community-Dwelling Patients on the Impact of the Discontinuation of OxyContin® on their Pain Management: A Mixed Methods Study
(University of Waterloo, 2014-09-02)Chronic pain is considered a major health problem in older adults. OxyContin®, one of the most commonly used medications for treating pain in Canada, was recently discontinued, and delisted from the Ontario Drug Formulary ... -
Performance of Treatment Media for the Stabilization of Mercury under Variable Geochemical Conditions
(University of Waterloo, 2010-10-01)Mercury-contaminated sediments are found in many locations throughout North America and the world. Release of Hg from such sediments and subsequent biological uptake can result in biomagnification in associated ecosystems. ... -
Periodically-driven quantum many-body systems, many-body localization and machine learning
(University of Waterloo, 2018-03-09)Despite the exponentially large amount of information required in the quantum description of many-body systems, finite size numerical simulations have paved the way for recent progress in the understanding of quantum phases ... -
Persistence of Artificial Sweeteners, Phosphorus and Nitrogen in Three Septic System Plumes with Differing Redox Conditions
(University of Waterloo, 2018-10-31)Septic systems are widely used for on-site wastewater treatment throughout Canada, including at most of Ontario’s provincial parks. They are frequently located in unconfined aquifer systems that may also be used for water ... -
Perspectives from Pharmacists, Prescribers and Patients on Sharing Medication Reason for Use
(University of Waterloo, 2020-05-05)Pharmacists rarely receive the reason a medication was prescribed, often referred to as reason for use (RFU). Pharmacists can use this information to better counsel patients, support patients in taking medications safely, ... -
Perspectives on the Formalism of Quantum Theory
(University of Waterloo, 2012-09-26)Quantum theory has the distinction among physical theories of currently underpinning most of modern physics, while remaining essentially mysterious, with no general agreement about the nature of its principles or the ... -
Perturbations to nutrient and carbon cycles by river damming
(University of Waterloo, 2017-06-30)The damming of rivers represents one of the most far-reaching human modifications to the flows of water and associated matter from land to sea. Globally there are over 70 000 large dams whose reservoirs store more than ... -
Petabase-scale Data Mining Identifies Novel Clostridial Species and Neurotoxins Associated with Ancient Human DNA
(University of Waterloo, 2022-09-08)Analyzing microbial genomes found in archaeological samples can provide insights into the origins of modern infectious diseases. A large-scale metagenomic analysis of archeological samples discovered bacterial species ... -
Petrogenesis of Archean granitoids: Insights from inverse and forward modelling
(University of Waterloo, 2022-06-24)Archean granitoids are the earliest representation of continental crust on Earth. The Archean geological record is dominated by rocks of the tonalite–trondhjemite–granodiorite (TTG) suite, which are thought to have formed ... -
The Petrogenesis of Pseudocarbonatites in Bancroft Region, Southwestern Grenville Province
(University of Waterloo, 2022-02-15)Carbonatites are rare igneous rocks that form from fractionation of carbonate-rich, silica undersaturated magma. The petrogenesis of pseudocarbonatites (rocks that are similar to carbonatites, but without a clear mantle ... -
Petrogenesis of the Bissett Creek flake graphite deposit: Implications for regional graphite mineralization models in the Grenville Province, Ontario
(University of Waterloo, 2018-07-16)Graphite is a critical component of green and renewable energy technologies. In Ontario, graphite deposits are scattered throughout the pre-Grenvillian Laurentian Margin and the Composite Arc Belt of the Grenville Province. ... -
Petroleomic analysis of the treatment of naphthenic organics in oil sands process-affected water with buoyant photocatalysts
(Elsevier, 2018-09-15)The persistence of toxicity associated with the soluble naphthenic organic compounds (NOCs) of oil sands process-affected water (OSPW) implies that a treatment solution may be necessary to enable safe return of this water ... -
PETROLOGY, TECTONIC SETTING, AND REGIONAL IMPLICATIONS OF THE OPHIOLITIC LIUYUAN COMPLEX, NW CHINA
(University of Waterloo, 2023-01-03)Located along the southern margin of the Central Asian Orogenic Belt (CAOB), the mafic 290-280 Ma Liuyuan Complex stratigraphy and tectonic setting have been controversial for decades. Here, the results of a detailed field ... -
pH-Responsive Poly(Ethylene Glycol)- block -Polylactide Micelles for Tumor-Targeted Drug Delivery
(American Chemical Society, 2017-08-16)A biodegradable micellar drug delivery system with a pH-responsive sheddable PEG shell was developed using an acetal-linked poly(ethylene glycol)-block-polylactide (PEG-a-PLA) copolymer and applied to the tumoral release ... -
Pharmaceutical Applications of Gemini Surfactants
(University of Waterloo, 2011-01-10)Gemini surfactants are an intriguing class of surface active agents that are comprised of two surfactant monomers chemically linked at or near the headgroups by a rigid or flexible spacer. In comparison to their corresponding ... -
Pharmacist experience with providing care for patients with chronic pain in the community setting: A qualitative study
(University of Waterloo, 2017-01-20)Objectives: Chronic pain is a condition pharmacists frequently encounter in practice; however, the pharmacist’s role in the management of chronic pain is under-investigated. This study examines pharmacist perceptions and ... -
Pharmacokinetic and economic implications when switching between hemophilia A treatments
(University of Waterloo, 2023-04-18)Hemophilia is a bleeding disorder in which the blood is unable to form clots, and is also classified as severe (defined as having an endogenous factor VIII [FVIII] concentration < 1 IU/dL, or 1%), moderate (1-5%) or mild ...