Browsing Theses by Subject "Biology"
Now showing items 1-20 of 305
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1-AMINOCYCLOPROPANE-1-CARBOXYLATE (ACC) DEAMINASE GENES IN RHIZOBIA: ISOLATION AND CHARACTERIZATION
(University of Waterloo, 2007-05-14)A collection of 233 putative Rhizobia strains from 30 different sites across Saskatchewan, Canada was assayed for ACC deaminase activity, with 27 of the strains displaying activity. When all 27 strains were characterized ... -
Alternative splicing of Lymnaea Cav3 and NALCN ion channel genes serves to alter biophysical properties, membrane expression, and ion selectivity
(University of Waterloo, 2012-08-30)Evidence is presented that Lymnaea contains homologues for mammalian Cav3 and NALCN 4-domain ion channels, which retain key amino acid sequence motifs that differentiate these channels from other 4-domain types. Molecular ... -
Analysis of heat shock protein 30 gene expression and function in Xenopus laevis A6 kidney epithelial cells
(University of Waterloo, 2014-04-30)Heat shock proteins (HSPs) are molecular chaperones that assist in protein synthesis, folding and degradation and prevent stress-induced protein aggregation. The present study examined the pattern of accumulation of HSP30 ... -
Analysis of heat shock-, sodium arsenite- and proteasome inhibitor-induced heat shock protein gene expression in Xenopus laevis
(University of Waterloo, 2009-05-01)Previous studies have focused on the effect of individual stressors on hsp gene expression in eukaryotic organisms. In the present study, I examined the effect of concurrent low doses of sodium arsenite and mild heat shock ... -
Analysis of premature loss of the extraembryonic Amnioserosa in Drosophila morphogenetic mutants
(University of Waterloo, 2009-01-23)During Drosophila embryogenesis, an extra-embryonic tissue, known as the amnioserosa (AS), is required for the morphogenetic processes of germ band retraction (GBR) and dorsal closure (DC). Being extra-embryonic, the AS ... -
Analysis of Programmed Cell Death in the Amnioserosa, an Extra-embryonic Epithelium in Drosophila melanogaster
(University of Waterloo, 2008-01-24)The amnioserosa (AS) is an epithelium that plays major roles in two crucial morphogenetic processes during Drosophila embryogenesis: Germ Band Retraction (GBR) and Dorsal Closure (DC). The AS is extraembryonic and as such, ... -
Analysis of the structural determinants for voltage-dependent G protein modulation of synaptic Cav2 channels
(University of Waterloo, 2008-08-28)Specialized voltage-gated calcium channels in the Cav2 channel class (such as Cav2.2, N-type) mediate neurotransmitter release from presynaptic nerve terminals. Cav2.2 channels are exquisitely sensitive to inhibition by ... -
Application of Different Measures of Bioavailability at Contaminated Sites
(University of Waterloo, 2009-05-14)Contaminated areas resulting from anthropogenic activities have, for the most part, concentrations of contaminants that exceed Tier 1 standards below which the risk is considered acceptable. However, contaminants that have ... -
Assessing Taxonomic Issues with the Genera Anabaena, Aphanizomenon and Nostoc Using Morphology, 16S rRNA and efp genes
(University of Waterloo, 2009-01-08)Cyanobacteria are an ancient lineage of gram-negative photosynthetic prokaryotes that play an important role in the nitrogen cycle in terrestrial and aquatic systems. Widespread cyanobacterial blooms have prompted numerous ... -
Assessing the use of δ18O-PO4 analysis for tracing source inputs and the cycling of phosphorus: Applications to the Grand River
(University of Waterloo, 2014-05-01)The use of δ18O- PO4 analysis was assessed for the Grand River, a highly impacted river in Southern Ontario that receives inputs from 30 WWTPs. Significant nutrient inputs within the watershed have led to prolific aquatic ... -
An assessment of genomic sequence restoration in Arabidopsis thaliana
(University of Waterloo, 2009-08-27)A fundamental tenet of classical Mendelian genetics is that allelic information is stably transmitted from parent to progeny. Work in our laboratory has revealed a novel exception to this law where Arabidopsis thaliana ... -
An Assessment of Hydro-ecological Changes at Two Closed-drainage Basins in the Peace-Athabasca Delta, Alberta, Canada
(University of Waterloo, 2006)Diatom analyses were carried out on sediment cores collected from two low-lying, closed-drainage basins (PAD 9 - 58º46. 46?N, 111º19. 48?W; PAD 12 - 58º57. 29?, 111º19. 74?) in the Peace sector of the Peace-Athabasca ... -
Assessment of hydroecological changes at the Slave River Delta, NWT, using diatoms in seasonal, inter-annual and paleolimnological experiments
(University of Waterloo, 2007-09-27)Relationships between hydrology, limnology and ecology are analyzed in a comprehensive study of water bodies in the Slave River Delta, Northwest Territories, Canada, at a variety of temporal and spatial scales, including ... -
An Assessment of Pyridoxine as a Biological Response Modifier During Colon Carcinogenesis
(University of Waterloo, 2007-10-05)The main objective of this proposal was to investigate the effect of vitamin B6 on colon carcinogenesis in vivo. Two in vivo studies were conducted to determine the role of vitamin B6 as a biological modifier of colon ... -
Assessment of the cell cycle proteins Cdc7 and PCNA as markers of colon carcinogenesis in obese and lean rats
(University of Waterloo, 2009-11-23)Obesity increases the risk of colon cancer as well as the expression of many cancer markers, ostensibly due to the interaction between insulin resistance and adipocyte production of hormones, mitogens and cytokines which ... -
Assessment of toxic cyanobacterial abundance at Hamilton Harbour from analysis of sediment and water
(University of Waterloo, 2014-05-09)The western embayment of Lake Ontario, Hamilton Harbour, is one of the most polluted sites in the Laurentian Great Lakes and in recent years has seen a reoccurrence of cyanobacterial blooms. This study uses a multidisciplinary ... -
Association of Intersex in Wild Fish with Wastewater Effluent in the Grand River, Ontario
(University of Waterloo, 2012-02-10)The Grand River watershed is the largest watershed in southern Ontario, and is expected to see major development and urban densification over the next 20 years. An expected 57% increase in population over the next two ... -
Autophagic cell death during Drosophila embryogenesis
(University of Waterloo, 2012-01-23)The amnioserosa (AS) is an extraembryonic tissue that undergoes programmed cell death (PCD) during the normal course of Drosophila embryogenesis. AS degeneration involves morphological evidence of autophagy as well as ... -
Bacterial biogeography of the rare Charitable Research Reserve
(University of Waterloo, 2015-09-30)Soil microbial communities play a dominant role in global biogeochemical cycles, with profound effects on agriculture, ecosystem stability, human health, and global climate. As a result, assessing their biogeographic ... -
Bacterial Chromosome Engineering for Applications in Metabolic Engineering
(University of Waterloo, 2015-10-02)As genetic engineering technologies continue to advance and metabolic engineering projects become more ambitious, the need for chromosome engineering tools is increased. In this thesis, I have described the development of ...