Browsing Theses by Title
Now showing items 1835-1854 of 15724
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Characterization of the association of Dbf4 and Cdc7 with Mcm2-7 and chromatin in Saccharomyces cerevisiae.
(University of Waterloo, 2012-01-03)Initiation of DNA replication requires the action of the Dbf4/Cdc7 kinase complex (DDK) which is also a phosphorylation target of Rad53 kinase in the S-phase checkpoint. DDK is thought to trigger DNA replication by ... -
Characterization of the Behaviour of Solution-Responsive Polymers by Fluorescence
(University of Waterloo, 2014-04-17)Two families of amphiphilic polymers were characterized with respect to their ability to respond to changing solution conditions using steady-state and time-resolved fluorescence. Firstly, a series of 5 sequential amphiphilic ... -
Characterization of the chloroplast protein import receptors in the single-cell C4 species Bienertia sinuspersici
(University of Waterloo, 2012-04-25)Bienertia sinuspersici is one of the three currently known land plants which perform C4 photosynthesis without the conventional dual-cell system, but rather through intracellular compartmentation of organelles and enzymes ... -
Characterization of the Conformation and Internal Backbone Dynamics of a-Polyglucans by Pyrene Excimer Fluorescence
(University of Waterloo, 2021-11-23)The conformation and internal backbone dynamics (IBD) of several pyrene-labeled polysaccharides (Py-PSs), namely Py-Amylopectin, Py-Glycogen, Py-Dextran, and Py-Pullulan, were successfully examined with a combination of ... -
A characterization of the controls of the nitrogen and oxygen isotope ratios of biologically-produced nitrous oxide and nitrate in soils
(University of Waterloo, 2011-08-02)Nitrous oxide (N₂O) is a potent greenhouse gas, an important driver of climate change, and its concentration in the atmosphere is rising at an unprecedented rate. Agriculture is the leading contributor of all the anthropogenic ... -
Characterization of the critical biochemical and physiological role of 1-acylglycerol-3-phosphate-O-acyltransferase 4 (AGPAT4) in white adipose tissue
(University of Waterloo, 2016-08-18)White adipose tissue (WAT) is an endocrine and lipid storage organ that is imperative to mammals for the maintenance of energy homeostasis. WAT depot size and triacylglycerol (TAG) content is determined by the regulation ... -
Characterization of the Downstream Effects of the Rainbow Trout (Oncorhynchus mykiss) Chemokine, CK-2 on Macrophages
(University of Waterloo, 2010-05-25)Chemokines are chemotactic cytokines that have the ability to attract leukocytes and guide them via a concentration gradient to sites of injury/infection. These small, basic proteins are secreted when induced and act on ... -
Characterization of the effect of the menstrual cycle, estradiol and Fads2 transcript variants on fatty acid composition and enzyme expression
(University of Waterloo, 2016-08-29)Estrogen is believed to regulate fatty acid composition based on observations of differences between men and women, and changes associated with altered estrogen levels in women during pregnancy, menopause and hormone ... -
Characterization of the effects of sex, pregnancy, and 17β-estradiol on docosahexaenoic acid biosynthesis
(University of Waterloo, 2013-09-27)Docosahexaenoic acid (DHA) is an omega-3 polyunsaturated fatty acid (n-3 PUFA) required for fetal neurodevelopment. Increased DHA levels are associated with 17β-estradiol levels, as DHA is higher in women relative to men ... -
Characterization of the expression and function of <em>Rana catesbeiana</em> HSP30 and <em>Xenopus laevis</em> HSP27
(University of Waterloo, 2006)Exposure of cells to environmental or chemical stressors will initiate the heat shock response, which is mediated by heat shock proteins. Heat shock proteins are molecular chaperones which are classified by size into six ... -
Characterization of the FHA domain involved in Saccharomyces cerevisiae dNTP regulation.
(University of Waterloo, 2018-04-26)Over 2000 Forkhead-associated (FHA) domain-containing proteins exhibiting diverse functions, such as kinases, phosphatases, and transcription factors, have been identified to date in both eukaryotic and prokaryotic organisms. ... -
Characterization of the Human Plasma Macrolipidome using Standard Reference Material 1950 - Metabolites in frozen human plasma
(University of Waterloo, 2022-01-26)Standard Reference Material (SRM) 1950 Metabolites in frozen human plasma is a pooled plasma sample created by the National Institute of Standards and Technology (NIST) to be representative of plasma from the population ... -
Characterization of the Interactions Between DNA and Oppositely Charged Species by Fluorescence
(University of Waterloo, 2011-01-24)The characterization of the interactions between DNA and oppositely charged species were characterized by fluorescence. Quantitative and insightful information on the distribution of positively charged species around the ... -
Characterization of the Mechanical and Microstructural Properties of Thin Non-Orientated Electrical Steel Sheets
(University of Waterloo, 2023-01-03)With the rise and growth of electric vehicles, enhancing the design and implementation of electric engines in transportation vehicles is essential. Electric motors are an essential part of this enhancement. The material ... -
Characterization of the Mechanistic Roles of Rif1-Glc7 in DNA Double-Strand Break Repair Pathway Choice in Saccharomyces cerevisiae
(University of Waterloo, 2023-05-10)Rap-1 interacting factor 1 (Rif1) is a protein involved in telomere regulation, DNA replication and has more recently been found to mediate genomic stability by influencing the choice of DNA double-strand break (DSB) repair ... -
Characterization of the nodulation phenotype of E151, a pleiotropic pea (Pisum sativum L.) mutant.
(University of Waterloo, 2008-01-16)E151 (sym15) is characterized as a pleiotropic pea (Pisum sativum L.) mutant. It has been described as having short lateral roots, a short primary root, and a shorter epicotyl than that of the wild type Sparkle. Furthermore, ... -
Characterization of the Physical and Hydraulic Properties of Peat Impacted by a Temporary Access Road
(University of Waterloo, 2015-10-07)Due to the disruption of hydrology and water quality, permanent installation of roads and well pads is a practice that is discouraged. It is becoming more common to install temporary structures, which can subsequently be ... -
Characterization of the pro-apoptotic function of eIF5A in human cancer cell lines
(University of Waterloo, 2007-09-18)Eukaryotic translation initiation factor 5A (eIF5A) is the only known protein containing the unique amino acid, hypusine. eIF5A is present in all eukaryotic cells and is highly conserved, but its function is not well ... -
Characterization of the Quasi-Static and Fatigue Behavior of Forged AZ31B Magnesium Alloy
(University of Waterloo, 2018-04-17)Light-weighting is being aggressively targeted by automotive manufacturers as a method to reduce emissions. Magnesium (Mg) alloys due to their low density and high specific strength have therefore gained significant interest ... -
Characterization of the role of Orc6 in the cell cycle of the budding yeast <em>Saccharomyces cerevisiae</em>
(University of Waterloo, 2006)The heterohexameric origin recognition complex (ORC) acts as a scaffold for the G1 phase assembly of pre-replicative complexes. Only the Orc1-5 subunits are required for origin binding in budding yeast, yet Orc6 is an ...