Browsing Science (Faculty of) by Title
Now showing items 218-237 of 3018
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Beyond General Relativity: New Structure and Stability Predictions from Modified Gravity and High-Density Interaction Models
(University of Waterloo, 2022-09-29)In this thesis a number of topics are explored in an attempt to further understand gravitation and highly dense matter on a fundamental level. The notion of “quark stars” (QS), hypothetical compact stars composed of quark ... -
Bichromatic dressing of Rydberg atoms and on the correctness of many-mode Floquet theory
(University of Waterloo, 2020-01-20)Many-mode Floquet theory [T.-S. Ho, S.-I. Chu, and J. V. Tietz, Chem. Phys. Lett. 96, 464 (1983)] was designed as an extension of Floquet theory suitable for solving the time-dependent Schrodinger equation with multiple ... -
Bidirectional mapping between self-consistent field theory and molecular dynamics
(AIP Publishing, 2007-10-08)A bidirectional mapping scheme that bridges particle-based and field-based descriptions for polymers is presented. Initial application is made to immiscible homopolymer blends. The forward mapping (upscaling) approach ... -
Bifocals in children with Down syndrome (BiDS)
(University of Waterloo, 2010-07-28)Down syndrome (DS) is the most common genetic cause of mental challenge in individuals and is associated with many ocular disorders. One of these anomalies which is frequently present in this population is reduced accommodation ... -
Binding of Au3+ Ions by Polyadenine DNA
(University of Waterloo, 2020-09-02)Interactions between DNA and metal ions are important for many applications such as metal sensing, therapeutics and nanotechnology. Many studies have already been published on these topics. DNA can bind metal ions via its ... -
Binocular Adaptation to +2 D Lenses in Myopic and Emmetropic Children:
(Wolters Kluwer, 2009-06)Purpose. To compare vergence adaptation to +2 D addition lenses in myopic and emmetropic children and to evaluate the influence of the accommodative-vergence crosslink (AC/A ratio) on this adaptation. Methods. Nine ... -
Binocular adaptation to near addition lenses in emmetropic adults
(Elsevier, 2008-05)Near addition lenses are prescribed to pre-presbyopic individuals for treatment of binocular motor problems such as convergence excess and to control the progression of myopia. To date, no investigation has looked at the ... -
Binocular treatment of amblyopia using videogames (BRAVO): study protocol for a randomised controlled trial
(BioMed Central, 2016-10-18)Amblyopia is a common neurodevelopmental disorder of vision that is characterised by visual impairment in one eye and compromised binocular visual function. Existing evidence-based treatments for children include patching ... -
Binocular vision and fixational eye movements
(University of Waterloo, 2017-07-19)Introduction In observers with amblyopia, abnormal patterns of amblyopic eye (AME) fixational eye movements (FEM) have been associated with monocular (reduced amblyopic eye visual acuity) and binocular sensory deficits ... -
Bio-optical Modeling of Aquatic Photosynthesis in the Laurentian Great Lakes
(University of Waterloo, 2010-05-19)The methodology of phytoplankton production measurements in the Laurentian Great Lakes and other freshwater lakes has remained largely unchanged in the past 40 years. In most studies photosynthesis from a single water ... -
Biochemical and Biophysical Investigations of Non-Zinc Dependent Glyoxalase I Enzymes
(University of Waterloo, 2008-09-26)The principal methylglyoxal (MG)-detoxifying system in most living organisms is the two metalloenzyme Glyoxalase system. Glyoxalase I (GlxI) initially converts the non-enzymatically formed MG-GSH hemithioacetal to the ... -
Biochemical and Microbiological Investigations of Inhibitors for β-Lactamases from Human Pathogenic Bacteria
(University of Waterloo, 2019-04-30)The majority of antibiotics prescribed for treatment of bacterial infections are β-lactam antibiotics. Resistance to these has evolved in a few different ways, notably by regulating permeability and by the expression of ... -
Biochemical Characterization and Optimization of RNA Aptamers Bound to Hoechst Dye Derivatives
(University of Waterloo, 2023-08-09)Ribonucleic acid (RNA) aptamers are single-stranded nucleic acids that are typically selected through a process known as Systematic Evolution of Ligands by EXponential Enrichment (SELEX). These oligonucleotides can bind ... -
Biochemical Characterization of a Lanthanide-Dependent DNAzyme with Normal and Phosphorothioate-Modified Substrates
(American Chemical Society, 2015-10-06)A trivalent lanthanide (Ln3+)-dependent RNA-cleaving DNAzyme, Ce13d, was recently isolated via in vitro selection. Ce13d is active in the presence of all Ln3+ ions. Via introduction of a single phosphorothioate (PS) ... -
Biochemical Characterization of Fluorophore-Binding Nucleic Acids
(University of Waterloo, 2022-09-27)Aptamers, single stranded RNA or DNA that bind to target ligands with high affinity and specificity, have a wide range of applications, from therapeutics to biosensing, which makes biochemical characterization of the utmost ... -
Biochemical Investigations of L-Methionine gamma-lyase 1 from Trichomonas vaginalis
(University of Waterloo, 2011-12-16)The enzyme L-methionine γ-lyase (MGL) utilizes a pyridoxal-5’-phosphate-cofactor in order to convert L-methionine to α-ketobutyrate, ammonia and methyl mercaptan. MGL is proposed to be a potential drug target since it is ... -
Biochemistry in Bacterioferritin
(University of Waterloo, 2006)Bacterioferritin, an iron storage protein having a 24-subunit quaternary structure, was used as a model for the study of host-guest interactions and guest encapsulation, making use of its spherical cage-like structure. ... -
BIOCOMPATIBLE SOLID PHASE MICROEXTRACTION
(University of Waterloo, 2006-12-12)Today’s solid phase microextraction (SPME) is a well known technique that combines knowledge from different fields in an attractive, efficient, and economic way. The development of SPME has seen huge growth since its ... -
Biocompatible Solid-Phase Microextraction Nanoelectrospray Ionization: An Unexploited Tool in Bioanalysis
(American Chemical Society, 2015-12-09)In recent years, different geometrical configurations of solid-phase microextraction (SPME) have been directly coupled to mass spectrometry, resulting in benefits such as diminishing matrix effects, improvement of detection ... -
Bioenergetics of mixotrophic metabolisms: A theoretical analysis
(University of Waterloo, 2019-08-29)Many biogeochemical reactions controlling surface water and groundwater quality, as well as greenhouse gas emissions and carbon turnover rates, are catalyzed by microorganisms. Representing the thermodynamic (or bioenergetic) ...