Browsing Science (Faculty of) by Title
Now showing items 2111-2130 of 3045
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Physicochemical and Vegetative Responses of Prairie Wetlands to Local Land Covers
(University of Waterloo, 2016-09-28)Effective environmental monitoring and biological assessment initiatives require knowledge of the spatial and temporal scales at which human activities most strongly influence ecosystem conditions. I compared the environmental ... -
Physicochemical properties of isolated biomolecule clusters
(University of Waterloo, 2017-09-27)An investigation of the physicochemical properties of isolated biomolecule clusters is herein described. Three distinct subprojects examine (a) the role several complex organic ligands may play in the promotion or disruption ... -
Physics in Higher-Dimensional Manifolds
(University of Waterloo, 2003)In this thesis, we study various aspects of physics in higher-dimensional manifolds involving a single extra dimension. After giving some historical perspective on the motivation for studying higher-dimensional theories ... -
The physiological ecology of preparing for and recovering from hibernation in temperate insectivorous bats
(University of Waterloo, 2023-01-12)Temperate insectivorous bats that hibernate must both prepare for and recover from hibernation during times of the year with low resource abundance and low ambient temperatures, resulting in energetic bottlenecks in both ... -
Physiologically based Pharmacokinetic (PBPK) Modelling of Cisplatin in Rats and Humans
(University of Waterloo, 2019-10-17)The physiologically based pharmacokinetic (PBPK) modelling has been accepted as one of the most effective mechanistic techniques to analyze pharmacokinetics (PK) of drugs in the drug development process. Its effectiveness ... -
Physiologically Based Pharmacokinetic Modeling of Monoclonal Antibodies in Children
(University of Waterloo, 2021-06-25)The following thesis chapters chronicle evolving efforts throughout 2016 – 2021 to support research toward improving the pediatric clinical pharmacology of monoclonal antibodies (mAbs). Translating the benefits of successful ... -
Physiologically-based pharmacokinetic model for ciprofloxacin in children with complicated urinary tract infection
(Elsevier, 2019-02-01)In a recent multicenter population pharmacokinetic study of ciprofloxacin administered to children suffering from complicated urinary tract infection (cUTI), the apparent volume of distribution (V) and total plasma clearance ... -
Phytanyl substituted asymmetric gemini surfactant-based transfection vectors for gene therapy
(University of Waterloo, 2013-08-02)To achieve successful gene therapy, safe and efficient gene delivery vectors are needed. As an alternative to viral vectors, non-viral vectors, incorporating compounds such as cationic polymers and lipids have been widely ... -
Phytoplankton community composition effects on phosphorus sedimentation dynamics in Lake Erie
(University of Waterloo, 2007-10-01)Cultural eutrophication is caused by the excess addition of phosphorus to aquatic ecosystems, and has long been a water quality management issue in Lake Erie. Despite successful reductions in external loading of phosphorus ... -
Phytoplankton dynamics in nearshore and offshore regions of the Great Lakes Erie, Malawi, Tanganyika, and Victoria
(University of Waterloo, 2008-02-22)My doctoral thesis challenges the traditional paradigm of phosphorus (P) limitation of phytoplankton communities in freshwaters by suggesting colimitation of P, nitrogen (N), and iron (Fe) in Great Lakes. Oceanographers ... -
Phytoplankton Production In Lake Victoria, East Africa
(University of Waterloo, 2004)This thesis develops, validates and applies an empirical model that provides the first spatially explicit estimates of gross and net phytoplankton production in Lake Victoria. Gross and net phytoplankton production are ... -
A Picture is Worth a Thousand Words: A Randomized Controlled Trial to Assess the Impact of a Computerized Pictorial Medication Calendar Medication Taking Behaviour
(University of Waterloo, 2017-08-11)OBJECTIVES The primary was to determine if a pictorial medication calendar would improve patient adherence to supportive medication regimens for adult patients receiving chemotherapy treatment. The secondary objectives ... -
Piperine Derivatives as Modulators of Amyloid-Beta (Aβ) Aggregation
(University of Waterloo, 2023-07-12)Alzheimer’s Disease (AD) is a life-changing neurodegenerative disease that progresses in stages and currently has no effective cure. More than 597,000 Canadians suffer from AD. Symptoms of late-stage AD are severe and ... -
Pituitary adenylate cyclase-activating polypeptide (PACAP) as a treatment for microbial infections in rainbow trout (Oncorhynchus mykiss) aquaculture
(University of Waterloo, 2021-09-28)Diseases cause economic losses in aquaculture, and the widespread use of antibiotics in the industry has contributed to the development of antibiotic resistant pathogens, an issue of concern for its repercussions on the ... -
The pivotal role of angiogenesis in a multi-scale modeling of tumor growth exhibiting the avascular and vascular phases
(Elsevier, 2018-09-01)The mechanisms involved in tumor growth mainly occur at the microenvironment, where the interactions between the intracellular, intercellular and extracellular scales mediate the dynamics of tumor. In this work, we present ... -
Placing Limits on Light Axions with EHT Polarimetry via Closure Traces
(University of Waterloo, 2023-08-31)Black holes can amplify incoming bosonic waves via rotational superradiance, inducing bound states of ultralight bosons around them. This phenomenon has the potential to confine the parameter spaces of new bosons. Axions, ... -
Plankton Metabolic Balance and its Controlling Factors in the Coastal Zone of the Laurentian Great Lakes
(University of Waterloo, 2007-10-01)Plankton metabolic balance (PMBm) of the surface mixed layer was calculated as the ratio of areal rates of gross photosynthesis (AGP) to community respiration (AR), and estimated for four Laurentian Great Lakes coastal ... -
Plant Growth-Promoting Bacterial Endophytes that contain ACC Deaminase: Isolation, Characterization, and Use
(University of Waterloo, 2013-04-26)Bacteria that provide benefit to plants are considered to be plant growth-promoting bacteria (PGPB) and can facilitate plant growth by a number of different mechanisms. Plant growth-promoting bacteria that are able to ... -
Plant Growth-Promoting Rhizobacteria (PGPR) Enhanced Phytoremediation of DDT Contaminated Soil
(University of Waterloo, 2008-05-21)Although the pesticide DDT has been banned from use in Canada for more than three decades, DDT still persists in Canadian farmlands at detectable levels. Much effort, such as incineration, thermal desorption, and bioremediation, ... -
Plant growth-promoting root-colonizing bacterial endophytes
(Elsevier, 2021-12)The development of an environmentally friendly agricultural system as opposed to conventional methods using chemical fertilizers and pesticides for improved crop productivity is a promising aspect of modern agricultural ...