Browsing Theses by Subject "metabolism"
Now showing items 1-15 of 15
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Changes in Gill Physiology and Energy Requirements of Darter Species (Etheostoma spp.) due to Effluent in the Grand River
(University of Waterloo, 2020-08-18)The effluent from municipal wastewater treatment plants is a major point source of contamination in Canadian waterways. Improvement of effluent quality to reduce contaminants like pharmaceuticals and personal care products, ... -
Characterization of the effect of the menstrual cycle, estradiol and Fads2 transcript variants on fatty acid composition and enzyme expression
(University of Waterloo, 2016-08-29)Estrogen is believed to regulate fatty acid composition based on observations of differences between men and women, and changes associated with altered estrogen levels in women during pregnancy, menopause and hormone ... -
The Effect of Unbalanced Dietary Methionine fed to Pregnant Rats on Maternal and Fetal One-Carbon Metabolism
(University of Waterloo, 2012-04-02)Protein restriction during rodent pregnancy is a well-established model of developmental programming. Although the Southampton low-protein diet model of developmental programming has been accepted to produce hypertensive ... -
Growth and regulatory metabolism of cellulose-utilizing thermophilic Caldicellulosiruptor species
(University of Waterloo, 2015-05-19)Hydrogen biofuels have been proposed as an environmentally-friendly and renewable energy substitute for petroleum-based fossil fuels. One species of bacteria capable of degrading cellulosic materials and producing vast ... -
A Hybrid Cellular Automata Model for the Role of Reactive Oxygen Species in Novel Tumour Treatments Strategies
(University of Waterloo, 2015-01-21)Cancer is a disease that entails uncontrolled proliferation and a disruption of tissue function that often results in a poor clinical outcome. Furthermore, it has continued to elude any universal treatment or cure in part ... -
Impact of the antidepressant venlafaxine on the hypothalamus-pituitary-interrenal axis function in rainbow trout
(University of Waterloo, 2014-05-27)Over the recent years, venlafaxine has become the predominant antidepressant drug detected in municipal wastewater effluents (MWWE) and aquatic systems. However, very little is known about the effect of this drug in the ... -
Impairments in glucose and lipid metabolism in breast cancer patients
(University of Waterloo, 2013-01-08)BACKGROUND: Breast cancer patients typically present with unhealthy body composition (high fat mass and low muscularity) near diagnosis. These body composition characteristics often worsen during treatment and ultimately ... -
The Influence of Low-Load High-Repetition Resistance Exercise and Sex on the Metabolic Properties of Skeletal Muscle
(University of Waterloo, 2020-02-04)INTRODUCTION. The findings of exercise trials have shown that women are better able to initiate aerobic metabolism and are less reliant on anaerobic energy stores. The effect that LL-HR resistance exercise and sex has on ... -
Micromeda: a genome property prediction pipeline and web visualization tool
(University of Waterloo, 2020-05-07)Understanding the distribution of biochemical pathways across microorganisms is critical to understanding these organism's evolution, ecology, and industrial applicability. Advances in genome sequencing and pathway databases ... -
Multi-stressor impacts on fish energetics and stress response: a comparison between lab and field studies
(University of Waterloo, 2017-08-24)Aquatic organisms are continuously exposed to multiple environmental stressors that work cumulatively and synergistically to alter ecosystems. The objective of this study was to investigate the impacts of multiple stressors ... -
Phenotypic Characterization of the Male Tafazzin-Knockout Mouse Model of Barth Syndrome at 3-, 6-, and 12-Months of Age
(University of Waterloo, 2022-05-18)Barth Syndrome (BTHS) is a devastating disorder caused by mutations in the gene encoding for Tafazzin (TAZ), a key enzyme involved in the biosynthesis of the phospholipid cardiolipin, which is vital for maintaining the ... -
Rat, Plastic, Wood
(University of Waterloo, 2021-08-19)Rat, Plastic, Wood is an exhibition of hybrid sculptures centering the physical manifestation of interspecies intra-action and natural forms of contamination-as-collaboration. In the gallery space a central structure of ... -
ROLE OF SECOND MESSENGER SIGNALING PATHWAYS IN THE REGULATION OF SARCOPLASMIC RETICULUM CALCIUM-HANDLING PROPERTIES IN THE LEFT VENTRICLE AND SKELETAL MUSCLES OF DIFFERENT FIBRE TYPE COMPOSITION
(University of Waterloo, 2007-02-09)The overall objective of this thesis was to examine mechanisms involved in the acute regulation of sarcoplasmic reticulum (SR) Ca2+-handling properties by second messenger signaling pathways in skeletal and cardiac muscle. ... -
Sex-based differences in IMCL storage and utilization during an acute bout of high intensity interval exercise (HIIE)
(University of Waterloo, 2023-09-21)INTRODUCTION: The contribution of lipids, particularly intramyocellular lipids (IMCL), to energy production during high intensity interval exercise (HIIE) is not well characterized. Sex influences lipid utilization during ... -
Understanding the Sf9 – Baculovirus Expression Vector System: Exploring the Metabolic Basis of the Cell Density Effect through Nuclear Magnetic Resonance Spectroscopy and Flow Cytometry Analysis of Fluorescent Protein Accumulation
(University of Waterloo, 2020-05-15)It is well established that the baculovirus expression vector system (BEVS) can serve as an important, effective production system for various biologicals. Knowing that the cells can serve as a production platform is ...