Browsing Science (Faculty of) by Title
Now showing items 603-622 of 3023
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Design and Implementation of the Real-Time Control System for an Open Trapped Ion Quantum Computing Platform
(University of Waterloo, 2023-09-08)Trapped atomic ions are a promising platform for the implementation of quantum bits and quantum information processors due to advantageous inherent physical properties as well as exquisite experimental control. Trapped ion ... -
Design of a DNA-Encoded Human Papilloma Virus-Like Particle Displaying a Vascular Endothelial Growth Factor Antagonistic Peptide for Characterization in Mammalian Cells
(University of Waterloo, 2022-12-21)Cancer immunotherapy has evolved as an effective platform for the treatment of a variety of cancer types by enhancing and/or modulating the functionality of the immune system to target cancer cells and consequently mitigate ... -
Design of a Real-Time Embedded Control System for Quantum Computing Experiments
(University of Waterloo, 2020-01-27)This thesis describes the design of a real-time control system for trapped ion quantum computer experiments. It is framed in the context of the QuantumIon project, a project at the University of Waterloo’s ... -
Design of an Inverse Photoemission Spectrometer for the Study of Strongly Correlated Materials
(University of Waterloo, 2013-01-23)The design and construction of a state-of-the-art ultra-high vacuum spectrometer for the performance of angle-resolved inverse photoemission spectroscopy is presented. Detailed descriptions of its most important components ... -
The Design Of An Out-Diffusion Experiment And The Use Of Geochemical Analyses For The Purpose Of Matrix Pore Fluid Extraction And Characterization: A Case Study For Radioactive Waste Disposal
(University of Waterloo, 2008-04-30)Deep crystalline rock formations of low permeability have been identified as a possible geological medium for high-level radioactive waste disposal. In order for the safe disposal of radioactive waste, a site characterization ... -
Design of efficient block-sparse data structures and associated tensor multiplications for applications in Cluster in Molecule electronic structure calculations
(University of Waterloo, 2022-08-18)The Cluster-in-molecule approach (CiM) is one of the most popular methods in electronic structure calculations for medium to large molecules and systems. The Nooijen group is currently developing a new CiM approach using ... -
Design Strategy of 2D Material Field-Effect Transistors: Engineering the Number of Layers in Phosphorene FETs
(AIP Publishing, 2016-06-07)Thickness or the number of layers in 2D semiconductors is a key parameter to determine the material’s electronic properties and the overall device performance of 2D material electronics. Here we discuss the engineering ... -
Design, characterization, optical and photophysical properties of novel thiophene monomers and polymers containing pyrene moieties linked via rigid and flexible spacers
(Elsevier, 2019-02-01)Herein, we report the synthesis of three novel thiophene monomers connected to pyrene moieties via a flexible oligo(ethylene glycol) (OEG) spacer with an oxygen -to-pyrene (T1), a flexible OEG spacer with an oxygen ... -
Design, construction and characterization of LysK endolysin display phage against Staphylococcus aureus
(University of Waterloo, 2014-02-04)The growing threat of drug- resistant Staphylococcus aureus (S. aureus) infections mandates the need to develop novel, effective and alternative antibacterial therapeutics. Despite infection prevention and control measures, ... -
Design, Synthesis and Biological Evaluation of 2,4-Disubstituted Pyrimidine Derivatives: Multifunctional Candidates as Potential Treatment Options for Alzheimer’s Disease
(University of Waterloo, 2011-08-30)Alzheimer’s disease (AD) is a highly complex and rapidly progressive neurodegenerative disorder characterized by the systemic collapse of cognitive function and formation of dense amyloid-β (Aβ) plaques and neurofibrillary ... -
Design, Synthesis and Biological Evaluation of Novel Adamantane Derivatives as Potential Treatments for Alzheimer’s Disease
(University of Waterloo, 2017-02-14)Alzheimer’s disease (AD) is a complex, multifactorial, and rapidly neurodegenerative disorder characterized by cognitive impairment and progressive dementia. Its pathology was first characterized by Alois Alzheimer as “a ... -
Design, synthesis and biological evaluation of novel tricyclics as dual cholinesterase (ChE) and amyloid aggregation inhibitors with antioxidant properties
(University of Waterloo, 2014-12-12)Alzheimer’s disease (AD) is a complex neurodegenerative disease affecting the cholinergic region of the brain. Its prevalence is steadily increasing and it is becoming one of the highest costing diseases to modern society. ... -
Design, Synthesis and Characterization of a Series of Self-assembling Polypeptides
(University of Waterloo, 2007-05-24)A series of polypeptides with well-defined sequences, (Asp3Phe1)n, (Asp2Phe1)n, (Asp1Phe1)n, (Asp1Phe2)n, and (Asp1Phe3)n, containing the hydrophilic amino acid, aspartic acid (Asp) and the hydrophobic amino acid, phenylalanine ... -
Design, synthesis, and evaluation of inhibitors of steroid sulfatase
(University of Waterloo, 2014-04-22)Steroid sulfatase (STS) catalyzes the desulfation of biologically inactive sulfated steroids to yield biologically active desulfated steroids and is currently being examined as a target for therapeutic intervention for the ... -
Design, Synthesis, and Evaluation of Tacrine-Based Derivatives: Potential Agents to Treat Alzheimer’s Disease
(University of Waterloo, 2013-08-01)With the incidence of Alzheimer’s disease (AD) growing worldwide and in Canada along with the growing economic and social burdens, the need for more effective therapies becomes of great importance. Since the discovery of ... -
Desulfurization Activated Phosphorothioate DNAzyme for the Detection of Thallium
(American Chemical Society, 2015-10-20)Thallium (Tl) is a highly toxic heavy metal situated between mercury and lead in the periodic table. While its neighbors have been thoroughly studied for DNA-based sensing, little is known about thallium detection. In this ... -
A detailed hydrologic evaluation of tile-drained macroporous soils: A field and modelling study
(University of Waterloo, 2011-03-07)The underlying objective of this research is to improve the overall understanding of how spatial and temporal variability in macroporosity and soil hydraulic properties in the shallow subsurface influence the long term ... -
Detecting the effects of biological invasion and subsequent control efforts on wetland ecological processes
(University of Waterloo, 2018-09-21)Meadow and emergent cattail wetland communities in eastern North America are being replaced by an invasive lineage of <i>Phragmites australis</i>. This invasion has consequences for wetland ecosystem functions; including ... -
Detecting the Surface Spin Polarization State of Topological Materials by Using Resonant X-ray Reflectometry
(University of Waterloo, 2019-10-21)The topological insulator as a promising and low cost next generation spintronic device attracts lots of attentions recently. The spin-momentum locking is a characteristic feature of topological materials at the surface ... -
Detection Efficiency Mismatch and Finite-Key-Size Attacks on Practical Quantum Cryptography Systems
(University of Waterloo, 2016-01-14)Security verification for the physical implementation of a cryptography system is an important step to ensure the security level promised by theory. As has been shown many times, any physical device has characteristics and ...