Browsing Kinesiology and Health Sciences by Type "Master Thesis"
Now showing items 21-40 of 286
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Cerebral Autoregulatory Response to Postural Changes and Walking in Older Adults with Heart Failure
(University of Waterloo, 2019-09-18)Individuals with heart failure (HF) have reduced cerebral blood flow (CBF) compared to age- matched older adults. This might be related to an impairment in cerebral autoregulation (CA), or an impairment in the CA mechanisms ... -
Cerebral Blood Flow Response to Posture Transition and Walking in Older Adults with Heart Failure
(University of Waterloo, 2019-08-29)Individuals with heart failure (HF) have lower cerebral blood flow (CBF) and oxygenation at rest, and lower cerebral oxygenation at peak exercise, likely due to insufficient cardiac output and poor respiratory function; ... -
Cerebrovascular and cardiovascular responses to lower body negative pressure and posture change in the elderly
(University of Waterloo, 2012-08-27)Lower body negative pressure (LBNP) is frequently used in the research setting as a means to induce orthostatic stress. This tool is applicable to typical movements during daily living only if the associated responses are ... -
Changes in Conduit Artery Blood Flow and Diameter Post Blood Flow Restriction
(University of Waterloo, 2011-04-19)Flow mediated dilation (FMD) is a non-invasive test that assesses endothelial health and nitric oxide bioavailability; it is commonly used to examine changes in vascular health due to disease or de-conditioning. Currently, ... -
Changes in Physical Activity, Physical Function and Cognitive Function with Transition to Retirement Living
(University of Waterloo, 2014-08-01)Physical activity is associated with slower physical and cognitive decline with aging. However, there are many barriers to physical activity among community-dwelling older adults. Retirement living may facilitate physical ... -
Characterization of a novel truncated isoform of murine AGPAT4 arising from predicted splice variants
(University of Waterloo, 2021-06-02)The acylglycerophosphate acyltransferase (AGPAT)/lysophosphatidic acid acyltransferase (LPAAT) family of enzymes is responsible for the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor of ... -
Characterization of Changes in the Kidney, Liver, and Adipose Tissue of RTSAKO Mice
(University of Waterloo, 2018-11-02)Our laboratory has developed a novel genetic mouse model with kidney-specific lipid accumulation called RTSAKOs. The principle aim of my thesis was to study differences in the expression of genes and proteins related to ... -
Characterization of murine HRASLS-1: transcript variant analysis, metabolic regulation, developmental expression, and a role in inflammation
(University of Waterloo, 2014-08-27)N-acylethanolamides (NAE) are involved in a variety of biological processes ranging from fat oxidation to inflammation mediation. Recently, the HRASLS family, a group of class II tumour suppressor proteins, have been ... -
Characterization of the critical biochemical and physiological role of 1-acylglycerol-3-phosphate-O-acyltransferase 4 (AGPAT4) in white adipose tissue
(University of Waterloo, 2016-08-18)White adipose tissue (WAT) is an endocrine and lipid storage organ that is imperative to mammals for the maintenance of energy homeostasis. WAT depot size and triacylglycerol (TAG) content is determined by the regulation ... -
Characterization of the Human Plasma Macrolipidome using Standard Reference Material 1950 - Metabolites in frozen human plasma
(University of Waterloo, 2022-01-26)Standard Reference Material (SRM) 1950 Metabolites in frozen human plasma is a pooled plasma sample created by the National Institute of Standards and Technology (NIST) to be representative of plasma from the population ... -
Characterizing Sex Differences in Lipid Metabolism during an Acute, 30-Minute Bout of Moderate- Intensity Continuous (MIC) Exercise
(University of Waterloo, 2021-01-05)INTRODUCTION: Increased intramyocellular lipid (IMCL) size and storage in the subsarcolemmal region of the myocyte are associated with insulin resistance (IR) and the development of type 2 diabetes (T2D). Women have a ... -
Characterizing Sex Differences in Skeletal Muscle Anaerobic Metabolism during an Acute Bout of High Intensity Interval Exercise
(University of Waterloo, 2020-09-03)INTRODUCTION: Exercise is known to improve insulin sensitivity (IS); however, its effectiveness may be absent or blunted in women, particularly following high intensity interval (HII) training. Sex differences in anaerobic ... -
Characterizing the Biomechanical Exposures Associated with Common and High Demand Personal Support Worker Tasks
(University of Waterloo, 2023-08-31)Background: The physical demands that personal support workers (PSWs) are exposed to are increasing as our population ages and our society is increasingly shifting to at-home care, resulting in increases in workload ... -
Characterizing the dynamics of vestibular reflex gain modulation using balance-relevant sensory conflict
(University of Waterloo, 2023-09-21)Electrical vestibular stimulation (EVS) can be used to evoke reflexive body sways as a probe of vestibular control of balance. However, EVS introduces sensory conflict by decoupling vestibular input from actual body motion, ... -
Characterizing the Role of Phospholamban in Duchenne Muscular Dystrophy
(University of Waterloo, 2018-01-16)Duchenne muscular dystrophy (DMD) and the murine model, mdx, are recessive X-linked myopathies characterized by aberrant Ca2+-handling resulting in muscle atrophy and weakness. Phospholamban (PLN) is a protein inhibitor ... -
Characterizing the Variability of Kinematic Outcome Measures and Compensatory Movements using Inertial Measurement Units
(University of Waterloo, 2019-01-22)Cost-effective wearable sensors to measure movement have gained traction as research and clinical tools. The potential to quantify movement with a portable and inexpensive way could provide benefits to patient populations ... -
Clinical assessment of body composition after spinal cord injury. An observational study.
(University of Waterloo, 2009-11-19)Background: Persons who sustain a spinal cord injury (SCI) experience a dramatic loss of muscle and bone, and a dramatic increase in adipose tissue. It has been suggested that the muscle atrophy, obesity, and sublesional ... -
Coded Hemodynamic Imaging of the Jugular Vein and Ultrasound Imaging of the Optic Nerve Sheath Diameter during Manipulations of Intracranial Pressure by Head-Down Tilt
(University of Waterloo, 2020-08-21)Background: Spaceflight associated neuro-ocular syndrome (SANS) is a condition in which worsening vision occurs while in microgravity. It has been hypothesized that SANS is caused by an increase in intracranial pressure ... -
Combined cognitive and exercise training for community-dwelling adults and older adults: A feasibility study
(University of Waterloo, 2020-08-31)Older adults show cognitive improvements after taking part in exercise training or cognitive training. A number of studies suggest that combining these two types of interventions may lead to greater cognitive gains. However, ... -
Comparing knee joint kinematics, kinetics and cumulative load between healthy-weight and obese young adults
(University of Waterloo, 2011-05-20)One of the most poorly understood co-morbidities associated with obesity is the pathway to osteoarthritis of the knee. To implement appropriate preventative strategies, it is important to explore how obesity is a causal ...