Browsing Theses by Supervisor "Hughson, Richard"
Now showing items 1-10 of 10
-
Cerebral Autoregulatory Response to Postural Changes and Walking in Older Adults with Heart Failure
(University of Waterloo, 2019-09-18)Individuals with heart failure (HF) have reduced cerebral blood flow (CBF) compared to age- matched older adults. This might be related to an impairment in cerebral autoregulation (CA), or an impairment in the CA mechanisms ... -
Cerebral Blood Flow Response to Posture Transition and Walking in Older Adults with Heart Failure
(University of Waterloo, 2019-08-29)Individuals with heart failure (HF) have lower cerebral blood flow (CBF) and oxygenation at rest, and lower cerebral oxygenation at peak exercise, likely due to insufficient cardiac output and poor respiratory function; ... -
Cerebrovascular Hemodynamics, Postural Stability, Gait Dynamics, and Falls in Older Adults
(University of Waterloo, 2018-04-26)Injurious falls in community-living older adults are associated with standing up suggesting that cerebral hypoperfusion following a postural transition might be a contributing factor. A large population study has recently ... -
Coded Hemodynamic Imaging of the Jugular Vein and Ultrasound Imaging of the Optic Nerve Sheath Diameter during Manipulations of Intracranial Pressure by Head-Down Tilt
(University of Waterloo, 2020-08-21)Background: Spaceflight associated neuro-ocular syndrome (SANS) is a condition in which worsening vision occurs while in microgravity. It has been hypothesized that SANS is caused by an increase in intracranial pressure ... -
The Effect of Spironolactone on Cerebral Blood Flow and Cognition
(University of Waterloo, 2018-03-23)Hypertension and arterial stiffness are associated with structural and functional changes in cerebral circulation and cognitive function, but based on existing evidence the effects are potentially reversible by spironolactone ... -
Hemodynamic effects of intermittent compression as a countermeasure to orthostatic stress
(University of Waterloo, 2017-09-05)Upright posture can be associated with symptoms of dizziness, light-headedness and blurred vision, which are fundamentally caused by impaired cerebral hemodynamics. As gravity acts along the body’s longitudinal axis, pooling ... -
Prediction of Oxygen Uptake and its Dynamics by Wearable Sensors During Activities of Daily Living
(University of Waterloo, 2016-12-21)The evaluation of the aerobic response to a new energetic demand provides valuable information regarding the functional capabilities of the aerobic system. Abnormal, or impaired aerobic responses may occur before the ... -
Regional Cerebral Blood Flow Differences Between the Middle Cerebral Artery and the Basilar Artery
(University of Waterloo, 2017-09-27)Much of the research that has investigated cerebral circulation has used the MCA and has assumed that it is an indicator of what is happening in all regions of the brain. Yet little research exists to validate this notion. ... -
The Role of Activities of Daily Living in Healthy Vascular Aging
(University of Waterloo, 2022-01-05)Normal aging leads to endothelial dysfunction and arterial stiffening implicated in cognitive decline. Cerebral blood flow also declines with aging. Elevated blood flow during exercise produces laminar shear stress which ... -
Wearable Sensor Technology and Machine Learning for Prediction of Oxygen Uptake and Extraction of Kinetics during Moderate and Heavy Intensity Exercise
(University of Waterloo, 2020-08-19)The speed at which pulmonary oxygen uptake (V̇O2p) responds to a change in energetic demand provides information about an individual’s health and functional capabilities. Advances in wearable sensor technology and machine ...