Now showing items 48-67 of 246

    • A Computational Model for Predicting Visual Acuity from Wavefront Aberration Measurements 

      Faylienejad, Azadeh (University of Waterloo, 2009-09-14)
      The main purpose of this thesis is to create and validate a visual acuity model with experimentally obtained aberrations of human eyes. The other motivation is to come up with a methodology to objectively predict the ...
    • Computerized and Non-Computerized Colour Vision Tests 

      Almustanyir, Ali (University of Waterloo, 2014-08-05)
      Introduction: Measuring colour discrimination of people who carry out tasks where colour is used to convey information and accurate colour judgments are essential for safe and efficient performance of the task is important ...
    • Contact lens fitting characteristics and comfort with silicone hydrogel lenses 

      Maram, Jyotsna (University of Waterloo, 2012-02-24)
      Purpose To examine soft contact lens fitting characteristics using anterior segment imaging techniques and comfort. The specific aims of each chapter are as follows: Chapter 2: To calibrate the new ZEISS VisanteTM ...
    • Contact lens physical properties and lipid deposition in a novel characterized artificial tear solution 

      Lorentz, Holly; Heynen, Miriam L.; Kay, Lise M. M.; Dominici, Claudia Y.; Khan, Warda; Ng, Wendy W. S.; Jones, Lyndon W. (Molecular Vision, 2011-12-24)
      Purpose: To characterize various properties of a physiologically-relevant artificial tear solution (ATS) containing a range of tear film components within a complex salt solution, and to measure contact lens parameters and ...
    • Contact Lenses and Tear Film Lipids. 

      Walther, Hendrik (University of Waterloo, 2017-12-20)
      Introduction Lipids are essential tear components that aid the stability of the tear film (TF) to protect it from excess evaporation. The composition, conformation, and function of TF lipids are jeopardized by external ...
    • Contact Lenses for Ciprofloxacin Drug Delivery 

      Hui, Alex (University of Waterloo, 2014-07-31)
      PURPOSE The purpose of this thesis was to evaluate the potential of contact lenses as ciprofloxacin drug delivery devices. METHODS Investigations into ciprofloxacin uptake and release characteristics, and the possibility ...
    • Contemporary Diagnosis and Management of Dry Eye 

      Ngo, William (University of Waterloo, 2016-08-31)
      Introduction Dry eye (DE) disease is characterized by symptoms including, but not limited to, ocular stinging, burning, and tearing. The symptoms can range from being mildly irritating, to severely debilitating and ...
    • Controlling “chemical nose” biosensor characteristics by modulating gold nanoparticle shape and concentration 

      Verma, Mohit S.; Chen, Paul Z.; Jones, Lyndon W.; Gu, Frank X. (Elsevier, 2015-09)
      Conventional lock-and-key biosensors often only detect a single pathogen because they incorporate biomolecules with high specificity. “Chemical nose” biosensors are overcoming this limitation and identifying multiple ...
    • Corneal sensitivity after ocular surgery 

      Lum, Edward; Murphy, Paul J.; Corbett, Melanie (Wolters Kluwer, 2019-07-01)
      The cornea is densely innervated with free nerve endings to provide a high level of sensitivity to foreign bodies or noxious substances. They also provide trophic support to the tissues of the cornea and facilitate their ...
    • Corneal Swelling with Cosmetic etafilcon A Lenses versus No Lens Wear: 

      Moezzi, Amir Mahmoud; Varikooty, Jalaiah; Schulze, Marc; Ngo, William; Lorenz, Kathrine O.; Boree, Danielle; Jones, Lyndon W. (Wolters & Kluwer, 2016-06)
      Purpose: To determine if the use of pigments or adding polyvinyl pyrrolidone during the fabrication of 1-DAY ACUVUE DEFINE (AD) brand contact lenses impacts open-eye corneal swelling compared with no lens wear (NLW). ...
    • The correction of static and dynamic aniseikonia with spectacles and contact lenses 

      McNeill, Suzanne; Bobier, William (Wiley, 2017-02-16)
      We describe a case of where significant anisometropic astigmatism was accompanied with considerable asthenopic symptoms. Symptoms were not alleviated by the prescribing of a partial spectacle correction. Subsequent treatment ...
    • Correlation of visually evoked intrinsic optical signals and electroretinograms recorded from chicken retina with a combined functional optical coherence tomography and electroretinography system 

      Akhlagh Moayed, Alireza; Hariri, Sepideh; Choh, Vivian Cheng-Pei; Bizheva, Kostadinka (Society of Photo Optical Instrumentation Engineers, 2012-02-08)
      Visually evoked fast intrinsic optical signals (IOSs) were recorded for the first time in vivo from all layers of healthy chicken retina by using a combined functional optical coherence tomography (fOCT) and electroretinography ...
    • Deep Generative Modeling Based Retinal Image Analysis 

      Sengupta, Sourya (University of Waterloo, 2020-06-16)
      In the recent past, deep learning algorithms have been widely used in retinal image analysis (fundus and OCT) to perform tasks like segmentation and classification. But to build robust and highly efficient deep learning ...
    • Developing algorithms for the analysis of retinal Optical Coherence Tomography images 

      Gholami, Peyman (University of Waterloo, 2018-09-04)
      Vision loss, with a prevalence loss greater than 42 million in the United States is one of the major challenges of today's health-care industry and medical science. Early detection of different retinal-related diseases ...
    • Development and application of a new Attended Field of View (AFOV) test 

      Hernandez-Luna, Clara Patricia (University of Waterloo, 2010-05-21)
      Purpose: An important challenge for eye care practitioners is meeting the needs of an ever-increasing elderly population. Standard vision tests are inadequate for determining performance in real life situations. One test ...
    • Development of a new grading scale for tear ferning 

      Masmali, Ali M.; Murphy, Paul J.; Purslow, Christine (Elsevier, 2013-10-25)
      Purpose: This paper reports on the development of a new tear ferning (TF) subjective grading scale, and compares it with the Rolando scale. Method: TF patterns obtained from tear film samples collected from normal and dry ...
    • The Development of an Antibody-Drug Conjugate to Specifically Target and Soften the Crystalline Lens in vivo 

      Won, Gah-Jone (University of Waterloo, 2017-04-04)
      Helmholtz’s classical theory of accommodation states that, within the eye, contraction of the annular ciliary muscle releases the passive tension of zonules that hold the lens in a flattened state. As a result, the surface ...
    • Development of an Arabic Continuous Text Near Acuity Chart 

      Alabdulkader, Balsam (University of Waterloo, 2017-04-24)
      Purpose: Near visual acuity is an essential measurement during an oculo-visual assessment. Continuous text near visual acuity charts measure reading acuity and other aspects of reading performance. Arabic is ranked as the ...
    • Development of an in vitro eye model to better represent in vivo physiological conditions 

      Chan, Vivian (University of Waterloo, 2021-06-23)
      Purpose The purpose of this thesis was to optimize a novel in vitro blink model, the OcuBlink, to best mimic the physiological characteristics of the human eye. By improving this in vitro model, the results from in vitro ...
    • Development of an In Vitro Ocular Platform to Test Contact Lenses 

      Phan, Chau-Minh; Walther, Hendrik; Gao, Huayi; Rossy, Jordan; Subbaraman, Lakshman N.; Jones, Lyndon W. (Journal of Visualized Experiments, 2016-06-04)
      Currently, in vitro evaluations of contact lenses (CLs) for drug delivery are typically performed in large volume vials,1-6 which fail to mimic physiological tear volumes.7 The traditional model also lacks the natural tear ...

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