Now showing items 111-130 of 249

    • Historical overview of imaging the meibomian glands 

      Ngo, William; Srinivasan, Sruthi; Jones, Lyndon W. (Elsevier, 2013-01)
      Growing knowledge of the role of the meibomian glands in dry eye disease and contact lens discomfort has resulted in a surge of interest in visualizing these glands within the eyelids. This manuscript provides an overview ...
    • Image Restoration Methods for Retinal Images: Denoising and Interpolation 

      Thapa, Damber (University of Waterloo, 2015-04-27)
      Retinal imaging provides an opportunity to detect pathological and natural age-related physiological changes in the interior of the eye. Diagnosis of retinal abnormality requires an image that is sharp, clear and free of ...
    • Immobilization of Gold Nanoparticles for Colourimetric and Ratiometric Refractive Index Sensing 

      Pollit, Lori (University of Waterloo, 2019-12-12)
      The development of refractive index sensors is an expanding field of research, with applications in fields including medical diagnostics, food safety and public health. Nanotechnology has become widely implemented in various ...
    • Impact of contact lens wear on epithelial alterations in keratoconus 

      Sorbara, Luigina; Lopez, Jose Carlos Lopez; Gorbet, Maud; Bizheva, Kostadinka; Lamarca, Jose Mateu; Pastor, José-Carlos; López, Miguel José Maldonado; Hileeto, Denise (Elsevier, 2021-03)
      Purpose The purpose of this study was to characterize the central epithelial thickness (CET) of penetrating keratoplasty corneal specimens obtained from patients with keratoconus (KC) and correlate the histological patterns ...
    • Impact of in vitro Tear Film Composition on Lysozyme Deposition and Denaturation 

      Ng, Alan (University of Waterloo, 2012-08-31)
      Purpose To study the impact of lactoferrin and lipids on the kinetic deposition and denaturation of lysozyme on contact lens materials. Methods The contact lenses investigated in this thesis included two silicone ...
    • Impact of Light Scatter on the Assessment of Retinal Arteriolar Hemodynamics 

      Azizi, Behrooz (University of Waterloo, 2010-04-29)
      Introduction and Purpose: Vascular pathologies play an important role in the etiology and progression of number of ocular diseases. Many instruments are developed to monitor retinal hemodynamics, including the Canon Laser ...
    • Impact of Wavefront-Guided Laser in situ Keratomileusis on Monochromatic Higher Order Aberrations and Vision 

      Keir, Nancy (University of Waterloo, 2008-07-04)
      Wavefront-guided (WFG) laser in situ keratomileusis (LASIK) differs from conventional surgery by applying a refined algorithm for tissue removal, based on information from preoperative wavefront aberration data. Since the ...
    • Impression Cytology of the Lid Wiper Area 

      Jones, Lyndon W.; Subbaraman, Lakshman N.; Muntz, Alex; van Doorn, Kevin (Journal of Visualized Experiments, 2016-09-08)
      Few reports on the cellular anatomy of the lid wiper (LW) area of the inner eyelid exist and only one report makes use of cytological methods. The optimization of a method of collecting, staining and imaging cells from the ...
    • In vitro analysis of wettability and physical properties of blister pack solutions of hydrogel contact lenses 

      Menzies, Kara Laura (University of Waterloo, 2010-04-30)
      Contact lens success is primarily driven by comfort of the lens in eye. Over the years, many modifications have been made to the lens surface and bulk material to improve comfort of the lens, however 50% of contact lens ...
    • In vitro and ex vivo wettability of hydrogel contact lenses 

      Rogers, Ronan (University of Waterloo, 2006)
      The wettability of contact lenses has become an area of intense research, with the belief that the more "hydrophilic" or wettable the lens surface is, the more comfortable the lens may be, as the posterior surface of the ...
    • In Vitro and In Vivo Evaluation of Novel Ciprofloxacin-Releasing Silicone Hydrogel Contact Lenses 

      Hui, Alex; Willcox, Mark D. P.; Jones, Lyndon W. (Association for Research in Vision and Ophthalmology, 2014-08-08)
      Purpose.: The purpose of this study was to evaluate ciprofloxacin-releasing silicone hydrogel contact lens materials in vitro and in vivo for the treatment of microbial keratitis. Methods.: Model silicone hydrogel contact ...
    • In Vitro Competitive Binding of Major Tear Proteins to Contact Lenses 

      Jadi, Salsabeel (University of Waterloo, 2013-09-27)
      Purpose To study the impact of incubation solution complexity on protein deposition to silicone hydrogel (SH) contact lenses and the effect of contact lens cleaning solutions on protein activity and removal. Methods The ...
    • In Vitro Release of Inflammatory Cytokines from Contact Lens Materials 

      Nagaarudkumaran, Nijani (University of Waterloo, 2020-12-22)
      The upregulation of inflammatory mediators in the tear film during contact lens wear indicates that lens wear may induce an inflammatory response on the ocular surface. Previous research has investigated the relationship ...
    • In vitro ultraviolet–induced damage in human corneal, lens, and retinal pigment epithelial cells 

      Youn, Hyun-Yi; McCanna, David J.; Sivak, Jacob G.; Jones, Lyndon W. (Molecular Vision, 2011-01-21)
      Purpose: The purpose was to develop suitable in vitro methods to detect ocular epithelial cell damage when exposed to UV radiation, in an effort to evaluate UV-absorbing ophthalmic biomaterials.Methods: Human corneal ...
    • In Vivo Imaging of Corneal Conditions using Optical Coherence Tomography 

      Haque, Sameena (University of Waterloo, 2006)
      Purposes: To use optical coherence tomography (OCT) to image and quantify the effect of various corneal conditions, in terms of corneal, stromal and epithelial thickness, and light backscatter. To assess the changes ...
    • Influence of Conjunctival Folds on Calculated Tear Meniscus Volume Along the Lower Eyelid 

      Bandlitz, Stefan; Purslow, Christine; Murphy, Paul J.; Pult, Heiko (Elsevier, 2016-05-03)
      Purpose: In calculating tear meniscus volume (TMV), tear meniscus height (TMH), radius (TMR) and cross-sectional area (TMA) are usually measured at the center of the lower lid margin, but lid-parallel conjunctival folds ...
    • Infrared Imaging of Meibomian Glands and Evaluation of the Lipid Layer in Sjogren's Syndrome Patients and Nondry Eye Controls 

      Menzies, K. L.; Srinivasan, Sruthi; Prokopich, C. L.; Jones, Lyndon W. (Association for Research in Vision and Ophthalmology, 2015-05-02)
      Purpose.: The purpose of this study was to evaluate meibomian gland dropout and lipid layer thickness (LLT) in patients with and without Sjögren's syndrome dry eye (SS). Methods.: We recruited 11 participants with SS ...
    • Inhibition of Defocus-Induced Myopia in Chickens 

      Woods, Jill; Guthrie, Sarah E.; Keir, Nancy; Dillehay, Sally; Tyson, Mark; Griffin, Richard; Choh, Vivian Cheng-Pei; Fonn, Desmond; Jones, Lyndon W.; Irving, Elizabeth (Association for Research in Vision and Ophthalmology, 2013-04-12)
      Purpose.: To determine the effect of wearing a lens with a unique peripheral optical design on the development and progression of defocus-induced myopia in newly hatched chickens.Methods.: Eighty-five newly hatched chickens ...
    • Insights to Using Contact Lenses for Drug Delivery 

      Phan, Chau-Minh; Walther, Hendrik; Gao, Huayi; Rossy, Jordan; Subbaraman, Lakshman N.; Jones, Lyndon W. (Omics International, 2013)
      There has been considerable interest in the potential application of contact lenses for ocular drug delivery. This short communication provides an overview of the challenges faced by delivering drugs using contact lenses, ...
    • Interaction of Tear Inflammatory Markers with Contact Lens Materials 

      Mirzapour, Parisa (University of Waterloo, 2020-01-28)
      Biomaterials are natural or synthetic materials that come into contact with biological tissue. Contact lenses are the most commonly used biomaterials, being worn by an estimated 140 million people worldwide. While contact ...


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