Browsing Optometry and Vision Science by Title
Now showing items 60-79 of 244
-
Deep Generative Modeling Based Retinal Image Analysis
(University of Waterloo, 2020-06-16)In the recent past, deep learning algorithms have been widely used in retinal image analysis (fundus and OCT) to perform tasks like segmentation and classification. But to build robust and highly efficient deep learning ... -
Developing algorithms for the analysis of retinal Optical Coherence Tomography images
(University of Waterloo, 2018-09-04)Vision loss, with a prevalence loss greater than 42 million in the United States is one of the major challenges of today's health-care industry and medical science. Early detection of different retinal-related diseases ... -
Development and application of a new Attended Field of View (AFOV) test
(University of Waterloo, 2010-05-21)Purpose: An important challenge for eye care practitioners is meeting the needs of an ever-increasing elderly population. Standard vision tests are inadequate for determining performance in real life situations. One test ... -
Development of a new grading scale for tear ferning
(Elsevier, 2013-10-25)Purpose: This paper reports on the development of a new tear ferning (TF) subjective grading scale, and compares it with the Rolando scale. Method: TF patterns obtained from tear film samples collected from normal and dry ... -
The Development of an Antibody-Drug Conjugate to Specifically Target and Soften the Crystalline Lens in vivo
(University of Waterloo, 2017-04-04)Helmholtz’s classical theory of accommodation states that, within the eye, contraction of the annular ciliary muscle releases the passive tension of zonules that hold the lens in a flattened state. As a result, the surface ... -
Development of an Arabic Continuous Text Near Acuity Chart
(University of Waterloo, 2017-04-24)Purpose: Near visual acuity is an essential measurement during an oculo-visual assessment. Continuous text near visual acuity charts measure reading acuity and other aspects of reading performance. Arabic is ranked as the ... -
Development of an in vitro eye model to better represent in vivo physiological conditions
(University of Waterloo, 2021-06-23)Purpose The purpose of this thesis was to optimize a novel in vitro blink model, the OcuBlink, to best mimic the physiological characteristics of the human eye. By improving this in vitro model, the results from in vitro ... -
Development of an In Vitro Ocular Platform to Test Contact Lenses
(Journal of Visualized Experiments, 2016-06-04)Currently, in vitro evaluations of contact lenses (CLs) for drug delivery are typically performed in large volume vials,1-6 which fail to mimic physiological tear volumes.7 The traditional model also lacks the natural tear ... -
Development of Form Visual Acuity in Infants Measured by Schematic Faces
(University of Waterloo, 2018-10-05)Purpose The purpose of this thesis was 1) to develop a test of visual acuity (VA) to measure recognition (form) acuity at a younger age than is currently clinically possible (3 years). Currently, it is only possible to ... -
Development of Novel Techniques for Measuring Bulbar Conjunctival Red Blood Cell Velocity, Oximetry and Redness
(University of Waterloo, 2009-04-29)Introduction The ocular surface provides a unique opportunity to study hemodynamics since the vessels can be visualized directly, without treatment and non-invasively. The availability of instruments to measure various ... -
Development of Sensitive In Vitro Assays to Assess the Ocular Toxicity Potential of Chemicals and Ophthalmic Products
(University of Waterloo, 2009-04-27)The utilization of in vitro tests with a tiered testing strategy for detection of mild ocular irritants can reduce the use of animals for testing, provide mechanistic data on toxic effects, and reduce the uncertainty ... -
Development of sports-specific classification for Paralympic skiers with visual impairment
(University of Waterloo, 2020-05-28)Introduction: The Paralympic Games are not only a platform for athletes with disabilities to achieve their dreams, but the Games also play a major role in changing societal attitudes towards people with disabilities and ... -
Development of visual acuity and contrast sensitivity in children
(University of Waterloo, 2011-07-11)Purpose: There is little agreement on the age at which visual acuity (VA) and contrast sensitivity (CS) become adult-like. The ultimate purpose of this thesis was to determine whether VA and CS are adult-like at the age ... -
Diabetic retinopathy grading with respect to the segmented lesions
(University of Waterloo, 2022-05-19)One of the leading causes of irreversible vision loss is Diabetic Retinopathy (DR). The International Clinical Diabetic Retinopathy scale (ICDRS) provides grading criteria for DR. Deep Convolutional Neural Networks (DCNNs) ... -
A differential role for the posterior cerebellum in the adaptive control of convergence eye movements
(Elsevier, 2020-02)Introduction The vergence oculomotor system possesses two robust adaptive mechanisms; a fast “dynamic” and a slow “tonic” system that are both vital for single, clear and comfortable binocular vision. The neural substrates ... -
Doppler SD-OCT Blood Flow Analysis and Extraneous Operator Influences
(University of Waterloo, 2014-01-30)Purpose: The RTVue-100 is a new instrument for measuring retinal blood flow (RBF), but image quality needs to be optimized in order for valid blood flow results. The primary aim of this thesis was to assess the presence ... -
Dose-effect autonomic responses to ocular surface stimulation
(University of Waterloo, 2018-04-26)Introduction: The ocular surface is one of the most densely innervated superficial tissues of the human body supplied extensively by autonomic and sensory nerve fibres. Studies have shown that ocular surface sensory neurons ... -
Effect of aging on measures of visual attention using dual tasks and visual search
(University of Waterloo, 2010-01-19)In Canada, as baby boomers age, there will be an increase in the percentage of seniors within the general population (Statistics Canada, 2006). Seniors often have difficulty in performing certain everyday tasks and have ... -
Effect of ambient humidity on the Cochet-Bonnet aesthesiometer
(Springer Nature, 2018-06-19)Purpose: The Cochet–Bonnet (COBO) aesthesiometer is the current standard in corneal sensitivity assessment. This study investigates the influence of ambient room humidity levels on the stimulus force exerted by the ... -
Effect of heterophoria type and myopia on accommodative and vergence responses during sustained near activity in children
(Elsevier, 2012-03-15)The influence of phoria-type and myopia on changes to vergence and accommodation during prolonged near-task was examined in 53 children. Participants were classified into phoria and refractive categories based on near ...