Browsing Science (Faculty of) by Subject "Xenopus"
Now showing items 1-9 of 9
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Celastrol, a proteasome inhibitor, can induce the expression of heat shock protein genes in Xenopus cultured cells
(University of Waterloo, 2010-01-25)Heat shock proteins (HSPs) are stress-inducible and evolutionarily conserved molecular chaperones that are involved in protein binding and translocation. As molecular chaperones, HSPs bind to denatured proteins, inhibit ... -
Characterization on PAR-3 in early Xenopus laevis development
(University of Waterloo, 2013-01-24)Polarized cell movements are essential to the cell rearrangements that occur during morphogenesis. In Xenopus, cell polarity is reflected in the directional cell intercalations that drive the morphogenetic movements ... -
Effect of hemin and baicalein on heme oxygenase-1 accumulation and function in Xenopus laevis cultured cells
(University of Waterloo, 2018-04-26)Heme oxygenase-1 (HO-1) is a stress-inducible enzyme that catalyzes the rate-limiting step in the hemin degradation pathway. Studies in mammalian systems determined that HO-1 promoted cell survival by reducing oxidative ... -
Examination of the effect of the natural plant extract, withaferin A, on heat shock protein gene expression in Xenopus laevis A6 cells
(University of Waterloo, 2010-09-03)In eukaryotes, the ubiquitin-proteasome system (UPS) degrades most cellular protein. Inhibition of the UPS has been associated with different disease states and can affect various intracellular processes including the ... -
Examination of the expression of the heat shock protein gene, hsp110, in Xenopus laevis cultured cells and embryos
(University of Waterloo, 2008-01-16)Prokaryotic and eukaryotic organisms respond to various stressors with the production of heat shock proteins (HSPs). HSP110 is a large molecular mass HSP that is constitutively expressed in most adult mammalian tissues. ... -
Measurement of Tensile Forces in Xenopus laevis Neural Tissue
(University of Waterloo, 2010-01-22)Neurulation is critical for the proper development of the central nervous system during embryogenesis. This process requires coordinated morphogenetic movements driven by localized cell movements. The key morphogenetic ... -
Regulation of Integrin Function by XGIPC
(University of Waterloo, 2008-08-25)Integrins are a large family of transmembrane cell adhesion receptors that are found on the surface of eukaryotic cells. Integrins act predominantly as cell surface receptors for extracellular matrix (ECM) proteins, but ... -
Role of PINCH during early Xenopus embryogenesis
(University of Waterloo, 2012-08-31)In the Xenopus embryo, cell rearrangements during early development require the dynamic modulation of adhesion. Cells primarily use the integrin family of transmembrane receptors for attachment to and interpretation of the ... -
β‐Parvin Mediates Novel Integrin Signaling Pathways During Early Xenopus laevis Development.
(University of Waterloo, 2019-01-24)Crosstalk between cell adhesion molecules is critical for the cell rearrangements that occur during early Xenopus laevis development. Cells primarily use integrin receptors to adhere to and interpret the extracellular ...