Browsing Science (Faculty of) by Subject "SPME"
Now showing items 1-20 of 21
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Application of matrix compatible solid phase microextraction (SPME) coatings for the analysis in complex food matrices
(University of Waterloo, 2020-01-06)In recent years, studies regarding food analysis have increased due to the globalization of food trade as well as concerns about the safety and traceability of food commodities. In this regard, the field of food analysis ... -
Application of Solid Phase Microextraction for Lipid Analysis and Lipidomics
(University of Waterloo, 2016-01-29)Although the latest advancements in lipid analysis technology provide an excellent opportunity for the comprehensive study of lipidome, fulfilling the analytical requirements at the desired quality is still a major ... -
Cold fiber solid phase microextraction in solid sample analysis
(University of Waterloo, 2013-05-03)The cold fiber solid phase microextraction (SPME) system was improved by minimizing the coating temperature fluctuation range, and the performance of the system was evaluated by investigating the extraction of PAHs from ... -
Determination of Geosmin and 2-Methylisoborneol in Fish using In-vivo Solid Phase Microextraction
(University of Waterloo, 2012-08-31)The presence of off-flavor compounds in fish represents one of the significant economic problems encountered in aquaculture. These off-flavor compounds are due to the absorption of substances produced by microorganisms. ... -
Development and Application of Solid-Phase Microextraction Probe Electrospray Ionization
(University of Waterloo, 2020-12-21)Ambient ionization mass spectrometry (AIMS) is a category of mass spectrometry (MS) techniques originally characterized as using ambient ionization sources to analyze samples with little to no sample preparation and no ... -
Development and application of SPME technologies for the rapid sampling and analysis of anthropogenic compounds in the environment
(University of Waterloo, 2017-04-27)Due to the wide spread use of pharmaceuticals in both human and animal populations, the contamination of surface waters resulting from the outflow of waste water treatment facilities is of growing concern. Conventional ... -
Development and optimization of coated blade spray - mass spectrometry for bioanalytical and clinical applications
(University of Waterloo, 2018-08-23)Bioanalysis is a sub-discipline of analytical chemistry that focuses on the identification and quantification of small and large molecules (e.g. metabolites and proteins) present in biological sample matrices (e.g. blood, ... -
Development of Field Portable Solid Phase Microextraction Samplers for Performing On-site Environmental Analysis
(University of Waterloo, 2018-04-30)Since being introduced in 1989 solid phase microextraction (SPME) techniques have continually evolved from within the analytical chemistry community due in large part to their clean, portable and easy to handle design. It ... -
Development of novel spme coatings and high-throughput automation of sample preparation for pharmaceutical and clinical samples
(University of Waterloo, 2009-12-23)Increasing the efficiency of the methods used through the development and trial of novel pharmaceutical compounds is an important step to reduce the time required to develop new medical treatments. Before a drug can be ... -
The effect of hematocrit on solid-phase microextraction
(Elsevier, 2018-02-25)Solid-phase microextraction (SPME) is an approach to sample preparation that has demonstrated its appropriateness for isolating/enriching analytes present in complex biofluids with minimum sample pre-treatment. Several ... -
Equilibrium ex vivo calibration of homogenized tissue for in vivo SPME quantitation of doxorubicin in lung tissue
(Elsevier, 2018-06-01)The fast and sensitive determination of concentrations of anticancer drugs in specific organs can improve the efficacy of chemotherapy and minimize its adverse effects. In this paper, ex vivo solid-phase microextraction ... -
A facile and fully automated on-fiber derivatization protocol for direct analysis of short-chain aliphatic amines using a matrix compatible solid-phase microextraction coating
(Elsevier, 2017-07-29)Solid-phase microextraction (SPME) analysis of short-chain aliphatic amines (C-3-C-6) in aqueous solutions was investigated using pentafluorobenzaldehyde (PFBAY) as on-fiber derivatization reagent. A standard gas generating ... -
Fundamentals of SPME extraction of tissue and plasma: experimental and in-silico approaches
(University of Waterloo, 2021-12-15)Over the last three decades, solid-phase microextraction (SPME) has continuously evolved and received recognition as a useful tool in various scientific fields. Notable applications have been published including environmental ... -
Immunoaffinity Solid Phase Microextraction
(University of Waterloo, 2007-12-18)Biological fluids are commonly analyzed in clinical and forensic studies for drug concentration measurements. Conventional quantification procedures are always associated with lengthy sample pretreatment steps to eliminate ... -
In Vivo Detection of Trace Organic Contaminants in Fish Using Solid Phase Microextraction
(University of Waterloo, 2010-10-21)The feasibility of using solid phase micro-extraction (SPME) as an in vivo sampling tool for analysis of trace environmental contaminants in fish exposed to municipal wastewater effluents (MWWEs) was validated using ... -
Needle Trap Device and Solid Phase Microextraction Combined with Portable GC-MS for On-Site Applications
(University of Waterloo, 2011-06-21)Needle trap device (NTD) is a technique that is useful for a wide variety of applications involving the sample preparation of compounds with a wide range of chemico-physico properties, and varying volatilities. A newly ... -
On-Site Sampling and Determination of Aliphatic Amines in Industrial Waste Water using SPME
(University of Waterloo, 2012-01-06)In any oil production company, one of the problems that is faced on a daily basis and which sometimes hinders the operation is corrosion. In the presence of dissolved oxygen in the water inside any vessel, tank, or pipeline, ... -
Optimization of SPME coating characteristics for metabolomics and targeted analysis with LC/MS
(University of Waterloo, 2015-09-23)Metabolomics data provides complementary information to proteomics, genomics, and transcriptomics, in addition to enabling the tracking of the dynamic reactions in living systems. Metabolomics is widely used in various ... -
Solid Phase Microextraction as a Sample Preparation Tool for Targeted and Untargeted Analysis of Biological Matrices
(University of Waterloo, 2017-09-27)Successful determination of small molecules in complex biological systems requires implementation of robust analytical methodologies able to provide reliable information in a cost-effective and efficient manner. Solid phase ... -
Strategies for the Direct Coupling of Solid Phase Microextraction to Mass Spectrometry
(University of Waterloo, 2017-09-27)In recent years, advances in direct sample to mass spectrometry (MS) techniques have allowed for the application of these methods towards quantitative analysis in complex matrices such as biofluids and tissue. However, the ...