Browsing Waterloo Research by Subject "DNA"
Now showing items 41-60 of 68
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Instantaneous Attachment of an Ultrahigh Density of Nonthiolated DNA to Gold Nanoparticles and Its Applications
(American Chemical Society, 2012-12-11)The last 16 years have witnessed the landmark development of polyvalent thiolated DNA-functionalized gold nanoparticles (AuNP's) possessing striking properties within the emerging field of nanobiotechnology. Many novel ... -
Iron oxide nanozyme catalyzed synthesis of fluorescent polydopamine for light-up Zn2+ detection
(Royal Society of Chemistry, 2016-07-29)Fluorescent polydopamine (FPD) is an interesting material with excellent biocompatibility. However, its preparation is currently a lengthy and potentially dangerous process. We herein employ magnetic iron oxide (Fe3O4) ... -
Light-Activated Metal-Coordinated Supramolecular Complexes with Charge-Directed Self-Assembly
(American Chemical Society, 2013-02-21)Metal-coordinated materials are attractive for many applications including catalysis, sensing, and controlled release. Adenine and its derivatives have been widely used to generate many coordination complexes, polymers, ... -
Magnetic Iron Oxide Nanoparticle Seeded Growth of Nucleotide Coordinated Polymers
(American Chemical Society, 2016-06-22)The introduction of functional molecules to the surface of magnetic iron oxide nanoparticles (NPs) is of critical importance. Most previously reported methods were focused on surface ligand attachment either by physisorption ... -
Mechanisms of DNA Sensing on Graphene Oxide
(American Chemical Society, 2013-08-20)Adsorption of a fluorophore-labeled DNA probe by graphene oxide (GO) produces a sensor that gives fluorescence enhancement in the presence of its complementary DNA (cDNA). While many important analytical applications have ... -
Metal-Induced Specific and Nonspecific Oligonucleotide Folding Studied by FRET and Related Biophysical and Bioanalytical Implications
(Wiley, 2012-01-13)Metal induced nucleic acid folding has been extensively studied with ribozymes, DNAzymes, tRNA and riboswitches. These RNA/DNA molecules usually have a high content of double-stranded regions to support a rigid scaffold. ... -
Molecular Beacon Lighting up on Graphene Oxide
(American Chemical Society, 2012-05-01)A molecular beacon (MB) is comprised of a fluorophore and a quencher linked by a DNA hairpin. MBs have been widely used for homogeneous DNA detection. In addition to molecular quenchers, many nanomaterials such as graphene ... -
Nucleotide coordination with 14 lanthanides studied by isothermal titration calorimetry
(Elsevier, 2017-06-09)With their hydrolytic, optical and magnetic properties, lanthanide ions (Ln3+) are versatile probes for nucleic acids. In addition, nucleotide-coordinated Ln3+ ions form useful nanoparticles. However, the thermodynamic ... -
Oligonucleotide-functionalized hydrogels as stimuli responsive materials and biosensors
(Royal Society of Chemistry, 2011-08-07)Hydrogels are crosslinked hydrophilic polymers that undergo swelling in water. The gel volume is affected by many environmental parameters including temperature, pH, ionic strength, and solvent composition. Therefore, these ... -
Platinated DNA oligonucleotides: new probes forming ultrastable conjugates with graphene oxide
(Royal Society of Chemistry, 2014-06-21)Metal containing polymers have expanded the property of polymers by involving covalently associated metal complexes. DNA is a special block copolymer. While metal ions are known to influence DNA, little is explored on its ... -
A platinum shell for ultraslow ligand exchange: unmodified DNA adsorbing more stably on platinum than thiol and dithiol on gold
(Royal Society of Chemistry, 2015-08-04)Due to the ultraslow ligand exchange rate on Pt, non-thiolated DNA is adsorbed on platinum nanoparticles (PtNPs) more stably than thiolated and even dithiolated DNA on AuNPs. Adsorption kinetics, capacity and stability are ... -
Polarity Control for Nonthiolated DNA Adsorption onto Gold Nanoparticles
(American Chemical Society, 2013-05-21)Gold nanoparticles (AuNPs) functionalized with thiolated DNA have enabled many studies in nanoscience. The strong thiol/gold affinity and the nanoscale curvature of AuNPs allow the attached DNA to adapt an upright conformation ... -
Polymeric rapid prototyping for inexpensive and portable medical diagnostics
(Society of Photo-optical Instrumentation Engineers, 2012-10-24)The advent of inexpensive CO2 laser systems has led to a wide range of demonstrations of microfabricated lab on chip systems built of acrylic. However, there has been little application of these systems to building ... -
Programmable Assembly of DNA-Functionalized Liposomes by DNA
(American Chemical Society, 2011-02-22)Bionanotechnology involves the use of biomolecules to control both the structure and property of nanomaterials. One of the most studied examples is DNA-directed assembly of inorganic nanoparticles such as gold nanoparticles ... -
Protection and Promotion of UV Radiation-Induced Liposome Leakage via DNA-Directed Assembly with Gold Nanoparticles
(Wiley, 2011-07-26)DNA-functionalized gold nanoparticles and liposomes are assembled by a linker DNA. The gold nanoparticles can either protect the liposome from UV radiation induced leakage or can promote the leakage, depending on the DNA ... -
Rationally Designed Nucleobase and Nucleotide Coordinated Nanoparticles for Selective DNA Adsorption and Detection
(American Chemical Society, 2013-12-17)Nanomaterials for DNA adsorption are useful for sequence-specific DNA detection. Current materials for DNA adsorption employ electrostatic attraction, hydrophobic interaction, or π–π stacking, none of which can achieve ... -
Regenerable DNA-Functionalized Hydrogels for Ultrasensitive, Instrument-Free Mercury(II) Detection and Removal in Water
(American Chemical Society, 2010-09-15)Mercury is a highly toxic environmental pollutant with bioaccumulative properties. Therefore, new materials are required to not only detect but also effectively remove mercury from environmental sources such as water. We ... -
The Self-Assembly of Particles with Isotropic Interactions
(IOP publishing, 2013-07-03)A generic field-theoretic model for the self-assembly of particles with isotropic interactions, motivated by ideas in DNA-mediated colloidal assembly, is presented. A simplest possible system of colloids in explicit ... -
The self-assembly of particles with isotropic interactions: Using DNA coated colloids to create designer nanomaterials
(AIP publishing, 2014-04-03)Self-consistent field theory equations are presented that are suitable for use as a coarse-grained model for DNA coated colloids, polymer-grafted nanoparticles and other systems with approximately isotropic interactions. ... -
Stimuli-responsive releasing of gold nanoparticles and liposomes from aptamer-functionalized hydrogels
(Institute of Physics, 2011-11-21)Controlled release of therapeutic agents is important for improving drug efficacy and reducing toxicity. Recently, hydrogels have been used for controlled release applications. While the majority of the previous work focused ...