Browsing Waterloo Research by Author "Pawliszyn, Janusz"
Now showing items 41-55 of 55
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Numerical Modeling of Solid-Phase Microextraction: Binding Matrix Effect on Equilibrium Time
Alam, Md. Nazmul; Ricardez-Sandoval, Luis; Pawliszyn, Janusz (American Chemical Society, 2015-10-06)Solid-phase microextraction (SPME) is a well-known sampling and sample preparation technique used for a wide variety of analytical applications. As there are various complex processes taking place at the time of extraction ... -
Numerical simulation and experimental validation of calibrant-loaded extraction phase standardization approach
Alam, Md. Nazmul; Pawliszyn, Janusz (American Chemical Society, 2016-08-10)We present the kinetics of calibrant release and analyte uptake between the sample and calibrant-loaded extraction phase, CL-EP with a finite-element analysis (FEA) using COMSOL Multiphysics® software package. Effect of ... -
Numerical Simulation and Experimental Validation of Calibrant-Loaded Extraction Phase Standardization Approach
Alam, Md. Nazmul; Pawliszyn, Janusz (American Chemical Society, 2016-09-06)We present the kinetics of calibrant release and analyte uptake between the sample and calibrant-loaded extraction phase, CL-EP, with a finite-element analysis (FEA) using COMSOL Multiphysics software package. Effect of ... -
Open Port Probe Sampling Interface for the Direct Coupling of Biocompatible Solid-Phase Microextraction to Atmospheric Pressure Ionization Mass Spectrometry
Gomez-Rios, German Augusto; Liu, Chang; Tascon, Marcos; Reyes-Garcés, Nathaly; Arnold, Don W.; Covey, Thomas R.; Pawliszyn, Janusz (American Chemical Society, 2017-04-04)In recent years, the direct coupling of solid phase microextraction (SPME) and mass spectrometry (MS) has shown its great potential to improve limits of quantitation, accelerate analysis throughput, and diminish potential ... -
Quantitative analysis of biofluid spots by coated blade spray mass spectrometry, a new approach to rapid screening
Boyaci, Ezel; Gómez-Ríos, Germán Augusto; Pawliszyn, Janusz; Poole, Justen J.; Tascon, Marcos; Reyes-Garcés, Nathaly (Springer Nature, 2017-11-23)This study demonstrates the quantitative capabilities of coated blade spray (CBS) mass spectrometry (MS) for the concomitant analysis of multiple target substances in biofluid spots. In CBS-MS the analytes present in a ... -
Rapid determination of immunosuppressive drug concentrations in whole blood by coated blade spray-tandem mass spectrometry (CBS-MS/MS)
Gómez-Ríos, Germán Augusto; Tascon, Marcos; Reyes-Garcés, Nathaly; Boyaci, Ezel; Poole, Justen J.; Pawliszyn, Janusz (Elsevier, 2018-01-25)Coated Blade Spray (CBS) is a technology that efficiently integrates sample preparation and direct coupling to mass spectrometry (MS) on a single device. In this article, we present CBS-tandem mass spectrometry (CBS-MS/MS) ... -
Review of geometries and coating materials in solid phase microextraction: Opportunities, limitations, and future perspectives
Piri-Moghadam, Hamed; Alam, Md. Nazmul; Pawliszyn, Janusz (Elsevier, 2017-09-01)The development of new support and geometries of solid phase microextraction (SPME), including metal fiber assemblies, coated-tip, and thin film microextraction (TFME) (i.e. self-supported, fabric and blade supported), as ... -
The Saliva Exposome for Monitoring of Individuals’ Health Trajectories
Bessonneau, Vincent; Pawliszyn, Janusz; Rappaport, Stephen M. (Environmental Health Perspectives - United States Federal Government, 2017-07-20)Background: There is increasing evidence that environmental, rather than genetic, factors are the major causes of most chronic diseases. By measuring entire classes of chemicals in archived biospecimens, exposome-wide ... -
Solid Phase Microextraction Devices Prepared on Plastic Support as Potential Single-Use Samplers for Bioanalytical Applications
Reyes-Garcés, Nathaly; Bojko, Barbara; Hein, Dietmar; Pawliszyn, Janusz (American Chemical Society, 2015-09-04)This study presents new thin-film solid phase microextraction (SPME) devices prepared on plastic as potential single-use samplers for bioanalysis. Polybutylene terephthalate (PBT) was selected as a support due to its ... -
Solid Phase Microextraction On-Fiber Derivatization Using a Stable, Portable, and Reusable Pentafluorophenyl Hydrazine Standard Gas Generating Vial
Poole, Justen J.; Grandy, Jonathan J.; Gomez-Rios, German Augusto; Gionfriddo, Emanuela; Pawliszyn, Janusz (American Chemical Society, 2017-07-05)Solid phase microextraction (SPME) on-fiber derivatization methods have facilitated the achievement of lower detection limits and targeted analysis of various substances that exhibit poor chromatographic behavior, thermal ... -
Structure/reaction directed analysis for LC-MS based untargeted analysis
Yu, Miao; Olkowicz, Mariola; Pawliszyn, Janusz (Elsevier, 2019-03-07)In LC-MS based untargeted analysis, data is collected at the peak or ion level, although the investigated biochemistry processes occur at the compound or reaction level. To this end, the presence of redundancy peaks such ... -
A study of thin film solid phase microextraction methods for analysis of fluorinated benzoic acids in seawater
Boyaci, Ezel; Goryński, Krzysztof; Viteri, C. Ricardo; Pawliszyn, Janusz (Elsevier, 2016-03-04)Fluorinated benzoic acids (FBAs) are frequently used as tracers by the oil industry to characterize petroleum reservoirs. The demand for fast, reliable, robust, and sensitive approaches to separate and quantify FBAs in ... -
Time Weighted Average Concentration Monitoring Based on Thin Film Solid Phase Microextraction
Ahmadi, Fardin; Sparham, Chris; Boyaci, Ezel; Pawliszyn, Janusz (American Chemical Society, 2017-04-04)Time weighted average (TWA) passive sampling with thin film solid: phase micro extraction (TF-SPME) and liquid chromatography tandem mass spectrometry (LC-MS/MS) was used for collection, identification, and quantification ... -
Time-course monitoring of in vitro biotransformation reaction via solid-phase microextraction-ambient mass spectrometry approaches
Jaroch, Karol; Pawliszyn, Janusz (Elsevier, 2021-08)The solid-phase microextraction technique quantifies analytes without considerably affecting the sample composition. Herein, a proof-of-concept study was conducted to demonstrate the use of coated probe electrospray ... -
Tissue storage affects lipidome profiling in comparison to in vivo microsampling approach
Roszkowska, Anna; Yu, Miao; Bessonneau, Vincent; Bragg, Leslie M.; Servos, Mark R.; Pawliszyn, Janusz (Springer, 2018-05-03)Low-invasive in vivo solid-phase microextraction (SPME) was used to investigate the lipid profiles of muscle tissue of living fish. Briefly, mixed mode SPME fibers were inserted into the muscle for 20 min extraction, and ...