Browsing Mechanical and Mechatronics Engineering by Subject "Microfluidics"
Now showing items 1-10 of 10
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The Design and Evaluation of a Microfluidic Cell Sorting Chip
(University of Waterloo, 2007-01-12)Many applications for the analysis and processing of biological materials require the enrichment of cell subpopulations. Conventional cell sorting systems are large and expensive with complex equipment that necessitates ... -
Development of Microfluidic Chips for High Performance Electrophoresis Separations in Biochemical Applications
(University of Waterloo, 2013-08-23)Electrophoresis separation corresponds to the motion and separation of dispersed particles under the influence of a constant electric field. In molecular biology, electrophoresis separation plays a major role in identifying, ... -
Droplet Production and Transport in Microfluidic Networks with Pressure Driven Flow Control
(University of Waterloo, 2012-07-24)Droplet based microfluidics is a developing technology with great potential towards improving large scale combinatorial studies that require high throughput and accurate metering of reagents. Each droplet can be thought ... -
Droplet-based Microfluidic Chip Design for High Throughput Screening Applications
(University of Waterloo, 2015-12-11)Droplet-based microfluidics has been considered as a prospective tool for high throughput screening analysis, which is highly demanded in a wide range of areas including but not limited to life science research, drug ... -
Expanding the droplet microfluidic community – towards a modular active platform
(University of Waterloo, 2020-12-15)Microfluidics has progressed tremendously as a field over the last two decades. Various areas of microfluidics developed in fully-fledged domains of their own such as organ-on-a-chip, digital and paper microfluidics. Nevertheless, ... -
Feedback Controls in Droplet Microfluidics
(University of Waterloo, 2016-12-21)The ability to stabilize and move individual droplets would allow scientists to perform micro-scale manipulation, and unlock the advantages of microfluidics. The challenge lies in the fact that droplet displacements are ... -
Injection and Separation Evaluation for Microfluidic Protein and DNA Separation
(University of Waterloo, 2018-09-11)Electrophoresis is the separation of charged particles under an applied electric field and is applied for macromolecules such as DNA, proteins, RNA and peptides through a solvent. It has been one of the most widely used ... -
Microfluidic-Based In-Situ Functionalization for Detection of Proteins in Heterogeneous Immunoassays
(University of Waterloo, 2013-01-17)One the most daunting technical challenges in the realization of biosensors is functionalizing transducing surfaces for the detection of biomolecules. Functionalization is defined as the formation of a bio-compatible ... -
Nano-orifice based Dielectrophoretic Manipulation and Characterization of Nanoparticles and Biological Cells
(University of Waterloo, 2019-08-02)Dielectrophoresis (DEP) is the motion of a dielectric particle in an aqueous solution due to the polarization effects in a non-uniform electric field. Due to its property of label-free, scalable, and capable of generating ... -
A Novel Lab-on-chip System for Counting Particles/Cells Based on Electrokinetically-induced Pressure-driven Flow and Dual-wavelength Fluorescent Detection
(University of Waterloo, 2013-12-10)For the past two decades, flow cytometry has been widely used as a powerful analysis tool for the diagnosis of many diseases due to its ability to count, characterize and sort cells. However, conventional flow cytometers ...