Browsing Waterloo Institute for Nanotechnology by Title
Now showing items 180-193 of 193
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Synergistic pH effect for reversible shuttling aptamer-based biosensors between graphene oxide and target molecules
(Royal Society of Chemistry, 2011-06-07)DNA aptamers are known to desorb from graphene oxide (GO) surface in the presence of target molecules. We demonstrate herein that the binding equilibrium can be shifted by simply tuning the solution pH. At lower pH, the ... -
Tandem DNAzymes for mRNA cleavage: choice of enzyme, metal ions and the antisense effect
(Elsevier, 2015-04-01)The concept of DNAzyme-based gene silencing via mRNA cleavage was proposed over twenty years ago. A number of studies regarding intracellular gene silencing have been reported as well. However, questions have been raised ... -
Tandem Phosphorothioate Modifications for DNA Adsorption Strength and Polarity Control on Gold Nanoparticles
(American Chemical Society, 2014-09-10)Unmodified DNA was recently used to functionalize gold nanoparticles via DNA base adsorption. Compared to thiolated DNA, however, the application of unmodified DNA is limited by the lack of sequence generality, adsorption ... -
Targeted nanoparticle binding & detection in petroleum hydrocarbon impacted porous media
(Elsevier, 2019-01-01)Targeted nanoparticle binding has become a core feature of experimental pharmaceutical product design which enables more efficient payload delivery and enhances medical imaging by accumulating nanoparticles in specific ... -
Temperature Response of Aqueous Solutions of Pyrene End-Labeled Poly(N-isopropyl acrylamide)s Probed by Steady-State and Time-Resolved Fluorescence
(Wiley, 2018-02-15)Aqueous solutions of a series of monodisperse poly(N‐isopropylacrylamide)s end‐labeled with n‐butyl‐1‐pyrene at one or both chain ends (Pyn‐PNIPAMs with n = 1 or 2) were studied by turbidimetry, light scattering, and ... -
Testing the Universality of Entropic Segregation at Polymer Surfaces
(2018)This study addresses entropic segregation effects at the surfaces of monodisperse and bidisperse melts. For the monodisperse melts, we focus on the segregation of chain ends to the surface, and for the bidisperse melts, ... -
Toward Fast and Quantitative Modification of Large Gold Nanoparticles by Thiolated DNA: Scaling of Nanoscale Forces, Kinetics, and the Need for Thiol Reduction
(American Chemical Society, 2013-08-01)We have recently reported on the fast and quantitative adsorption of DNA to 13 nm gold nanoparticles (AuNPs) at pH 3. This is in contrast to most traditional methods at neutral pH, where the adsorption is both slow and ... -
Towards understanding of poly-guanine activated fluorescent silver nanoclusters
(Institute of Physics, 2014-03-18)It has been recently reported that the fluorescence of some DNA-templated silver nanoclusters (AgNCs) can be significantly enhanced upon by hybridizing with a partially complementary DNA containing a G-rich overhang near ... -
Tunable covalent organic framework electrochemiluminescence from non-electroluminescent monomers
(Elsevier, 2021-10)It is hard to find new electrochemiluminescence (ECL) luminophores using existing research strategies, especially from ECL non-active monomers. Here, fully conjugated covalent organic frameworks with trithiophene (BTT-COFs) ... -
Two Pb2+-specific DNAzymes with opposite trends in split-site-dependent activity
(Royal Society of Chemistry, 2014-05-04)By splitting the catalytic core of DNAzymes into two halves, two Pb2+-specific DNAzymes retain partial activity, while they show opposite trends of activity as a function of the split site, revealing important nucleotides ... -
Ultrahigh Nanoparticle Stability against Salt, pH, and Solvent with Retained Surface Accessibility via Depletion Stabilization
(American Chemical Society, 2012-06-20)For many applications, it is desirable to stabilize colloids over a wide range of buffer conditions while still retaining surface accessibility for adsorption and reaction. Commonly used charge or steric stabilization ... -
An Ultrasensitive Light-up Cu2+ Biosensor Using a New DNAzyme Cleaving a Phosphorothioate-Modified Substrate
(American Chemical Society, 2017-01-15)Cu2+ is a very important metal ion in biology, environmental science, and industry. Developing biosensors for Cu2+ is a key topic in analytical chemistry. DNAzyme-based sensors are highly attractive:, for their excellent ... -
Visual optical biosensors based on DNA-functionalized polyacrylamide hydrogels
(Elsevier, 2013-12-15)Biosensors are devices that can provide quantitative or semi-quantitative analytical information about target molecules, where molecular recognition is based on biomolecular interactions. In recent years, DNA has emerged ... -
Wetting, adhesion and droplet impact on face masks
(ACS, 2021-02-12)In the present pandemic time, face masks are found to be the most effective strategy against the spread of the virus within the community. As aerosol-based spreading of the virus is considered as the primary mode of ...