Browsing Waterloo Institute for Nanotechnology by Title
Now showing items 162-181 of 193
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Searching for a DNAzyme version of the leadzyme
(Springer, 2015-10-12)The leadzyme refers to a small ribozyme that cleaves a RNA substrate in the presence of Pb2+. In an optimized form, the enzyme strand contains only two unpaired nucleotides. Most RNA-cleaving DNAzymes are much longer. Two ... -
Segregation of chain ends to the surface of a polymer melt: effect of surface profile versus chain discreteness
(Springer, 2016)Silberberg has argued that the surface of a polymer melt behaves like a reflecting boundary on the random-walk statistics of the polymers. Although this is approximately true, independent studies have shown that violations ... -
A Selective Na+ Aptamer Dissected by Sensitized Tb3+ Luminescence
(Wiley, 2016-08-17)A previous study of two RNA-cleaving DNAzymes, NaA43 and Ce13d, revealed the possibility of a common Na+ aptamer motif. Because Na+ binding to DNA is a fundamental biochemical problem, the interaction between Ce13d and Na+ ... -
Self-Assembly of Amphiphilic Nanoparticle-Coil “Tadpole” Macromolecules
(American Chemical Society, 2004)None. -
Self-Assembly of Amphiphilic Nanoparticle-Coil “Tadpole” Macromolecules
(American Chemical Society, 2004)There has been considerable fascination with the self-assembling behavior of amphiphilic chainlike molecules that range from short-chain surfactants to high molecular weight block copolymers. The self-assembly of simple ... -
Self-healable and reversible liposome leakage by citrate-capped gold nanoparticles probing initial adsorption/desorption induced lipid phase transition
(Royal Society of Chemistry, 2015-10-14)We herein report that the adsorption/desorption of citrate-capped gold nanoparticles (AuNPs) transiently causes leakage in fluid phase DOPC liposomes, while the liposomes do not leak with AuNPs capped with mercaptopropionic ... -
Self-healing metal coordinated hydrogels using nucleotide ligands
(Royal Society of Chemistry, 2015-10-21)A supramolecular gel formed by coordination of Zn2+ with adenosine monophosphate (AMP) is reported. The adenine base, the monophosphate, and Zn2+ are all important for gel formation. Mechanically disrupted gels can re-form ... -
A self-powered multi-broadcasting wireless sensing system realized with an all-in-one triboelectric nanogenerator
(Elsevier, 2019-08)The ubiquitous sensors at the core network of Internet of Things (IoT) have accelerated the realization of micro/nano systems that necessitate not only the development of self-powered sensors but also requires a reliable ... -
Self-powered on-line ion concentration monitor in water transportation driven by triboelectric nanogenerator
(Elsevier, 2019-08)Ion concentration in water is a key criterion for evaluating water quality. In this work, we developed a self-powered on-line ion concentration monitor in water transportation based on impedance matching effect of triboelectric ... -
Sensing guanine and its derivatives: From molecular recognition to applications
(Elsevier, 2020-11)Guanine plays an indispensable role in building nucleic acids, and its derivatives take part in various cellular functions such as regulating biological reactions and signal transduction. Monitoring the levels of guanine ... -
Sensing Parts-per-Trillion Cd2+, Hg2+ and Pb2+ Collectively and Individually Using Phosphorothioate DNAzymes
(American Chemical Society, 2014-05-22)Cadmium, mercury, and lead are collectively banned by many countries and regions in electronic devices due to their extremely high toxicity. To date, no sensing method can detect them as a group and also individually with ... -
A Silver DNAzyme
(American Chemical Society, 2016-04-05)Silver is a very common heavy metal, and its detection is of significant analytical importance. DNAzymes are DNA-based catalysts; they typically recruit divalent and trivalent metal ions for catalysis. Herein, we report a ... -
Simulated electron affinity tuning in metal-insulator-metal (MIM) diodes
(American Institute of Physics, 2017-04-27)Metal-insulator-metal diodes for rectification applications must exhibit high asymmetry, nonlinearity, and responsivity. Traditional methods of improving these figures of merit have consisted of increasing insulator ... -
Solvent presence and its impact on the lap-shear strength of SDS-decorated graphene hybrid electrically conductive adhesives
(Elsevier, 2017-10-01)The mechanical bonding strength of electrically conductive adhesives (ECAs), as well as the impact of residual solvent on the bonding strength was investigated between a copper clad FR-4 surface and conductive adhesives ... -
Spontaneous Tilting Transition in Liquid-Crystalline Polymer Brushes
(2019)The equilibrium phase behavior of main-chain liquid-crystalline polymer brushes in good solvent is investigated using self-consistent field theory. The calculation assumes semi-dilute brushes, where the grafting density ... -
Stimuli-responsive releasing of gold nanoparticles and liposomes from aptamer-functionalized hydrogels
(Institute of Physics, 2011-11-21)Controlled release of therapeutic agents is important for improving drug efficacy and reducing toxicity. Recently, hydrogels have been used for controlled release applications. While the majority of the previous work focused ... -
Surface Science of DNA Adsorption onto Citrate-Capped Gold Nanoparticles
(American Chemical Society, 2012-02-28)Single-stranded DNA can be adsorbed by citrate capped gold nanoparticles (AuNPs), resulting in increased AuNP stability, which forms the basis of a number of biochemical and analytical applications, but the fundamental ... -
Surfactant-Structure Dependent Interactions with Modified Starch Nanoparticles Probed by Fluorescence Spectroscopy
(American Chemical Society, 2019-02-05)The interactions between the surfactants sodium dodecyl sulfate (SDS) and sodium dioctylsulfosuccinate (AOT) and starch nanoparticles hydrophobically modified with the hydrophobic dye pyrene (Py-SNPs) were investigated in ... -
Synergistic pH effect for reversible shuttling aptamer-based biosensors between graphene oxide and target molecules
(Royal Society of Chemistry, 2011-06-07)DNA aptamers are known to desorb from graphene oxide (GO) surface in the presence of target molecules. We demonstrate herein that the binding equilibrium can be shifted by simply tuning the solution pH. At lower pH, the ... -
Tandem DNAzymes for mRNA cleavage: choice of enzyme, metal ions and the antisense effect
(Elsevier, 2015-04-01)The concept of DNAzyme-based gene silencing via mRNA cleavage was proposed over twenty years ago. A number of studies regarding intracellular gene silencing have been reported as well. However, questions have been raised ...