Browsing Waterloo Institute for Nanotechnology by Author "Servos, Mark. R."
Now showing items 1-10 of 10
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Adsorption of DNA Oligonucleotides by Titanium Dioxide Nanoparticles
Zhang, Xu; Wang, Feng; Liu, Biwu; Kelly, Erin Y.; Servos, Mark R.; Liu, Juewen (American Chemical Society, 2014-01-28)Titanium dioxide (TiO2) or titania shows great promise in detoxification and drug delivery. To reach its full potential, it is important to interface TiO2 with biomolecules to harness their molecular recognition function. ... -
Effects of Polyethylene Glycol on DNA Adsorption and Hybridization on Gold Nanoparticles and Graphene Oxide
Zhang, Xu; Huang, Po-Jung Jimmy; Servos, Mark R.; Liu, Juewen (American Chemical Society, 2012-10-09)Understanding the interface between DNA and nanomaterials is crucial for rational design and optimization of biosensors and drug delivery systems. For detection and delivery into cells, where high concentrations of cellular ... -
Fast pH-assisted functionalization of silver nanoparticles with monothiolated DNA
Zhang, Xu; Servos, Mark R.; Liu, Juewen (Royal Society of Chemistry, 2012-10-18)Attaching monothiolated DNA to silver nanoparticles has been achieved at pH 3.0 in 30 minutes and difficulties associated with DNA attachment to AgNPs at neutral pH have been revealed by studying DNA adsorption kinetics. -
Gold nanoparticles as dehydrogenase mimicking nanozymes for estradiol degradation
Zhang, Zijie; Bragg, Leslie M.; Servos, Mark R.; Liu, Juewen (Elsevier, 2019-09)Nanozyme catalysis has been mainly focused on a few chromogenic and fluorogenic substrates, while environmentally and biologically important compounds need to be tested to advance the field. In this work, we studied oxidation ... -
Instantaneous and Quantitative Functionalization of Gold Nanoparticles with Thiolated DNA Using a pH-Assisted and Surfactant-Free Route
Zhang, Xu; Servos, Mark R.; Liu, Juewen (American Chemical Society, 2012-05-02)The attachment of thiolated DNA to gold nanoparticles (AuNPs) has enabled many landmark works in nanobiotechnology. This conjugate chemistry is typically performed using a salt-aging protocol where, in the presence of an ... -
Instantaneous Attachment of an Ultrahigh Density of Nonthiolated DNA to Gold Nanoparticles and Its Applications
Zhang, Xu; Dave, Neeshma; Servos, Mark R.; Liu, Juewen; Liu, Biwu (American Chemical Society, 2012-12-11)The last 16 years have witnessed the landmark development of polyvalent thiolated DNA-functionalized gold nanoparticles (AuNP's) possessing striking properties within the emerging field of nanobiotechnology. Many novel ... -
Polarity Control for Nonthiolated DNA Adsorption onto Gold Nanoparticles
Zhang, Xu; Liu, Biwu; Servos, Mark R.; Liu, Juewen (American Chemical Society, 2013-05-21)Gold nanoparticles (AuNPs) functionalized with thiolated DNA have enabled many studies in nanoscience. The strong thiol/gold affinity and the nanoscale curvature of AuNPs allow the attached DNA to adapt an upright conformation ... -
Surface Science of DNA Adsorption onto Citrate-Capped Gold Nanoparticles
Zhang, Xu; Servos, Mark R.; Liu, Juewen (American Chemical Society, 2012-02-28)Single-stranded DNA can be adsorbed by citrate capped gold nanoparticles (AuNPs), resulting in increased AuNP stability, which forms the basis of a number of biochemical and analytical applications, but the fundamental ... -
Toward Fast and Quantitative Modification of Large Gold Nanoparticles by Thiolated DNA: Scaling of Nanoscale Forces, Kinetics, and the Need for Thiol Reduction
Zhang, Xu; Gouriye, Tony; Göeken, Kristian; Servos, Mark R.; Gill, Ron; Liu, Juewen (American Chemical Society, 2013-08-01)We have recently reported on the fast and quantitative adsorption of DNA to 13 nm gold nanoparticles (AuNPs) at pH 3. This is in contrast to most traditional methods at neutral pH, where the adsorption is both slow and ... -
Ultrahigh Nanoparticle Stability against Salt, pH, and Solvent with Retained Surface Accessibility via Depletion Stabilization
Zhang, Xu; Servos, Mark R.; Liu, Juewen (American Chemical Society, 2012-06-20)For many applications, it is desirable to stabilize colloids over a wide range of buffer conditions while still retaining surface accessibility for adsorption and reaction. Commonly used charge or steric stabilization ...