Browsing Science (Faculty of) by Subject "Xenopus laevis"
Now showing items 1-8 of 8
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Analysis of heat shock protein 30 gene expression and function in Xenopus laevis A6 kidney epithelial cells
(University of Waterloo, 2014-04-30)Heat shock proteins (HSPs) are molecular chaperones that assist in protein synthesis, folding and degradation and prevent stress-induced protein aggregation. The present study examined the pattern of accumulation of HSP30 ... -
Antiviral responses of Xela DS2 and Xela VS2, two newly established Xenopus laevis skin epithelial-like cell lines, to viral dsRNA and Frog Virus 3
(University of Waterloo, 2019-09-27)There is a current decline in amphibian populations, wherein the emerging pathogen Frog Virus 3 (FV3) is believed to be a proximate cause. The conservation of frog species is thus important as population declines would ... -
Characterization of Cadmium-Induced BiP Accumulation in Xenopus laevis A6 Kidney Epithelial Cells
(University of Waterloo, 2016-08-19)In vertebrates, cadmium exposure is found to cause respiratory, neurological and kidney disorders. At the cellular level, cadmium can damage or modify proteins resulting in the production of toxic protein aggregates. The ... -
Characterization of HSP47 Expression in <i>Xenopus Laevis</i> Cell Culture and Embryos
(University of Waterloo, 2005)The heat shock or stress response is a transient response to stressful stimuli that protects vital cellular proteins from damage and irreversible aggregation. Heat shock proteins (Hsps) are molecular chaperones that ... -
Characterizing a role for α-parvin in Xenopus laevis Development
(University of Waterloo, 2021-09-20)In metazoans dynamic regulation of cell adhesion is critical for the cell movements that characterize gastrulation. It is clear that the adhesive property of cells is modulated in a highly coordinated spatial and temporal ... -
Effect of heat shock factor inhibitor, KNK437, on stress-induced hsp30 gene expression in Xenopus laevis A6 cells
(University of Waterloo, 2008-05-01)Prokaryotic and eukaryotic organisms respond to various stresses with the production of heat shock proteins (HSPs). HSPs are molecular chaperones that bind to unfolded proteins and inhibit their aggregation as well as ... -
Examination of Cadmium-Induced Heat Shock Protein Gene Expression in Xenopus laevis A6 Kidney Epithelial Cells
(University of Waterloo, 2008-05-21)Cadmium is a highly toxic chemical and has been classified by the International Agency for Research on Cancer as a human carcinogen. Cadmium is abundant in the environment, at specific work places, and in food and water. ... -
Stress-induced accumulation of heme oxygenase-1 in Xenopus laevis A6 kidney epithelial cells
(University of Waterloo, 2014-05-01)Abstract Previous studies have examined stress-induced heme oxygenase-1 (HO-1) expression primarily in mammalian systems. The present study examines, for the first time in amphibians, the effect of heat shock, sodium ...