Browsing Theses by Subject "microfluidics"
Now showing items 1-14 of 14
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Capillary-discharge ignition of dispersed-phase Al@CuO core-shell thermite particles in a liquid filled microchannel
(University of Waterloo, 2022-11-09)Aluminum based thermites are a broad class of highly tunable solid energetic materials that can be formulated to perform as pyrotechnics, propellants, or explosives. Their functional versatility, energy density, reactivity ... -
Design, Fabrication and Characterization of Electrokinetically Pumped Microfluidic Chips for Cell Culture Applications
(University of Waterloo, 2008-02-05)Continuous perfusion cell culture chips offer the biomedical researcher unprecedented control over the microenvironment surrounding the cell which is not feasible with conventional static cell culture procedures. Applying ... -
Development of a Microfluidic Hemodialysis Device Equipped with an Antifouling Nanoporous Dialysis Membrane
(University of Waterloo, 2021-06-08)This thesis presents a microfluidic hemodialyzer and an experimental platform and demonstrates that the performance of a polycarbonate membrane used in a continuous setting that can be comparable to commercial hollow-fibre ... -
Development of the integration of microwave technology with microfluidic systems for sensing and heating
(University of Waterloo, 2021-03-19)Microfluidics-based Lab-on-a-Chip platforms have drawn ever-increasing attention from both academy and industry due to their advantages for dealing with small volume of fluids and for integrating multiple processes into ... -
A Droplet Microfluidic Platform Used to Encapsulate Single Pre-formed Cancer Spheroids in Hydrogel Microenvironments
(University of Waterloo, 2024-04-19)Cancer has been a leading cause of death around the world for many years. Even with the emerging technologies seen in these times, there is still a lack of truly personalized treatments since cancer tumors are not fully ... -
Evaluation of Miniaturized Mixer and Integrated Optical Components for Cell Sorting
(University of Waterloo, 2008-09-24)Conventional cell cytometers are often bulky and thus not convenient for bio-medical analysis where portable devices are desired. They also suffer from the drawback of high cost due to the complicated and expensive optical ... -
Fabrication of microfluidic chip using 3D printing for ocular cell studies
(University of Waterloo, 2023-09-25)Purpose: This thesis aimed to create a polydimethylsiloxane (PDMS) microfluidic chip utilizing low-cost commercial 3D printers and to integrate human corneal epithelial cells (HCEC) into the fabricated chip. Methods: The ... -
Free-Flow Counterflow Gradient Focusing for Protein Fractionation
(University of Waterloo, 2022-09-23)In free-flow electrophoresis (FFE), a pressure-driven flow applied perpendicular to the electric field enables the continuous separation of charged solutes. Meanwhile, outlets located at the end of the separation region ... -
Induced-Charge Electrokinetic Motion of a Heterogeneous Particle and Its Corresponding Applications
(University of Waterloo, 2013-02-22)This thesis conducts numerical and experimental studies of the nonlinear electrokinetic motion of heterogeneous particles in microfluidic systems and their corresponding applications in laboratory-on-a-chip (LOC) systems. ... -
Miniaturization of Soft Robotic Control Systems and Actuators for Biomedical Applications
(University of Waterloo, 2023-09-26)Soft wearable robotics, a specialized branch of soft robotics, stands on the cusp of transforming the field of biomedical devices, particularly in the realm of assistive technology. This innovative approach offers a marked ... -
Preliminary Development of a Microfluidic Tool for the Characterization of Molecular Machines
(University of Waterloo, 2022-01-06)Transmembrane proteins cross the membranes of biological cells and perform integral cell functions that often must be described using quantum mechanics. Developing a better understanding of these quantum mechanical behaviours ... -
Rapid Prototyping Technologies for Processing of Nanomaterials with Applications to Microfluidics and Nanoelectronics
(University of Waterloo, 2017-08-09)The focus of this thesis is on the processing of nanomaterials using rapid prototyping technologies. To develop the necessary skills in fabrication and electronics, a thin film microheater was developed and applied to ... -
A Software Toolchain for Physical System Description and Synthesis, and Applications to Microfluidic Design Automation
(University of Waterloo, 2016-05-11)Microfluidic circuits are currently designed by hand, using a combination of the designer’s domain knowledge and educated intuition to determine unknown design parameters. As no microfluidic circuit design software exists ... -
Synthesis of Polymeric Nanoparticles for the Controlled Release of Hydrophobic and Hydrophillic Theraputic Compounds
(University of Waterloo, 2016-09-01)Polymeric nanoparticle (NP) drug carriers present a promising technology for controlled release since they are capable of improving the encapsulation efficiency and stability of the drugs inside the NPs and also able to ...