Browsing University of Waterloo by Subject "Hyperthermophiles"
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Investigation of enzymes catalyzing the production of acetaldehyde from pyruvate in hyperthermophiles
(University of Waterloo, 2012-09-26)Extreme thermophiles and hyperthermophiles are microorganisms capable of growing optimally at 65-79°C and 80°C plus, respectively. Many of the enzymes isolated from them are thermostable, which makes them a potential ... -
Investigation of Flavoproteins Involved in the Metabolism of Anaerobic Hyperthermophilic Microorganisms
(University of Waterloo, 2007-09-12)It was estimated that more than one hundred open reading frames in Pyrococcus furiosus and Thermotoga maritima could encode flavoproteins based on the results of motif search and comparison of genomic annotation to the ... -
Molecular Characterization of Zinc- and Iron- Containing Alcohol Dehydrogenases from Anaerobic Hyperthermophiles
(University of Waterloo, 2009-02-19)Hyperthermophiles grow optimally at 80 ºC and above, and many of them have the ability to utilize various carbohydrates as carbon source and produce ethanol as an end product. Alcohol dehydrogenase (ADH) is a key enzyme ... -
Purification and Characterization of O2-insensitive Pyruvate Decarboxylase from Sulfolobus species
(University of Waterloo, 2020-06-17)Pyruvate decarboxylase (PDC) is a key enzyme in a two-step pathway for the production of ethanol. It catalyzes the non-oxidative decarboxylation of pyruvate to acetaldehyde in many mesophilic organisms. No conventional PDC ... -
Solvent production by the hyperthermophilic archaeon Hyperthermus butylicus
(University of Waterloo, 2021-08-27)Hyperthermus butylicus is one of the few hyperthermophilic (organisms that thrive in temperatures 80°C and above) archaea that can produce 1-butanol as a major fermentation end-product. The reported end-products (acetone, ...