Browsing Waterloo Research by Title
Now showing items 635-654 of 2463
-
DNA-Functionalized Gold Nanoparticles in Macromolecularly Crowded Polymer Solutions
(American Chemical Society, 2012-11-15)DNA-functionalized gold nanoparticles (AuNPs) are one of the most commonly used reagents in nanobiotechnology. They are important not only for practical applications in analytical chemistry and drug delivery, but also for ... -
DNA-Functionalized Monolithic Hydrogels and Gold Nanoparticles for Colorimetric DNA Detection
(American Chemical Society, 2010-12-22)Highly sensitive and selective DNA detection plays a central role in many fields of research, and various assay platforms have been developed. Compared to homogeneous DNA detection, surface-immobilized probes allow washing ... -
DNA-Length-Dependent Fluorescence Signaling on Graphene Oxide Surface
(Wiley, 2012-02-10)Fluorescence energy transfer to graphene oxide is studied using covalently linked DNA probes ranging from 4 to 70 base pairs. The characteristic distance and mechanism of energy transfer are reported. -
DNAzyme Hybridization, Cleavage, Degradation and Sensing in Undiluted Human Blood Serum
(American Chemical Society, 2015-04-07)RNA-cleaving DNAzymes provide a unique platform for developing biosensors. However, a majority of the work has been performed in clean buffer solutions, while the activity of some important DNAzymes in biological sample ... -
A DNAzyme requiring two different metal ions at two distinct sites
(Oxford University Press, 2015-12-10)Most previously reported RNA-cleaving DNAzymes require only a single divalent metal ion for catalysis. We recently reported a general trivalent lanthanide-dependent DNAzyme named Ce13d. This work shows that Ce13d requires ... -
Do school physical activity policies and programs have a role in decreasing multiple screen time behaviours among youth?
(Elsevier, 2017-11-29)Screen time in youth has been associated with a wide range of poor health outcomes. Evidence indicates the need to develop physical activity (PA) school policies and programs that are aimed at decreasing youth screen time ... -
Dodging Monsters and Dancing with Dreams: Success and Failure at Different Levels of Approach and Avoidance
(SAGE Publications, 2013-07-01)Many models of motivation suggest that goals can be arranged in a hierarchy, ranging from higher-level goals that represent desired end-states to lower-level means that operate in the service of those goals. We present a ... -
Does AI Remember? Neural Networks and the Right to be Forgotten
(2020-04-14)The Right to be Forgotten is part of the recently enacted General Data Protection Regulation law that affects any data holder that has data on European Union residents. It gives EU residents the ability to request deletion ... -
Does Cox analysis of a randomized survival study yield a causal treatment effect?
(Springer US, 2015-10)Statistical methods for survival analysis play a central role in the assessment of treatment effects in randomized clinical trials in cardiovascular disease, cancer, and many other fields. The most common approach to ... -
Does History Matter? Pioneering Research on Canada's Attitudes Toward Bygone Days
(The LIterary Review of Canada, 2014-05)A book review of 'Canadians and their past' by Margaret Conrad, Kadriye Ercikan, Gerald Friesen, Jocelyn Létourneau, Delphin Muise, David Northrup and Peter Seixas. -
Does Stress-Related Poor Diet Quality Explain Socioeconomic Inequities in Health? A Structural Equation Mediation Analysis in Women and Men
(Oxford University Press, 2021-06)Objectives Individuals with a lower socioeconomic position (SEP) have poorer health than their more advantaged counterparts. Psychosocial stress and diet quality have been shown to individually mediate associations between ... -
Doing the work: Editing Wikipedia as an act of reconciliation
(On Archivy, 2018-08-28)The Truth and Reconciliation Commission of Canada Calls to Action outline the responsibilities of cultural heritage workers to educate both themselves and the general public about the Canadian Indian Residential School ... -
Dose-dependent dissociation of pro-cognitive effects of donepezil on attention and cognitive flexibility in rhesus monkeys
(Elsevier, 2021-11)BACKGROUND Donepezil exerts pro-cognitive effects by non-selectively enhancing acetylcholine (ACh) across multiple brain systems. Two brain systems that mediate pro-cognitive effects of attentional control and cognitive ... -
Double Bubbles Sans Toil and Trouble: Discrete Circulation-Preserving Vortex Sheets for Soap Films and Foams
(Association for Computing Machinery, 2015-08-01)Simulating the delightful dynamics of soap films, bubbles, and foams has traditionally required the use of a fully three-dimensional many-phase Navier-Stokes solver, even though their visual appearance is completely dominated ... -
Driving Adsorbed Gold Nanoparticle Assembly by Merging Lipid Gel/Fluid Interfaces
(American Chemical Society, 2015-11-23)Surface forces between inorganic nanoparticles and lipid bilayer is of great relevance to biophysics, medicine, and nanobiotechnology. Adsorbed nanoparticles may influence the fluidity of the underlying lipids, which may ... -
Driving under the influence behaviours among high school students who mix alcohol with energy drinks
(Elsevier, 2018-06-01)Alcohol and energy drinks are commonly used substances by youth in Canada, and are often mixed (AmED). While several studies have shown that AmED can have dangerous effects, less well understood is how AmED is associated ... -
Droplet formation in microfluidic T-junction generators operating in the transitional regime. I. Experimental observations
(American Physical Society Physics, 2012-01-26)This is the first part of a two-part study on the generation of droplets at a microfluidic T-junction operating in the transition regime where confinement of the droplet creates a large squeezing pressure that influences ... -
Droplet formation in microfluidic T-junction generators operating in the transitional regime. II. Modeling
(American Physical Society Physics, 2012-01-26)This is the second part of a two-part study on the generation of droplets at a microfluidic T-junction operating in the transition regime. In the preceding paper [Phys. Rev. E 85, 016322 (2012)], we presented our experimental ... -
Droplet formation in microfluidic T-junction generators operating in the transitional regime. III. Dynamic surfactant effects
(American Physical Society Physics, 2012-08-13)This study extends our previous work on droplet generation in microfluidic T-junction generators to include dynamic interfacial tension effects created by the presence of surfactants. In Paper I [T. Glawdel, C. Elbuken, ... -
Droplet Microfluidic System with On-Demand Trapping and Releasing of Droplet for Drug Screening Applications
(American Chemical Society (ACS), 2017-01-03)96-Well plate has been the traditional method used for screening drug compounds libraries for potential bioactivity. Although this method has been proven successful in testing doseÐresponse analysis, the microliter consumption ...