Browsing Optometry and Vision Science by Author "Phan, Chau-Minh"
Now showing items 1-5 of 5
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Antifungal ocular drug delivery via contact lenses using a novel in vitro eye model
Phan, Chau-Minh (University of Waterloo, 2016-04-21)Purpose: The purpose of this thesis was to evaluate the potential of contact lenses (CLs) as an antifungal drug delivery device, and to develop an in vitro eye model to test thereof. Methods: The first three chapters ... -
Development of an In Vitro Ocular Platform to Test Contact Lenses
Phan, Chau-Minh; Walther, Hendrik; Gao, Huayi; Rossy, Jordan; Subbaraman, Lakshman N.; Jones, Lyndon W. (Journal of Visualized Experiments, 2016-06-04)Currently, in vitro evaluations of contact lenses (CLs) for drug delivery are typically performed in large volume vials,1-6 which fail to mimic physiological tear volumes.7 The traditional model also lacks the natural tear ... -
Insights to Using Contact Lenses for Drug Delivery
Phan, Chau-Minh; Walther, Hendrik; Gao, Huayi; Rossy, Jordan; Subbaraman, Lakshman N.; Jones, Lyndon W. (Omics International, 2013)There has been considerable interest in the potential application of contact lenses for ocular drug delivery. This short communication provides an overview of the challenges faced by delivering drugs using contact lenses, ... -
Release of Ciprofloxacin and Moxifloxacin From Daily Disposable Contact Lenses From an In Vitro Eye Model
Bajgrowicz-Cieslak, Magdalena; Phan, Chau-Minh; Subbaraman, Lakshman N.; Jones, Lyndon W. (Association for Research in Vision and Ophthalmology, 2015-10-04)Purpose.: To analyze the release of two fluoroquinolones, ciprofloxacin and moxifloxacin, from conventional hydrogel (CH) and silicone hydrogel (SH) daily disposable contact lenses (CLs), comparing release from a fixed-volume ... -
Release of Moxifloxacin from Contact Lenses Using an In Vitro Eye Model: Impact of Artificial Tear Fluid Composition and Mechanical Rubbing
Phan, Chau-Minh; Bajgrowicz-Cieslak, Magdalena; Subbaraman, Lakshman N.; Jones, Lyndon W. (Association for Research in Vision and Ophthalmology, 2016-08-11)Purpose: The aim of this study was to evaluate and compare the release of moxifloxacin from a variety of daily disposable (DD) contact lenses (CLs) under various conditions using a novel in vitro eye model. Methods: Four ...