Browsing Theses by Subject "metabolic flux analysis"
Now showing items 1-2 of 2
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Modelling Batch and Fed-batch Mammalian Cell Cultures for Optimizing MAb Productivity
(University of Waterloo, 2007-08-21)The large-scale production of monoclonal antibodies (MAb) by mammalian cells in batch and fed-batch culture systems is limited by the unwanted decline in cell viability and reduced productivity that may result from changes ... -
Optimization of Recombinant Protein Production by a Fungal Host
(University of Waterloo, 2007-04-05)The natural ability of filamentous fungi to synthesize, glycosylate, and secrete high levels of protein products has made them potentially attractive hosts for heterologous protein production. Advances in fungal genetics ...