Browsing Theses by Subject "Atomic force microscopy"
Now showing items 1-5 of 5
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Atomic Force Microscopy Study of Model Lipid Monolayers
(University of Waterloo, 2012-09-26)Alzheimer's Disease (AD) is a neurodegenerative disorder that is prevalent among the elderly population. Aß protein has been heavily implicated in the pathogenesis of AD. This protein in its fibrillar form is a major ... -
Developing Applications of Atomic Force Microscopy in Cellular Imaging and Mechanical Property Measurement
(University of Waterloo, 2014-09-10)Health of human body is strongly associated with the mechanical properties of living cells. Here, atomic force microscope (AFM) was applied to obtain surface microscopy of individual and non-individual biological cells, ... -
Microfluidic-Based In-Situ Functionalization for Detection of Proteins in Heterogeneous Immunoassays
(University of Waterloo, 2013-01-17)One the most daunting technical challenges in the realization of biosensors is functionalizing transducing surfaces for the detection of biomolecules. Functionalization is defined as the formation of a bio-compatible ... -
Nanofabrication and its Application in Atomic Force Microscopy (AFM)
(University of Waterloo, 2015-09-16)This thesis is focused on nanofabrication and its application in atomic force microscopy (AFM). The contribution of this thesis is thus the development, investigation and characterization of novel nanofabrication technique ... -
The Role of Melatonin in Amyloid Interactions with the Model Neuronal Membranes
(University of Waterloo, 2023-11-29)The amyloid cascade hypothesis has long directed research efforts in understanding the pathogenesis of Alzheimer’s disease (AD), ever since it was first proposed through clinical evidence by Hardy and Higgins in 1992. ...