dc.contributor.author | Woods, Jill | |
dc.contributor.author | Guthrie, Sarah E. | |
dc.contributor.author | Keir, Nancy | |
dc.contributor.author | Dillehay, Sally | |
dc.contributor.author | Tyson, Mark | |
dc.contributor.author | Griffin, Richard | |
dc.contributor.author | Choh, Vivian Cheng-Pei | |
dc.contributor.author | Fonn, Desmond | |
dc.contributor.author | Jones, Lyndon W. | |
dc.contributor.author | Irving, Elizabeth | |
dc.date.accessioned | 2017-03-07 19:47:56 (GMT) | |
dc.date.available | 2017-03-07 19:47:56 (GMT) | |
dc.date.issued | 2013-04-12 | |
dc.identifier.uri | http://dx.doi.org/10.1167/iovs.12-10742 | |
dc.identifier.uri | http://hdl.handle.net/10012/11456 | |
dc.description | Woods, J., Guthrie, S. E., Keir, N., Dillehay, S., Tyson, M., Griffin, R., … Irving, E. (2013). Inhibition of Defocus-Induced Myopia in Chickens. Investigative Opthalmology & Visual Science, 54(4), 2662. https://doi.org/10.1167/iovs.12-10742 | en |
dc.description.abstract | Purpose.: To determine the effect of wearing a lens with a unique peripheral optical design on the development and progression of defocus-induced myopia in newly hatched chickens.Methods.: Eighty-five newly hatched chickens underwent bilateral retinoscopy and A-scan ultrasound to determine their refractive error and axial length. They were randomly divided into Control and two Test groups, in which each chicken was fitted with a goggle-lens over the right eye, with the left eye remaining untreated. The Control group wore a lens of power −10.00 diopters (D) of standard spherical optical design. The two Test lenses both had a central optical power −10.00 D, but used different peripheral myopia progression control (MPC) designs. For all groups, retinoscopy was repeated on days 3, 7, 10, and 14; ultrasound was repeated on day 14.
Results.: On day 0 there was no statistical difference in refractive error (mean +6.92 D) or axial length (mean 8.06 mm) between Test and Control groups or treated and untreated eyes (all P > 0.05). At day 14, 37 (43.5%) of 85 chickens had not experienced goggle detachment and were included in the final analyses. In this cohort there was a significant refractive difference between the treated eyes of the Control group (n = 17) and those of Test 1 (n = 14) and Test 2 (n = 6) groups (both P < 0.01): Control −4.65 ± 2.11 D, Test 1 +4.57 ± 3.11 D, Test 2 +1.08 ± 1.24 D (mean ± SEM). There was also a significant axial length difference (both P < 0.01): Control 10.55 ± 0.36 mm, Test 1 9.99 ± 0.14 mm, Test 2 10.17 ± 0.18 mm.
Conclusions.: Use of these unique MPC lens designs over 14 days caused a significant reduction in the development of defocus-induced myopia in chickens; the degree of reduction appeared to be design specific. | en |
dc.language.iso | en | en |
dc.publisher | Association for Research in Vision and Ophthalmology | en |
dc.rights | Attribution 4.0 International | * |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Myopia control | en |
dc.subject | Emmetropization | en |
dc.subject | Refractive error | en |
dc.subject | Eye growth | en |
dc.subject | Multifocal lens | en |
dc.title | Inhibition of Defocus-Induced Myopia in Chickens | en |
dc.type | Article | en |
dcterms.bibliographicCitation | Woods, J., Guthrie, S. E., Keir, N., Dillehay, S., Tyson, M., Griffin, R., … Irving, E. (2013). Inhibition of Defocus-Induced Myopia in Chickens. Investigative Opthalmology & Visual Science, 54(4), 2662. https://doi.org/10.1167/iovs.12-10742 | en |
uws.contributor.affiliation1 | Faculty of Science | en |
uws.contributor.affiliation2 | School of Optometry and Vision Science | en |
uws.typeOfResource | Text | en |
uws.peerReviewStatus | Reviewed | en |
uws.scholarLevel | Faculty | en |