| dc.contributor.author | Wang, Feng | |
| dc.contributor.author | Huang, Po-Jung Jimmy | |
| dc.contributor.author | Liu, Juewen | |
| dc.date.accessioned | 2017-03-01 17:38:25 (GMT) | |
| dc.date.available | 2017-03-01 17:38:25 (GMT) | |
| dc.date.issued | 2013-10-21 | |
| dc.identifier.uri | http://dx.doi.org/10.1039/C3CC45458D | |
| dc.identifier.uri | http://hdl.handle.net/10012/11397 | |
| dc.description.abstract | The reaction between cisplatin and DNA is conveniently studied using fluorescently labeled oligonucleotides and gel electrophoresis; as an example of application, the inhibition of this reaction by citrate is demonstrated, which might increase selectivity of cisplatin towards guanine over adenine. | en |
| dc.description.sponsorship | University of Waterloo ||
Canadian Foundation for Innovation ||
Natural Sciences and Engineering Research Council ||
Ontario Ministry of Research, Innovation and Science || | en |
| dc.language.iso | en | en |
| dc.publisher | Royal Society of Chemistry | en |
| dc.subject | DNA | en |
| dc.subject | citrate | en |
| dc.subject | fluorescence | en |
| dc.title | Citrate inhibition of cisplatin reaction with DNA studied using fluorescently labeled oligonucleotides: implication for selectivity towards guanine | en |
| dc.type | Article | en |
| dcterms.bibliographicCitation | Wang, F., Huang, P.-J. J., & Liu, J. (2013). Citrate inhibition of cisplatin reaction with DNA studied using fluorescently labeled oligonucleotides: implication for selectivity towards guanine. Chemical Communications, 49(82), 9482. https://doi.org/10.1039/c3cc45458d | en |
| uws.contributor.affiliation1 | Faculty of Science | en |
| uws.contributor.affiliation2 | Chemistry | en |
| uws.contributor.affiliation2 | Waterloo Institute for Nanotechnology (WIN) | en |
| uws.typeOfResource | Text | en |
| uws.peerReviewStatus | Reviewed | en |
| uws.scholarLevel | Faculty | en |
