Citrate inhibition of cisplatin reaction with DNA studied using fluorescently labeled oligonucleotides: implication for selectivity towards guanine

Simple item page
dc.contributor.authorWang, Feng
dc.contributor.authorHuang, Po-Jung Jimmy
dc.contributor.authorLiu, Juewen
dc.date.accessioned2017-03-01T17:38:25Z
dc.date.available2017-03-01T17:38:25Z
dc.date.issued2013-10-21
dc.description.abstractThe reaction between cisplatin and DNA is conveniently studied using fluorescently labeled oligonucleotides and gel electrophoresis; as an example of application, the inhibition of this reaction by citrate is demonstrated, which might increase selectivity of cisplatin towards guanine over adenine.en
dc.description.sponsorshipUniversity of Waterloo || Canadian Foundation for Innovation || Natural Sciences and Engineering Research Council || Ontario Ministry of Research, Innovation and Science ||en
dc.identifier.urihttp://dx.doi.org/10.1039/C3CC45458D
dc.identifier.urihttp://hdl.handle.net/10012/11397
dc.language.isoenen
dc.publisherRoyal Society of Chemistryen
dc.subjectDNAen
dc.subjectcitrateen
dc.subjectfluorescenceen
dc.titleCitrate inhibition of cisplatin reaction with DNA studied using fluorescently labeled oligonucleotides: implication for selectivity towards guanineen
dc.typeArticleen
dcterms.bibliographicCitationWang, F., Huang, P.-J. J., & Liu, J. (2013). Citrate inhibition of cisplatin reaction with DNA studied using fluorescently labeled oligonucleotides: implication for selectivity towards guanine. Chemical Communications, 49(82), 9482. https://doi.org/10.1039/c3cc45458den
uws.contributor.affiliation1Faculty of Scienceen
uws.contributor.affiliation2Chemistryen
uws.contributor.affiliation2Waterloo Institute for Nanotechnology (WIN)en
uws.peerReviewStatusRevieweden
uws.scholarLevelFacultyen
uws.typeOfResourceTexten

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Liu_Juewen(20).pdf
Size:
573.09 KB
Format:
Adobe Portable Document Format
Description:
Post-print
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
4.46 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Waterloo Research
Chemistry
Waterloo Institute for Nanotechnology