Two Pb2+-specific DNAzymes with opposite trends in split-site-dependent activity

dc.contributor.author	Huang, Po-Jung Jimmy
dc.contributor.author	Liu, Juewen
dc.date.accessioned	2017-02-24 20:03:24 (GMT)
dc.date.available	2017-02-24 20:03:24 (GMT)
dc.date.issued	2014-05-04
dc.identifier.uri	http://dx.doi.org/10.1039/C4CC00864B
dc.identifier.uri	http://hdl.handle.net/10012/11358
dc.description.abstract	By splitting the catalytic core of DNAzymes into two halves, two Pb2+-specific DNAzymes retain partial activity, while they show opposite trends of activity as a function of the split site, revealing important nucleotides for catalysis and metal binding.	en
dc.description.sponsorship	University of Waterloo \|\| Canadian Foundation for Innovation \|\| Natural Sciences and Engineering Research Council \|\| Ministry of Research and Innovation of Ontario \|\|	en
dc.language.iso	en	en
dc.publisher	Royal Society of Chemistry	en
dc.subject	DNAzymes	en
dc.subject	catalysis	en
dc.subject	metal binding	en
dc.subject	Lead	en
dc.title	Two Pb2+-specific DNAzymes with opposite trends in split-site-dependent activity	en
dc.type	Article	en
dcterms.bibliographicCitation	Huang, P.-J. J., & Liu, J. (2014). Two Pb2+-specific DNAzymes with opposite trends in split-site-dependent activity. Chemical Communications, 50(34), 4442. https://doi.org/10.1039/c4cc00864b	en
uws.contributor.affiliation1	Faculty of Science	en
uws.contributor.affiliation2	Chemistry	en
uws.contributor.affiliation2	Waterloo Institute for Nanotechnology (WIN)	en
uws.typeOfResource	Text	en
uws.peerReviewStatus	Reviewed	en
uws.scholarLevel	Faculty	en