Two Pb2+-specific DNAzymes with opposite trends in split-site-dependent activity
| dc.contributor.author | Huang, Po-Jung Jimmy | |
| dc.contributor.author | Liu, Juewen | |
| dc.date.accessioned | 2017-02-24T20:03:24Z | |
| dc.date.available | 2017-02-24T20:03:24Z | |
| dc.date.issued | 2014-05-04 | |
| dc.description.abstract | By splitting the catalytic core of DNAzymes into two halves, two Pb2+-specific DNAzymes retain partial activity, while they show opposite trends of activity as a function of the split site, revealing important nucleotides for catalysis and metal binding. | en |
| dc.description.sponsorship | University of Waterloo || Canadian Foundation for Innovation || Natural Sciences and Engineering Research Council || Ministry of Research and Innovation of Ontario || | en |
| dc.identifier.uri | http://dx.doi.org/10.1039/C4CC00864B | |
| dc.identifier.uri | http://hdl.handle.net/10012/11358 | |
| dc.language.iso | en | en |
| dc.publisher | Royal Society of Chemistry | en |
| dc.subject | DNAzymes | en |
| dc.subject | catalysis | en |
| dc.subject | metal binding | en |
| dc.subject | Lead | en |
| dc.title | Two Pb2+-specific DNAzymes with opposite trends in split-site-dependent activity | en |
| dc.type | Article | en |
| dcterms.bibliographicCitation | Huang, P.-J. J., & Liu, J. (2014). Two Pb2+-specific DNAzymes with opposite trends in split-site-dependent activity. Chemical Communications, 50(34), 4442. https://doi.org/10.1039/c4cc00864b | en |
| uws.contributor.affiliation1 | Faculty of Science | en |
| uws.contributor.affiliation2 | Chemistry | en |
| uws.contributor.affiliation2 | Waterloo Institute for Nanotechnology (WIN) | en |
| uws.peerReviewStatus | Reviewed | en |
| uws.scholarLevel | Faculty | en |
| uws.typeOfResource | Text | en |