Estimation and Assessment of Markov Multistate Models with Intermittent Observations on Individuals

dc.contributor.authorLawless, Jerald F.
dc.date.accessioned2016-10-24T16:00:19Z
dc.date.available2016-10-24T16:00:19Z
dc.date.issued2015-04
dc.descriptionThe final publication: Lawless, J.F. and Nazeri Rad, N. (2015). Estimation and assessment of markov multistate models with intermittent observations on individuals. Lifetime Data Analysis, 21 (2), 160--179 is available at Springer via http://link.springer.com/article/10.1007/s10985-014-9310-z. DOI: 10.1007/s10985-014-9310-zen
dc.description.abstractMultistate models provide important methods of analysis for many life history processes, and this is an area where John Klein made numerous contributions. When individuals in a study group are observed continuously so that all transitions between states, and their times, are known, estimation and model checking is fairly straightforward. However, individuals in many studies are observed intermittently, and only the states occupied at the observation times are known. We review methods of estimation and assessment for Markov models in this situation. Numerical studies that show the effects of inter-observation times are provided, and new methods for assessing fit are given. An illustration involving viral load dynamics for HIV-positive persons is presented.en
dc.description.sponsorshipNatural Sciences and Engineering Research Council of Canada || (JFL RGPIN 8597)en
dc.identifier.urihttp://dx.doi.org/10.1007/s10985-014-9310-z
dc.identifier.urihttp://hdl.handle.net/10012/11013
dc.language.isoenen
dc.publisherSpringeren
dc.relation.ispartofseriesLifetime Data Analysis;21 (2)en
dc.subjectGoodness of fiten
dc.subjectMaximum likelihooden
dc.subjectPanel dataen
dc.subjectPrevalence probabilityen
dc.subjectRelative efficiencyen
dc.subjectTransition intensityen
dc.subjectTransition probabilityen
dc.titleEstimation and Assessment of Markov Multistate Models with Intermittent Observations on Individualsen
dc.title.alternativeMultistate Models with Intermittent Observationen
dc.typeArticleen
dcterms.bibliographicCitationLawless, J. F., and N. Nazeri Rad. "Estimation and assessment of markov multistate models with intermittent observations on individuals." Lifetime data analysis 21.2 (2015): 160-179.en
uws.contributor.affiliation1Faculty of Mathematicsen
uws.contributor.affiliation2Statistics and Actuarial Scienceen
uws.peerReviewStatusRevieweden
uws.scholarLevelFacultyen
uws.typeOfResourceTexten

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